22 results match your criteria: "The Johns Hopkins Medical Institute.[Affiliation]"

The global social media response to the 14th annual Society of Cardiovascular Computed Tomography scientific sessions.

J Cardiovasc Comput Tomogr

September 2020

Division of Cardiovascular Medicine and Department of Radiology, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA.

The 2019 Society of Cardiovascular Computed Tomography (SCCT) Annual Scientific Meeting (ASM) was perhaps the most impactful meeting in recent memory for the field of cardiovascular CT. Beyond just being the highest attended ASM meeting in the society's history, the virtual impact of the meeting extended farther than ever before due to coordinated social media coverage and participation. As a result, the ASM reinforced the fact that the educational paradigm and audience of scientific meetings has changed.

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An Epithelioid Smooth Muscle Neoplasm Mimicking a Signet Ring Cell Carcinoma in the Ovary.

Int J Gynecol Pathol

September 2019

Department of Pathology, The Johns Hopkins Medical Institute, Baltimore, Maryland (D.X., A.A.B., C.L., A.R., R.V., B.M.R.).

A 53-yr-old woman who presented with elevated renal indices was discovered to have a 4.5 cm right renal mass and an incidental 9.7 cm left ovarian mass on imaging studies.

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Clinicopathologic Features and Genetic Alterations of a Primary Osteosarcoma of the Uterine Corpus.

Int J Gynecol Pathol

September 2019

Department of Pathology (G.Z., A.R., C.L., A.B., A.P., L.H., E.M., R.V., D.X.) Department of Gynecology and Obstetrics (R.L.S, R.V.), The Johns Hopkins Medical Institute, Baltimore, Maryland.

Primary osteosarcoma (OS) of the uterus is distinctly rare. We report a case of primary uterine OS with pulmonary metastasis in a 74-yr-old woman. Histopathologic features of the uterine tumor were in keeping with a pure chondroblastic OS composed of neoplastic cells with osteoblastic/chondroblastic differentiation and neoplastic bone formation.

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An immunocompetent mouse model of human glioblastoma.

Oncotarget

September 2017

Russel H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Orthotopic xenotransplantation studies represent the final stage in preclinical cancer research and could facilitate the implementation of precision medicine. To date, these xenografts have been tested in immunodeficient animals, but complete elimination of the adaptive immunity is a significant drawback. We present a method of efficient human glioblastoma (GBM) cell engraftment in adult mice with intact immune systems, mediated by a transient blockade of T-cell co-stimulation.

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The fate of radiology report recommendations at a pediatric medical center.

Pediatr Radiol

December 2017

Department of Radiology, Children's National Medical Center, 111 Michigan Ave. NW, Washington, DC, 20010, USA.

Background: The American College of Radiology (ACR) practice parameters for communication dictate that follow-up recommendations be suggested when appropriate. Radiologists assume that referring physicians read their reports and heed their advice. In reality, recommendations might not be carried out or even acknowledged.

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Atypical Proliferative (Borderline) Serous Tumor in the Brain: A Case Report.

Int J Gynecol Pathol

January 2018

Departments of Pathology (D.X., E.G.J., F.J.R., R.J.K.) Gynecology and Obstetrics (R.J.K) Oncology, The Johns Hopkins Medical Institute, Baltimore, MD (R.J.K.) Department of Pathology, Aurora St Luke's Medical Center, Milwaukee, WI (C.A.Z.).

A 59-year-old woman with a remote history of invasive ductal carcinoma of the breast was found on a follow-up computed tomography scan of her brain to have a 1-cm lesion in the right frontal lobe in 2008. In the ensuing years, before her current admission, multiple imaging studies of the brain revealed that the lesion was stable and it was, therefore, interpreted as a small area of encephalomalacia related to a thrombosed cortical vein, a cavernoma, or treated metastatic breast cancer. In 2013, the patient underwent a bilateral salpingo-oophorectomy for ovarian tumors that were diagnosed as bilateral serous cystadenofibromas.

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Background: Open aneurysm repair (OAR) remains the gold standard for treating ruptured thoracoabdominal aortic aneurysms (TAAAs). The aim of our study is to compare the 30-day postoperative outcomes among patients with ruptured TAAA undergoing OAR versus endovascular aneurysm repair.

Methods: Using the National Surgical Quality Improvement Program database (2006-2015), we identified patients who underwent OAR and endovascular repair for a ruptured TAAA.

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Microvascular Flaps in Nasal Reconstruction.

Facial Plast Surg

February 2017

Division of Facial Plastic and Reconstructive Surgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland.

Nasal reconstruction for subtotal and total rhinectomy defects is a challenging endeavor, which requires technical finesse, a keen artistic eye, and the ability to anticipate long-term changes that accompany postoperative healing. While local and regional flaps have traditionally been utilized to reconstitute missing nasal elements, certain situations may not provide sufficient or acceptable tissue for optimal reconstruction. In these situations, the three major components of the nose-lining, structural support, and external skin-may require reconstruction with tissues harvested from distant sites through microvascular free tissue transfer.

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Background and purpose Enlargement of the subarachnoid spaces in infancy (ESSI) is a common cause of macrocephaly without proven explanation. We have observed subarachnoid diffusion to be decreased in these patients. We aim to quantify the diffusivity of ventricular and subarachnoid cerebrospinal fluid in ESSI patients, to determine if diffusion characteristics deviate from normocephalic infants, and to propose a unique mechanism for ESSI.

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Background: Leigh disease is a metabolic disorder of the mitochondrial respiratory chain culminating in symmetrical necrotizing lesions in the deep gray nuclei or brainstem. Apart from classic gliotic/necrotic lesions, small-vessel proliferation is also characteristic on histopathology. We have observed lesional hyperperfusion on arterial spin-labeling (ASL) sequence in children with Leigh disease.

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Utility of five commonly used immunohistochemical markers TTF-1, Napsin A, CK7, CK5/6 and P63 in primary and metastatic adenocarcinoma and squamous cell carcinoma of the lung: a retrospective study of 246 fine needle aspiration cases.

Clin Transl Med

May 2015

The Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD 21287 USA ; Department of Pathology, The Johns Hopkins Medical Institute, Johns Hopkins Bayview Medical Center, Baltimore, MD 21224 USA.

Background: Fine needle aspiration (FNA) biopsy plays a critical role in the diagnosis and staging of lung primary and metastatic lung carcinoma. Accurate subclassification of adenocarcinoma (ADC) and/or squamous cell carcinoma (SqCC) is crucial for the targeted therapy. However, the distinction between ADC and SqCC may be difficult in small FNA specimens.

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Purpose: To characterize functional complaints of new low-vision rehabilitation patients.

Design: Prospective observational study.

Participants: The Low Vision Rehabilitation Outcomes Study recruited 819 patients between 2008 and 2011 from 28 clinical centers in the United States.

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Surface anatomy of the middle division of the facial nerve: Zuker's point.

Plast Reconstr Surg

February 2013

Baltimore, Md.; and Toronto, Ontario, Canada From The Johns Hopkins Medical Institute; the R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine; and The Hospital for Sick Children, University of Toronto.

Background: The anatomy of the facial nerve and its branches has been well documented. The course of the extratemporal facial nerve, its anatomical planes, and the surface landmarks of the temporal division and marginal mandibular division are well known. However, the surface landmark of the middle division of the facial nerve has not been studied to date.

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NOTES: current status and new horizons.

Gastroenterology

April 2012

Department of Medicine and Division of Gastroenterology and Hepatology, The Johns Hopkins Medical Institute, Baltimore, Maryland 21287, USA.

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Mullerianosis of the urinary bladder is a rare entity characterized by the presence of an admixture of at least two types of mullerian tissue in the muscularis propria of the bladder. We report a case of mullerianosis of the urinary bladder in a 28-year-old nulliparous woman with no history of pelvic surgery or endometriosis, and the diagnosis of mullerianosis was suggested initially in urine cytopathology report. In this study, previously reported cases of mullerianosis of urinary bladder are reviewed, and differential diagnosis of endometrial-like cells in the urine has been discussed.

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Cleft lip-cleft palate closure: the unknown contributions of Harvey Cushing.

Plast Reconstr Surg

October 2010

Baltimore, Md. From the Division of Plastic and Reconstructive Surgery and the Department of Neurosurgery, The Johns Hopkins Medical Institute.

Background: The development of surgical repair of cleft lip-cleft palate closure has been well documented in the literature. However, the contributions of an unlikely pioneer, Harvey Cushing, in the development of cleft lip-cleft palate closure have been to date unknown.

Methods: Patient surgical records from 1896 to 1912 at The Johns Hopkins Hospital documenting Harvey Cushing's cases were reviewed.

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Purpose: Laparoscopic Roux-en-Y gastric bypass is quickly replacing open techniques in the morbidly obese patient who presents for surgical treatment. Safety concerns about the laparoscopic technique have arisen in the literature with gastrojejunostomy leak rates of 5% or greater reported in several series.

Materials And Methods: A total of 251 consecutive gastric bypass operations were performed from August 2001 to January 2004 by a single surgeon with over 6 years' experience.

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Arkansas and the motorcyle helmet law.

J Ark Med Soc

June 2004

Department of Emergency Medicine, The Johns Hopkins Medical Institute, Baltimore, USA.

Motorcycle helmet laws have a long and colorful history dating back to the original work of Britain's Dr. Hugh Cairns during World War II. In Arkansas, the state's mandatory motorcycle helmet law was repealed in 1997 and replaced by a law requiring only those under the age of 21 to wear helmets.

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A 70-year-old man experienced an unusual disorder of visual perception after undergoing a ventriculoperitoneal shunt for normal-pressure hydrocephalus. The disorder was characterized by transient episodes of 90 degrees rotation of the visual environment, rather than the retinotopic visual field. This phenomenon is different from standard visual allesthesia and may have been caused by disordered integration of vestibular and visual inputs to the posterior parietal cortex or perseveration of a pre-existing environmental memory trace.

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