7,983 results match your criteria: "The Lancet. Infectious diseases[Journal]"
Review of the WHO guideline on preventive chemotherapy for public health control of strongyloidiasis.
Lancet Infect Dis
October 2024
Department of Control of Neglected Tropical Diseases, WHO, Geneva, Switzerland.
Article Synopsis
- Strongyloidiasis is a widespread parasitic infection affecting 300-600 million people, particularly in tropical regions, and poses serious health risks, especially during immunosuppression, with high fatality rates.
- There have been no significant global health initiatives targeting this disease until recently, when the WHO included it in their roadmap for controlling neglected tropical diseases, highlighting its importance.
- The new WHO guidelines recommend mass drug administration of ivermectin in areas with a prevalence of over 5%, aiming for effective public health strategies to combat strongyloidiasis.
The effect of Plasmodium falciparum exposure and maternal anti-circumsporozoite protein antibodies on responses to RTS,S/AS01 vaccination in infants and children: an ancillary observational immunological study to a phase 3, randomised clinical trial.
Lancet Infect Dis
October 2024
ISGlobal, Barcelona, Catalonia, Spain; Facultat de Medicina i Ciències de la Salut, Universitat de Barcelona, Barcelona, Spain; CIBER de Enfermedades Infecciosas (CIBERINFEC), Barcelona, Spain. Electronic address:
Background: The RTS,S/AS01 malaria vaccine showed lower antibody response and protective efficacy in infants aged 6-12 weeks compared with children aged 5-17 months (for whom this vaccine is recommended). We aimed to study the effect of previous Plasmodium falciparum exposure on the antibody responses to RTS,S/AS01 vaccination in infants and children, and the mediating effect of baseline (including maternal) anti-circumsporozoite protein (CSP) antibodies.
Methods: In this observational study, we included children and infants from six African countries (Burkina Faso, Gabon, Ghana, Kenya, Mozambique, and Tanzania) enrolled in the MAL067 immunology ancillary study of the RTS,S/AS01 phase 3 clinical trial from March 27, 2009, to Jan 21, 2011.
Understanding the immunogenicity of RTS,S in infants.
Lancet Infect Dis
October 2024
Department of Malaria Vaccine Development, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka 565-0871, Japan. Electronic address:
Steps towards licensure of self-amplifying RNA vaccines.
Lancet Infect Dis
October 2024
Department of Viroscience, Erasmus University Medical Center, Rotterdam 3015 GD, Netherlands. Electronic address:
Immunogenicity of a booster dose of a bivalent (Asp614Gly and omicron BA.4/5 variant) self-amplifying mRNA SARS-CoV-2 booster vaccine versus the BNT162b2 omicron BA.4/5 mRNA vaccine: a randomised phase 3 trial.
Lancet Infect Dis
October 2024
Walson Consulting, Seattle, WA, USA. Electronic address:
Background: We previously showed that ARCT-154, a self-amplifying mRNA COVID-19 vaccine, had improved immunogenicity and antibody persistence compared with conventional mRNA or adenovirus vector vaccines. In this study, we compared ARCT-2301, a bivalent self-amplifying mRNA vaccine (Asp614Gly and omicron BA.4/5 variant), with the bivalent Comirnaty omicron BA.
View Article and Find Full Text PDFRare presentation of rapidly progressive tertiary syphilis in AIDS: a case report of syphilitic gumma.
Lancet Infect Dis
November 2024
Department of Dermatology, Northwest Hospital, The Second Hospital Affiliated to Xi'an Jiaotong University, Xi'an, China. Electronic address:
Circulation of avian Chlamydia abortus in the Netherlands and community-acquired pneumonia: an outbreak investigation and retrospective cohort study.
Lancet Infect Dis
October 2024
Department of Medical Microbiology (and reference laboratory for human chlamydia infections from animal origin), Zuyderland Medical Center, Sittard-Geleen, Netherlands.
Background: In 2021, a novel group of Chlamydia strains in wild birds was classified as avian Chlamydia abortus, with unknown zoonotic potential. We report relevant features of avian C abortus infections from a Dutch family cluster and unrelated historical cases using clinical, epidemiological, and microbiological data.
Methods: An outbreak of avian C abortus started in the Netherlands in December, 2022.
Zoonotic chlamydial infections: what's new?
Lancet Infect Dis
October 2024
National and international Reference Laboratory for Ovine Chlamydiosis, Institute of Veterinary Pathology, University of Zurich, CH-8057 Zurich, Switzerland. Electronic address:
Oropouche virus and potential birth defects.
Lancet Infect Dis
October 2024
Laboratory of Clinical Research on Acute Febrile Illnesses, Evandro Chagas National Institute of Infectious Diseases, Oswaldo Cruz Foundation (Fiocruz), Rio de Janeiro, RJ, Brazil.