2 results match your criteria: "The John's Hopkins University School of Medicine and Whiting School of Engineering[Affiliation]"
IEEE Open J Eng Med Biol
February 2024
Bessie Darling Massey Professor and Director, Department of Biomedical Engineering, Co-Director, Kavli Neuroscience Discovery InstituteJohns Hopkins University School of Medicine and Whiting School of Engineering Baltimore MD 21218 USA.
Over the past two decades Biomedical Engineering has emerged as a major discipline that bridges societal needs of human health care with the development of novel technologies. Every medical institution is now equipped at varying degrees of sophistication with the ability to monitor human health in both non-invasive and invasive modes. The multiple scales at which human physiology can be interrogated provide a profound perspective on health and disease.
View Article and Find Full Text PDFProg Biophys Mol Biol
April 2006
Center for Cardiovascular Bioinformatics and Modeling, The John's Hopkins University School of Medicine and Whiting School of Engineering, Baltimore, MD, USA.
Calcium-induced-calcium-release in cardiac myocytes is the release of Ca(2+) from the sarcoplasmic reticulum (SR) triggered by Ca(2+) entering the cell through L-type Ca(2+) channels. The Ca(2+) is released through ryanodine receptors which 'sense' local [Ca(2+)] in the small region (the diadic space) positioned between the t-tubules and the SR. The length-scale of a single diad is of the order of 10nm and the diffusion time-scale is of order of 1 micros with each cell containing approximately 10,000 diadic spaces which act independently.
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