4 results match your criteria: "The National Institute of Occupational Health in Norway[Affiliation]"
Transcriptional and phenotypical alterations associated with a gradual benzo[a]pyrene-induced transition of human bronchial epithelial cells into mesenchymal-like cells.
Environ Toxicol Pharmacol
April 2024
Department of Pharmacology and Toxicology, Veterinary Research Institute, Hudcova 70, Brno 62100, Czech Republic. Electronic address:
The role of benzo[a]pyrene (BaP), a prominent genotoxic carcinogen and aryl hydrocarbon receptor (AhR) ligand, in tumor progression remains poorly characterized. We investigated the impact of BaP on the process of epithelial-mesenchymal transition (EMT) in normal human bronchial epithelial HBEC-12KT cells. Early morphological changes after 2-week exposure were accompanied with induction of SERPINB2, IL1, CDKN1A/p21 (linked with cell cycle delay) and chemokine CXCL5.
View Article and Find Full Text PDFOccupational noise exposure and tinnitus: the HUNT Study.
Int J Audiol
November 2024
Department of Physical Health and Ageing, The Norwegian Institute of Public Health, Oslo, Norway.
Objective: We aimed to assess the association between occupational noise exposure and tinnitus. Further, to assess whether the association depends on hearing status.
Design: In this cross-sectional study, tinnitus (>1 h daily) was regressed on job exposure matrix (JEM)-based or self-reported occupational noise exposure, adjusted for confounders.
Quantitative levels of noise exposure and 20-year hearing decline: findings from a prospective cohort study (the HUNT Study).
Int J Audiol
January 2024
Department of Occupational Medicine and Epidemiology, The National Institute of Occupational Health in Norway, Oslo, Norway.
Objective: We aimed to assess the association between occupational noise exposure and long-term hearing decline.
Design: This prospective cohort study used linear regression to investigate the association between occupational noise exposure and 20-year hearing decline, adjusted for important confounders.
Study Sample: The Norwegian cohort ( = 4,448) participated in two population-based health studies with pure-tone audiometry; HUNT2 1996-1998 and HUNT4 2017-2019.
Occupation and 20-year hearing decline: findings from The HUNT Study.
Occup Med (Lond)
December 2022
The National Institute of Occupational Health in Norway, Oslo, Norway.
Background: Studies show that certain occupations are associated with an increased risk of hearing loss. However, many studies are cross-sectional, and the few longitudinal studies are mostly small or focus on only one occupation.
Aims: We aimed to quantify the long-term hearing decline among workers in different occupations and assess whether the change differs between the occupations.