41 results match your criteria: "The Joseph M. Sanzari Children's Hospital at Hackensack University Medical Center[Affiliation]"
Multisystem Inflammatory Syndrome in Children: Survey of Protocols for Early Hospital Evaluation and Management.
J Pediatr
February 2021
Division of Pediatric Cardiology, Department of Pediatrics, Children's Healthcare of Atlanta, Emory University, Atlanta, GA. Electronic address:
Objective: To describe the similarities and differences in the evaluation and treatment of multisystem inflammatory syndrome in children (MIS-C) at hospitals in the US.
Study Design: We conducted a cross-sectional survey from June 16 to July 16, 2020, of US children's hospitals regarding protocols for management of patients with MIS-C. Elements included characteristics of the hospital, clinical definition of MIS-C, evaluation, treatment, and follow-up.
Suspected neonatal sepsis is one of the most common diagnoses made in newborns (NBs), but very few NBs actually have sepsis. There is no international consensus to clearly define suspected neonatal sepsis, but each time that this suspected diagnosis is assumed, blood samples are taken, venous accesses are used to administer antibiotics, and the mother-child pair is separated, with prolonged hospital stays. X-rays, urine samples, and a lumbar puncture are sometimes taken.
View Article and Find Full Text PDFAmerican College of Rheumatology Clinical Guidance for Multisystem Inflammatory Syndrome in Children Associated With SARS-CoV-2 and Hyperinflammation in Pediatric COVID-19: Version 1.
Arthritis Rheumatol
November 2020
Children's Hospital of Philadelphia and University of Pennsylvania Perelman School of Medicine.
Objective: To provide guidance on the management of multisystem inflammatory syndrome in children (MIS-C), a condition characterized by fever, inflammation, and multiorgan dysfunction that manifests late in the course of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, and to provide recommendations for children with hyperinflammation during coronavirus disease 2019 (COVID-19), the acute, infectious phase of SARS-CoV-2 infection.
Methods: A multidisciplinary task force was convened by the American College of Rheumatology (ACR) to provide guidance on the management of MIS-C associated with SARS-CoV-2 and hyperinflammation in COVID-19. The task force was composed of 9 pediatric rheumatologists, 2 adult rheumatologists, 2 pediatric cardiologists, 2 pediatric infectious disease specialists, and 1 pediatric critical care physician.
Synthetic Surfactant CHF5633 Compared with Poractant Alfa in the Treatment of Neonatal Respiratory Distress Syndrome: A Multicenter, Double-Blind, Randomized, Controlled Clinical Trial.
J Pediatr
October 2020
Division of Neonatology, Department of Pediatrics, Floating Hospital for Children at Tufts Medical Center, Boston, MA.
Objective: To compare efficacy and safety of a new synthetic surfactant, CHF5633, enriched with surfactant proteins, SP-B and SP-C peptide analogues, with porcine surfactant, poractant alfa, for the treatment of respiratory distress syndrome in infants born preterm.
Study Design: Neonates born preterm on respiratory support requiring fraction of inspired oxygen (FiO) ≥0.30 from 24 to 26 weeks and FiO ≥0.
The 2020 Census and the child undercount: a threat to pediatric research and the health and wellbeing of children.
Pediatr Res
September 2019
Department of Pediatrics, University of Colorado School of Medicine, Aurora, CO, USA.
Epidemiology of Lower Extremity Deep Venous Thrombosis in Critically Ill Adolescents.
J Pediatr
October 2018
Department of Diagnostic Radiology, Yale School of Medicine, New Haven, CT.
Article Synopsis
- This study investigated how common lower extremity deep venous thrombosis (DVT) is in critically ill adolescents aged 13-17, as the existing data on this topic is limited.
- The research involved 88 adolescents in pediatric intensive care units, with serial ultrasounds revealing a DVT occurrence rate of 12.4%, particularly among those on mechanical ventilation.
- The findings suggest that factors like femoral central venous catheter placement and the severity of illness contribute to DVT risk, highlighting the need for further research on prevention strategies in this population.
Reproductive Coercion in High School-Aged Girls: Associations with Reproductive Health Risk and Intimate Partner Violence.
J Pediatr Adolesc Gynecol
December 2017
Division of Adolescent Medicine, Department of Pediatrics, Children's Hospital at Montefiore, Albert Einstein College of Medicine, Bronx, New York.
Study Objective: To determine the prevalence of reproductive coercion, a form of intimate partner violence (IPV) including contraceptive sabotage and pregnancy pressure, among urban high school-aged girls and to examine its associations with reproductive health risks.
Design And Setting: A self-administered survey completed by high school-aged girls living in high-poverty neighborhoods while awaiting medical care in a pediatric emergency room, inpatient service, school-based, and hospital-based clinic.
Participants: One hundred forty-nine sexually active girls aged 14-17 years.
Pediatric Acute Respiratory Distress Syndrome in Pediatric Allogeneic Hematopoietic Stem Cell Transplants: A Multicenter Study.
Pediatr Crit Care Med
April 2017
1Division of Critical Care, Department of Pediatrics, Riley Hospital for Children, Indiana University School of Medicine, Indianapolis IN. 2Division of Pediatric Critical Care Medicine, Department of Pediatrics, Seattle Children's Hospital, University of Washington, Seattle, WA. 3Division of Critical Care, Department of Pediatrics, Masonic Children's Hospital, University of Minnesota, Minneapolis, MN. 4Division of Critical Care, Department of Pediatrics, St. Jude's Children's Research Hospital, Memphis, TN. 5Division of Critical Care, Department of Pediatrics, Joseph M Sanzari Children's Hospital at Hackensack University Medical Center, Bergen County, NJ. 6Division of Critical Care, Department of Anesthesia, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA. 7Department of Biostatistics, Indiana University, Indianapolis IN. 8Division of Critical Care, Department of Pediatrics, Weil Cornell Medical College, New York Presbyterian Hospital, New York City, NY. 9Division of Oncology, Department of Pediatrics, Dana-Farber Cancer Institute Harvard University, Boston, MA. 10Division of Oncology, Department of Pediatrics, Children's Hospital at Montefiore, Albert Einstein College of Medicine, Bronx, NY. 11Division of Blood and Marrow Transplant, Department of Pediatrics, Duke Children's Hospital, Duke University, Durham, NC. 12Division of Critical Care, Department of Pediatrics, Nationwide Children's Hospital, The Ohio State University, Columbus, OH. 13Division of Critical Care, Department of Pediatrics, Penn State Hershey Children's Hospital, Pennsylvania State University College of Medicine, Hershey, PA. 14Division of Critical Care, Department of Pediatrics, Duke Children's Hospital, Duke University, Durham, NC.
Objective: Immunodeficiency is both a preexisting condition and a risk factor for mortality in pediatric acute respiratory distress syndrome. We describe a series of pediatric allogeneic hematopoietic stem cell transplant patients with pediatric acute respiratory distress syndrome based on the recent Pediatric Acute Lung Injury Consensus Conference guidelines with the objective to better define survival of this population.
Design: Secondary analysis of a retrospective database.
Invasive Mechanical Ventilation and Mortality in Pediatric Hematopoietic Stem Cell Transplantation: A Multicenter Study.
Pediatr Crit Care Med
April 2016
1Department of Pediatrics, Indiana University School of Medicine, Riley Hospital for Children, Indianapolis, IN. 2Department of Pediatrics, Joseph M. Sanzari Children's Hospital at Hackensack University Medical Center, Hackensack, NJ. 3Department of Pediatrics, Medical College of Wisconsin, Children's Hospital of Wisconsin, Milwaukee, WI. 4Department of Anesthesia, Children's Hospital of Philadelphia University of Pennsylvania Perelman School of Medicine, Philadelphia, PA. 5Department of Pediatrics, University of Minnesota Masonic Children's Hospital, Minneapolis, MN. 6Department of Pediatrics, Weill Cornell Medical College, New York Presbyterian Hospital, New York, NY. 7Department of Pediatrics, Dana-Farber Cancer Institute, Boston, MA. 8Department of Pediatrics, Albert Einstein College of Medicine, Children's Hospital at Montefiore, Bronx, NY. 9Department of Pediatrics, University of Washington and Seattle Children's Hospital, Seattle, WA. 10Department of Pediatrics, Duke Children's Hospital, Durham, NC. 11Department of Pediatrics, Nationwide Children's Hospital, Columbus, OH. 12Department of Pediatrics, Pennsylvania State University College of Medicine, Penn State Hershey Children's Hospital, Hershey, PA. 13Department of Public Health, Pennsylvania State University College of Medicine, Penn State Hershey Children's Hospital, Hershey, PA.
Objective: To establish the current respiratory practice patterns in pediatric hematopoietic stem cell transplant patients and investigate their associations with mortality across multiple centers.
Design: Retrospective cohort between 2009 and 2014.
Setting: Twelve children's hospitals in the United States.
Extension study of participants from the trial of early aggressive therapy in juvenile idiopathic arthritis.
J Rheumatol
December 2014
From the Seattle Children's Hospital and Research Institute, Seattle, Washington; University of Utah, Pediatrics, Salt Lake City, Utah; Cleveland Clinic, Cleveland, Ohio; Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio; University of California at San Francisco, San Francisco, California; Duke University Medical Center, Pediatrics, Durham, North Carolina; Ohio State University and Nationwide Children's Hospital, Pediatrics, Columbus, Ohio; University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma; Steven and Alexandra Cohen Children's Medical Center of New York, New York; Stanford University School of Medicine, Palo Alto, California; Texas Scottish Rite Hospital, Dallas, Texas; Joseph M. Sanzari Children's Hospital at Hackensack University Medical Center, Hackensack, New Jersey, USA.C.A. Wallace, MD; S. Ringold, MD, MS, Seattle Children's Hospital and Research Institute; J. Bohnsack, MD, University of Utah; S.J. Spalding, MD, Cleveland Clinic; H.I. Brunner, MD, MSc, Cincinnati Children's Hospital Medical Center; D. Milojevic, MD, University of California at San Francisco; L.E. Schanberg, MD, Duke University Medical Center; G.C. Higgins, PhD, MD, Ohio State University and Nationwide Children's Hospital; K.M. O'Neil, MD, Oklahoma University Health Science Center, now at Riley Hospital for Children, Indianapolis, Indiana; B.S. Gottlieb, MD, MS, Steven and Alexandra Cohen Children's Medical Center of New York; J. Hsu, MD, MS, Stanford University School of Medicine; M.G. Punaro, MD, Texas Scottish Rite Hospital; Y. Kimura, MD, Joseph M. Sanzari Children's Hospital at Hackensack University Medical Center; A. Hendrickson, MPH, Seattle Children's Hospital and Research Institute.
Objective: To follow children with juvenile idiopathic arthritis (JIA) who had completed at least 6 months of the TRial of Early Aggressive Therapy (TREAT) clinical study for an additional 2 years, describing safety of early aggressive treatment, disease activity, function, and duration of clinical inactive disease (CID) during followup.
Methods: Children were treated as per provider's discretion. Physician, patient/parent, and laboratory measures of disease status as well as safety information were collected at clinic visits every 3 months for up to 2 years.
A review of pathogens causing lower respiratory tract infection in the pediatric hematopoietic stem cell transplant recipient.
J Pediatr Intensive Care
September 2014
Department of Pediatrics, Division of Critical Care Medicine, Joseph M Sanzari Children's Hospital at Hackensack University Medical Center, Hackensack, NJ, USA.
Pediatric hematopoietic stem cell transplant recipients are at risk for acquiring a variety of lower respiratory tract infections (LRTI), which result in frequent pediatric intensive care unit admission with high mortality. Recent advances in conditioning regimens, opportunistic infection prophylaxis, diagnostic tools, and treatment modalities have broadly impacted our understanding of LRTI among these vulnerable patients. In this review, the most common bacteria, viruses, and fungi causing LRTI in pediatric hematopoietic stem cell transplant patients are discussed.
View Article and Find Full Text PDFClinically inactive disease in a cohort of children with new-onset polyarticular juvenile idiopathic arthritis treated with early aggressive therapy: time to achievement, total duration, and predictors.
J Rheumatol
June 2014
From the Seattle Children's Hospital and Research Institute, Seattle, Washington; Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati; Cleveland Clinic, Cleveland, Ohio, USA; Department of Pediatrics, Shaare Zedek Medical Center, Jerusalem, Israel; Riley Hospital for Children, Indiana University School of Medicine, Indianapolis, Indianapolis; Rady Children's Hospital, San Diego, California; Duke University Medical Center, Durham, North Carolina; Children's Hospital of Boston; Department of Pediatrics, Floating Hospital for Children, Tufts Medical Center, Boston, Massachusetts; Department of Pediatrics, Texas Scottish Rite Hospital, Dallas, Texas; Hofstra North Shore-LIJ School of Medicine, New York, New York; Ohio State University and Nationwide Children's Hospital, Columbus, Ohio; Children's Hospital at Montefiore, New York, New York; Joseph M. Sanzari Children's Hospital at Hackensack University Medical Center, Hackensack, New Jersey, USA.C.A. Wallace, MD; S. Ringold, MD, MS, Seattle Children's Hospital and Research Institute; E.H. Giannini, MSc, DrPH; H.I. Brunner, MD, MSc, MBA, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine; S.J. Spalding, MD, Cleveland Clinic; P.J. Hashkes, MD, MSc, Shaare Zedek Medical Center; K.M. O'Neil, MD, Riley Hospital for Children, Indiana University School of Medicine; A.S. Zeft, MD, Cleveland Clinic; I.S. Szer, MD, Rady Children's Hospital; L.E. Schanberg, MD, Duke University Medical Center; R.P. Sundel, MD, Children's Hospital of Boston; D. Milojevic, MD, Floating Hospital for Children, Tufts Medical Center; M.G. Punaro, MD, Texas Scottish Rite Hospital; P. Chira, MD, Riley Hospital for Children, Indiana University School of Medicine; B.S. Gottlieb, MD, MS, Hofstra North Shore-LIJ School of Medicine; G.C. Higgins, PhD, MD, The Ohio State University and Nationwide Children's Hospital; N.T. Ilowite, MD, Children's Hospital at Montefiore; Y.
Objective: To determine the elapsed time while receiving aggressive therapy to the first observation of clinically inactive disease (CID), total duration of CID and potential predictors of this response in a cohort of children with recent onset of polyarticular juvenile idiopathic arthritis (poly-JIA).
Methods: Eighty-five children were randomized blindly to methotrexate (MTX), etanercept, and rapidly tapered prednisolone (MEP) or MTX monotherapy and assessed for CID over 1 year of treatment. Patients who failed to achieve intermediary endpoints were switched to open-label MEP treatment.
Phase-1 study of siplizumab in the treatment of pediatric patients with at least grade II newly diagnosed acute graft-versus-host disease.
Pediatr Transplant
March 2010
Pediatric Blood and Marrow Transplant Program, The Joseph M. Sanzari Children's Hospital at Hackensack University Medical Center, Hackensack, NJ 07601, USA.
In a phase-1 study, siplizumab, a humanized anti-CD2 monoclonal antibody, was administered (0.012 or 0.04 mg/kg) to 10 pediatric patients with > or = grade-II newly diagnosed, non-steroid-refractory aGvHD after BMT or PBSCT.
View Article and Find Full Text PDFTreatment of pain in juvenile idiopathic arthritis: a survey of pediatric rheumatologists.
Arthritis Rheum
February 2006
Joseph M. Sanzari Children's Hospital at Hackensack University Medical Center, 30 Prospect Avenue, Hackensack, NJ 07601, USA.
Objective: To assess the opinions and current practice of pediatric rheumatologists regarding treatment of chronic pain in children with juvenile idiopathic arthritis (JIA).
Methods: Standardized questionnaires were distributed to pediatric rheumatologists who are members of the Children's Arthritis and Rheumatology Research Alliance. Demographic data, opinions, and attitudes were solicited about pain assessment, current treatment of JIA with residual pain, and actual use of opioids to treat pain in children with JIA.
Coincidence of multiple endocrine neoplasia type IIa and type 1 diabetes mellitus.
J Pediatr Endocrinol Metab
September 2005
Genetics Service, Joseph M Sanzari Children's Hospital at Hackensack University Medical Center, Hackensack 07601, NJ.
Etanercept treatment in patients with refractory systemic onset juvenile rheumatoid arthritis.
J Rheumatol
May 2005
Joseph M. Sanzari Children's Hospital at Hackensack University Medical Center, Hackensack, New Jersey 07601, USA.
Objective: . To assess the efficacy and safety of etanercept in a large cohort of children with refractory systemic onset juvenile rheumatoid arthritis (SOJRA).
Methods: Standardized questionnaires were sent to US pediatric rheumatologists about patients with SOJRA treated with etanercept.