1 results match your criteria: "The James L. Winkle College of Pharmacy and College of Medicine[Affiliation]"
Stability of the nitrogen mustard mechlorethamine in novel formulations for dermatological use.
Int J Pharm
October 2008
University of Cincinnati Medical Center, The James L. Winkle College of Pharmacy and College of Medicine, Department of Pharmacology and Cell Biophysics, 3223 Eden Ave., ML 0004, Cincinnati, OH 45267, USA.
Long term stability measurements were made for the nitrogen mustard mechlorethamine HCl at a concentration of 0.02% in six topical formulations: Aquaphor ointment, Transcutol, Labrasol, 10% Transcutol in Aquaphor, 10% Transcutol in Labrasol, and Aquaphilic ointment. The drug decomposed gradually in Aquaphor ointment at room temperature, dropping to 95% in 4 weeks, 85% in 12 weeks, and 78% in 39 weeks.
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