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Article Synopsis
  • Neutropenia (NP), defined as an absolute blood neutrophil count (ANC) below 1.5 g/L, is associated with various diseases and was found in 4.9% of children and 1.9% of adults in a large study following over 370,000 individuals.
  • The study tracked neutropenic patients for 4 years to investigate the development of viral infections and hematological malignancies, revealing a strong correlation between lower ANC levels and the likelihood of such diagnoses.
  • In children, unspecified viral infections were most common, while adults primarily faced hepatitis, HIV, and hematological malignancies like acute myelogenous leukemia, emphasizing the need for vigilant monitoring of NP patients for potential underlying health issues.
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Background: Neutropenia, defined as an absolute blood neutrophil count (ANC) <1.5 G L(-1) , may accompany a variety of diseases. However, the clinical significance of neutropenia detected in a routine complete blood cell count is poorly understood.

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