Study on the executive function of attention in depression patients based on SPECT technology.

Objective: To investigate event-related potential in executive function of attention and characteristics of cerebral perfusion by 99mTc-ECD single-photon emission computed tomography (SPECT) in depression patients receiving the Oddball task.

Methods: A total of 30 depression patients and 30 normal control subjects were selected to carry out the Oddball task. Event-related potential (ERP) technology combined with SPECT imaging technology was used to compare the reaction time, ERP-P300 latency and amplitude, and cerebral perfusion characteristics on sites of brain.