628 results match your criteria: "The John Paul II Catholic University[Affiliation]"

How sociodemographic factors relate to trust in artificial intelligence among students in Poland and the United Kingdom.

Sci Rep

November 2024

Institute of Sociological Sciences, Faculty of Social Sciences, The John Paul II Catholic University of Lublin, al. Raclawickie 14, 20-950, Lublin, Poland.

The article aims to determine the sociodemographic factors associated with the level of trust in artificial intelligence (AI) based on cross-sectional research conducted in late 2023 and early 2024 on a sample of 2098 students in Poland (1088) and the United Kingdom (1010). In the times of AI progressively penetrating people's everyday life, it is important to identify the sociodemographic predictors of trust in this increasingly dynamically developing technology. The theoretical framework for the article is the extended Unified Theory of Acceptance and Use of Technology (UTAUT), which highlights the significance of sociodemographic variables as predictors of trust in AI.

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Influence of Heat Treatment of Nitinol Wire on the Properties of Nitinol/Hybrid Layer for Ibuprofen Release.

Molecules

November 2024

Faculty of Science and Technology, A. Chełkowski Institute of Physics, University of Silesia in Katowice, 75 Pulku Piechoty 1A, 41-500 Chorzow, Poland.

The efficiency of drug delivery from coatings of metallic implants is one of the key factors. The influence of chemical and thermal treatments of nitinol wire on the corrosion properties, deposition of hydroxyapatite(HA)/poly ε-caprolactone-polyethylene glycol (PEG--PCL), and the amount of ibuprofen released from that bilayer were studied. The hydroxyapatite layer was electrodeposited by pulse current, while the PEG--PCL layer was by drop-coating.

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Application of Human Plasma Targeted Lipidomics and Analysis of Toxic Elements to Capture the Metabolic Complexities of Hypothyroidism.

Molecules

October 2024

Associated Laboratory for Green Chemistry (LAQV) of the Network of Chemistry and Technology (REQUIMTE), Department of Chemical Sciences, Laboratory of Applied Chemistry, Faculty of Pharmacy, University of Porto, 50-313 Porto, Portugal.

Background: Hypothyroidism (HT) affects millions worldwide and can lead to various lipid disorders. The metabolic complexity and the influence of toxic elements in autoimmune and non-autoimmune HT subtypes are not fully understood. This study aimed to investigate the relationships between plasma lipidome, toxic elements, and clinical classifications of HT in unexposed individuals.

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One of the challenges of the pharmaceutical and cosmetic industries is to deliver biochemical compounds that can be advantageous for the skin. Research on Boraginaceae taxa has confirmed their use in traditional medicine and proved the potential biological importance of various molecules in cosmetology. The main classes of valuable compounds associated with Boraginaceae taxa are fatty acids, including γ-linolenic acid, essential oils, phenolic acids (e.

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and microalgae are a rich source of pro-health metabolites (% d.m.): proteins (50.

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Wind farms are still developing dynamically worldwide, with promising prospects for further growth. Therefore, the assessment of their impact on animals has been carried out. So far, few studies have been conducted on game mammals, and their results are divergent.

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Article Synopsis
  • The article describes the validation process of a research tool designed to measure healthcare professionals' attitudes toward immigrant patients.
  • The validation occurred in two phases: first, assessing the content validity with expert judges, and second, testing the questionnaire's reliability and validity among 340 healthcare professionals.
  • Results showed that the tool has strong psychometric properties, making it useful for evaluating attitudes and supporting educational initiatives.
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Extreme environments, such as highly saline ecosystems, are characterised by a limited presence of microbial communities capable of tolerating and thriving under these conditions. To better understand the limits of life and its chemical and microbiological drivers, highly saline and brine groundwaters of Na-Cl and Na-Ca-Cl types with notably diverse SO contents were sampled in water intakes and springs from sedimentary aquifers located in the Outer Carpathians and the Carpathian Foredeep basin and its basement in Poland. Chemical and microbiological methods were used to identify the composition of groundwaters, determine microbial diversity, and indicate processes controlling their distribution using multivariate statistical analyses.

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The population of Poland could be of particular interest to researchers studying religion and spirituality. Catholicism has played a significant role in shaping the country's culture, history, and tradition and is considered a national religion. More recently, however, the processes of moving away from regular participation in religious services and loosening ties with the institution of the Catholic Church are marked (Polish Public Opinion Research Center, CBOS).

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Kynurenic acid (KYNA) is a metabolite of tryptophan formed on the kynurenine pathway. Its pharmacological effects are relatively well characterized in mammals, whereas its role in fish is poorly understood. Therefore, the aim of the study was to expand the knowledge of KYNA's presence inside a fish's body and its impact on fish development and function.

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Application of proteomics for novel drug discovery and risk prediction optimisation in stroke and myocardial infarction: a review of in-human studies.

Drug Discov Today

November 2024

Department of Twin Research, King's College London, London, UK; Medical Research Council Population Health Research Unit, University of Oxford, Oxford, UK; Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK. Electronic address:

The use of proteomics in human studies investigating stroke and myocardial infarction (MI) has been increasing, prompting a review of the literature. This revealed proteinaceous biomarkers of stroke from thrombi, brain tissue, cells, and particles, some of which cross the blood-brain barrier (BBB). Several proteins were also implicated in coronary artery disease (CAD), which often underlies MI, cholesterol transportation, and inflammation.

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Removal of polyphenols from anthocyanin-rich extracts using 4-vinylpyridine crosslinked copolymers.

Food Chem

January 2025

Department of Chemistry, Institute of Biological Sciences, Faculty of Medicine, Collegium Medicum, The John Paul II Catholic University of Lublin, Konstantynów 1J, 20-708 Lublin, Poland. Electronic address:

In this work, new sorbents for the purification of anthocyanin-rich extracts were evaluated. Copolymers of 4-vinylpyridine crosslinked with trimethylolpropane trimethacrylate (poly(4VP-co-TRIM)) or 1,4-dimethacryloyloxybenzene (poly(4VP-co-14DMB)) were tested for their potential to capture polyphenols. Copolymers were obtained by seed swelling polymerization in the form of microspheres with permanent porous structure - attractive features of sorbents used for sample purification by dispersive solid phase extraction.

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Article Synopsis
  • Plants contain a wide variety of secondary metabolites, with phenolic compounds being the most prevalent; over 8000 types of polyphenols have been identified, including phenolic acids, flavonoids, and lignans.
  • Acne, particularly acne vulgaris and rosacea, is one of the most commonly treated skin conditions, yet there's limited research on how plant phenolics can help in its treatment.
  • The review reveals that phenolic compounds, known for their antibacterial, anti-inflammatory, and antioxidant properties, may be effective in treating acne, especially when combined with standard medications; compounds like EGCG, quercetin, and nobiletin show promise, although more clinical studies are needed to confirm their effectiveness.
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Do aluminum, boron, arsenic, cadmium, lipoperoxidation, and genetic polymorphism determine male fertility?

Ecotoxicol Environ Saf

October 2024

Nicholaus Copernicus University, Collegium Medicum in Bydgoszcz, Department of Medical Biology and Biochemistry, M. Karłowicz St. 24, Bydgoszcz PL 85-092, Poland. Electronic address:

Male infertility is a world multifactorial problem modulated by environmental and genetic factors. Male aspects account for 20-50 % of infertility cases. Our results are unique because they treat the importance of components participating in the determination of male infertility (environmental and immunogenetic determinants, seminological analysis, lipoperoxidation, genetic determinants, role of aluminum, arsenic, cadmium and boron).

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Omega-3 Polyunsaturated Fatty Acids in Depression.

Int J Mol Sci

August 2024

Department of Clinical Pharmacy and Pharmaceutical Care, Medical University of Lublin, Chodźki Street 7, 20-093 Lublin, Poland.

Omega-3 polyunsaturated fatty acids have received considerable attention in the field of mental health, in particular regarding the treatment of depression. This review presents an overview of current research on the role of omega-3 fatty acids in the prevention and treatment of depressive disorders. The existing body of evidence demonstrates that omega-3 fatty acids, in particular eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have antidepressant effects that can be attributed to their modulation of neuroinflammation, neurotransmitter function, and neuroplasticity.

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Religious struggles tend noticeably to influence the sphere of social well-being in emerging adulthood as individuals modify their religious beliefs and practices, form personal identity patterns, and rediscover new life purpose and values. The aim of the current study was to investigate whether meaning-making and meaning in life (presence and search) can serially mediate the hypothesized links between religious comfort vs. strain and social well-being.

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Facebook is one of the most popular social networking sites. However, Facebook intrusion or addiction is a growing concern as it involves an excessive attachment to Facebook, which disrupts daily functioning. To date, few studies have examined whether cross-cultural differences in the measurement of Facebook addiction exist.

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Some students suffer from math anxiety and experience negative emotions in mathematics education. Children's math anxiety is negatively related to their math achievement, suggesting that math anxiety puts their math learning at risk. Several theoretical accounts have been proposed that help to explain this association between math anxiety and achievement.

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A novel library of naphthoquinone derivatives (3-5 aa) was synthesized and evaluated for their anticancer properties. Specifically, compounds 5 i, 5 l, 5 o, 5 q, 5 r, 5 s, 5 t, and 5 v demonstrated superior cytotoxic activity against the cancer cell lines that were studied. All the studied compounds exhibited a higher selectivity index (SI) and a favourable safety profile than the standard drug doxorubicin.

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4-Vinylpyridine copolymers for improved LC-MS tryptophan and kynurenine determination in human serum.

Sci Rep

August 2024

Department of Chemistry, Institute of Biological Sciences, Faculty of Medicine, the John Paul II Catholic University of Lublin, Konstantynów 1J, 20-708, Lublin, Poland.

Article Synopsis
  • Tryptophan and its metabolite kynurenine are important for various biological processes, sparking interest in their detection methods in biological samples.
  • This study highlights the effectiveness of two specially designed polymers for cleaning human serum, specifically poly(4VP-co-TRIM), which effectively reduces interference during the measurement of tryptophan and kynurenine using liquid chromatography-mass spectrometry (LC-MS).
  • Results showed that poly(4VP-co-TRIM) achieved good recovery rates (76% for tryptophan and 87% for kynurenine) and outperformed some common commercially available sorbents in minimizing matrix effects.
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Purpose: This study aims to adapt and verify the psychometric properties of the Craving for Internet Gaming Scale (CIGS) in a Polish sample. Craving, although observed as significantly associated with Internet Gaming Disorder, is not currently included in its diagnostic criteria. This research addresses the need for scales to measure craving in this particular context.

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Article Synopsis
  • The cult of saints in Western Europe emerged during late antiquity and the early Middle Ages, where they played a crucial role in providing medical hope to people who lacked access to doctors.
  • People prayed to specific saints for healing, leading to the emergence of "specialized" saints who were believed to treat different skin issues and wounds.
  • Research explored the connection between the cult of saints and the establishment of hospitals, focusing on saints related to skin diseases, including patrons of animal bites, wounds, and contagious diseases like leprosy and scabies.
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