441 results match your criteria: "The Institute of Child Health[Affiliation]"
Congenital heart disease and thyroid dysfunction in Down syndrome reported at Children`s Hospital, Lahore, Pakistan.
Turk J Pediatr
August 2020
Departments of Pediatric Cardiology, The Children's Hospital and the Institute of Child Health, Lahore, Pakistan.
Article Synopsis
- The study by Yaqoob et al. focuses on the prevalence of congenital heart disease and thyroid dysfunction in children with Down syndrome at a children's hospital in Lahore, Pakistan.
- A total of 350 children with Down syndrome were analyzed, revealing that 41.8% had congenital heart defects, primarily ventricular septal defects, while 22% experienced thyroid dysfunction, including 5.9% with hypothyroidism.
- The findings highlight the importance of early diagnosis and treatment for these comorbidities to improve health outcomes and reduce complications in affected children.
"The problem is people don't know how to talk to you:" How Medicaid recipients understand and use health plan report cards and instruction sheets.
Health Mark Q
May 2019
b Health Outcomes & Biomedical Informatics and the Institute of Child Health Policy , University of Florida, Gainesville , Florida , USA.
Article Synopsis
- The study wanted to learn how low-income, diverse people understand and feel about health plan information from Medicaid report cards.
- They held 22 discussions with people from different ethnic backgrounds in cities and rural areas.
- Many found the information confusing, especially because there was too much irrelevant stuff, but using clear visuals helped them understand better.
Bacterial contamination of Pakistani currency notes from hospital and community sources.
Pak J Med Sci
January 2018
Muhammad Zubair, M.Phil, Department of Microbiology, The Children's Hospital and The Institute of Child Health, Ferozepur Road, Lahore, Pakistan.
Objective: We determined the bacterial contamination and antibiotic resistance profile of circulating Pakistani currency notes collected from hospital and community sources.
Methods: This prospective study was organized from July to December 2015 in the Microbiology Department of The Children's Hospital and The Institute of Child Health Lahore. It was done on one hundred currency notes of four different denominations collected from various groups of people in sterile polythene bags.
Clinical features and outcome in paediatric newly diagnosed immune thrombocytopenic purpura in a tertiary care centre.
Pak J Med Sci
January 2018
Shazia Riaz, MD. Department of Paediatric Haematology, Oncology and Bone Marrow Transplant, The Children's Hospital and the Institute of Child Health, Lahore, Pakistan.
Objective: The study aimed to demonstrate the pattern of clinical presentations and outcome of acute Immune Thrombocytopenia (ITP) in our Centre.
Methods: A descriptive, observational study was conducted by collecting and analysing the data of 103 patients of acute ITP, ageing between 1-14 years, at The Children's Hospital, Lahore from January 2016 to December 2016. We collected the data regarding age, sex, clinical presentations, history of preceding viral infections, vaccination history, laboratory values, different treatment options used, and response to the treatment concerning complete response, partial response and poor responders.
Factors contributing to the lack of interest in research activities among postgraduate medical students.
Pak J Med Sci
January 2018
Prof. Rehan Ahmed Khan, MBBS, FCPS, FRCS, JM-HPE, M.Sc. HPE. Professor of Surgery, Islamic International Medical College, Riphah International University, Islamabad, Pakistan.
Objective: To determine the factors contributing to lack of interest in research activities among postgraduate residents in pediatric medicine.
Methods: This cross-sectional survey was conducted at The Children's Hospital Lahore, Pakistan in August 2017. The questionnaire was distributed to 105 postgraduate residents working in pediatric medicine department and 90 of them returned the completed proforma (response rate; 86%).
Hearing impairment after acute bacterial meningitis in children.
Pak J Med Sci
January 2018
Dr. Fauzia Saeed, MSC Audiology, Department of Audiology, The Children's Hospital and The Institute of Child Health, Lahore, Pakistan.
Objective: To determine the incidence of hearing loss after acute episode of meningitis in children.
Methods: A descriptive study carried out in the Department of Pediatric Medicine of The Children's Hospital Lahore, Pakistan from January 2014 to July 2016. A total of 175 children one month to 13 years of age admitted with diagnosis of meningitis were included.
Spectrum of Joint Deformities in Children with Juvenile Idiopathic Arthritis.
J Coll Physicians Surg Pak
June 2018
Department of Paediatric Medicine, Children's Hospital and The Institute of Child Health, Lahore.
Objective: To determine the frequency and types of joint deformities in children with juvenile idiopathic arthritis and their association with clinical parameters and rheumatoid factor.
Study Design: Cross-sectional study.
Place And Duration Of Study: Rheumatology Outpatient Clinic, the Children's Hospital and the Institute of Child Health, Lahore, from September 2014 to February 2015.
Berardinelli-Seip Congenital Generalised Lipodystrophy.
J Coll Physicians Surg Pak
May 2018
Department of Pediatric Gastroenterology and Hepatology, The Children's Hospital and The Institute of Child Health, Lahore.
Berardinelli-Seip congenital lipodystrophy (BSCL) syndrome is a rare genetic disorder caused by dysregulation of glycemic and lipid metabolism. We report five BSCL cases with typical clinical pictures and complications. These, to the best of our knowledge, represent the first case series from Pakistan.
View Article and Find Full Text PDFComparison of volume and frequency advancement feeding protocols in very low birth weight neonates.
Pak J Med Sci
January 2018
Dr. Nazia Fatima, FCPS (Paeds Med), Trainee, Children Hospital Complex and the Institute of Child Health, Multan, Pakistan.
Objective: To determine the outcomes in very low birth weight (VLBW) neonates receiving volume advancement versus frequency advancement feeding protocols.
Methods: This controlled clinical trial was conducted in Children Hospital Multan within duration of 6 months from February 2017 to August 2017. VLBW neonates having weight < 1500 g at the time of birth were included.
Postgraduate residents' perception of the clinical learning environment; use of postgraduate hospital educational environment measure (PHEEM) in Pakistani context.
J Pak Med Assoc
March 2018
Department of Paediatric Medicine, The Children's Hospital and The Institute of Child Health, Lahore.
Objective: To evaluate the perception of postgraduate residents about the clinical educational environment and to investigate the association of their perception with different specialities and years of residency.
Methods: The study was conducted in August 2016 at The Children's Hospital, Lahore, Pakistan, and comprised postgraduate residents who were asked to complete postgraduate hospital educational environment measure questionnaire. The residents' individual perception scores were calculated and the means of both individual domain and global score of the questionnaire were compared by different specialities and different levels of residency training year.
Validation of serum C-reactive protein for the diagnosis and monitoring of antibiotic therapy in neonatal sepsis.
Pak J Med Sci
January 2017
Dr. Muhammad Asghar Ali (FCPS Pediatrics), Senior Registrar Neonatology, Children Hospital Complex and the Institute of Child Health, Multan, Pakistan.
Objective: To evaluate the adequacy of serum C-reactive protein (CRP) in diagnosing neonatal sepsis and role of CRP in determining the duration of antibiotic treatment in neonatal sepsis.
Methods: In this validation study, we included 135 neonates with suspected diagnosis of sepsis within duration of nine months from September 2016 to May2017 in Children Hospital Multan. Blood samples were drawn from every neonate for culture sensitivity and measurement of serum C-reactive proteins.
Analyzing communication skills of Pediatric Postgraduate Residents in Clinical Encounter by using video recordings.
Pak J Med Sci
January 2017
Ahsan Waheed Rathore, DCH, MRCP, MRCPCH, FRCP. Professor of Pediatric Medicine, Department of Pediatric Medicine, The Children's Hospital and The Institute of Child Health, Lahore, Pakistan.
Objective: To analyze communication skills of pediatric postgraduate residents in clinical encounter by using video recordings.
Methods: This qualitative exploratory research was conducted through video recording at The Children's Hospital Lahore, Pakistan. Residents who had attended the mandatory communication skills workshop offered by CPSP were included.
Stress, seizures, and epilepsy: Patient narratives.
Epilepsy Behav
March 2018
Epilepsy Center, Department of Neurology, Friedrich-Alexander-University Erlangen-Nuremberg, Germany. Electronic address:
In epilepsy, individual seizures can be triggered by a variety of external and internal stimuli. One of the most common trigger factors reported by patients is stress. However prevalent, stress-related triggering of episodes seems underappreciated in epilepsy for various reasons, and its misinterpretation often leads to other diagnoses, e.
View Article and Find Full Text PDFObjective: To determine the clinical presentations and outcomes of the children suffering from tuberculous meningitis.
Methods: This prospective, descriptive study was conducted at the Children's Hospital and the Institute of Child Health, Multan, Pakistan, from February to December 2015. The Pakistan Paediatric Association scoring chart for tuberculosis was used as a tool for the probable diagnosis.
Leptin Replacement Reestablishes Brain Insulin Action in the Hypothalamus in Congenital Leptin Deficiency.
Diabetes Care
April 2018
Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Center Munich at the University of Tübingen, German Center for Diabetes Research, Tübingen, Germany.
Objective: Human obesity is associated with impaired central insulin signaling, and in very rare cases, severe obesity can be caused by congenital leptin deficiency. In such patients, leptin replacement results in substantial weight loss and improvement in peripheral metabolism.
Research Design And Methods: In a leptin-deficient patient, we investigated the impact of leptin substitution on central insulin action, as quantified by changes in neuronal activity after intranasal insulin application.
Reasons Of Self-Discharge From Nursery Of A Tertiary Care Hospital.
J Ayub Med Coll Abbottabad
July 2018
Department of Histopathology, CMH, Rawalpindi, Pakistan.
Background: Patients who leave against medical advice (LAMA) from a health facility is a recognized problem. In neonatology practice this issue is particularly sensitive as repercussions can be severe. The purpose of this study was to evaluate the factors influencing the decision of parents to self-discharge their babies against medical advice.
View Article and Find Full Text PDFGastric teratoma: Our 17 year experience.
J Pediatr Surg
February 2018
Department of Pediatric Surgery, The Children's Hospital and the Institute of Child Health, Lahore.
Background: Teratomas originating from the stomach are extremely rare and account for less than 1% of all cases of teratomas. This site of occurrence has unique diagnostic and management issues.
Methods: A single centre case-record review of gastric teratomas presenting between January 2000 and April 2017 was performed.
Patient safety awareness among postgraduate students and nurses in a tertiary health care facility.
Pak J Med Sci
January 2017
Dr. Ahsan Waheed Rathore, MBBS, DCH, MRCP, MRCPCH, FRCP. Professor of Pediatric Medicine, Department of Paediatric Medicine, The Children's Hospital and The Institute of Child Health, Lahore, Pakistan.
Objective: To determine the knowledge of patient safety among postgraduate residents (PGR) and nurses in a tertiary care hospital.
Methods: This casual comparative study was conducted among the postgraduate residents and nurses working at The Children's Hospital Lahore in the month of July, August 2017. Both PGR and nurses were asked to complete APSQ-IV questionnaire about patient safety on 7 point Likert scale.
Congenital Cytomegalovirus: A European Expert Consensus Statement on Diagnosis and Management.
Pediatr Infect Dis J
December 2017
From the *Paediatric Infectious Diseases Research Group, St George's University, London, United Kingdom; †Centre for Virology, University College Medical School, London; ‡Kingston Hospital NHS Foundation Trust, London, United Kingdom; §The Hague Medical Center (HMC), Department of Pediatrics and Sophia Children's hospital, Erasmus Medical Center Rotterdam Department of Pediatric Infectious Diseases; ¶Pediatric Infectious Diseases Unit, Hospital Universitario 12 de Octubre, Universidad Complutense, Instituto de Investigación Hospital 12 de Octubre, Madrid, Spain; ∥Center for Chronic Immunodeficiency and Center for Pediatrics and Adolescent Medicine, Medical Center and Faculty of Medicine, University of Freiburg, Germany; **Our Lady's Children's Hospital Crumlin, UCD School of Medicine and Health Sciences, Dublin, Ireland; ††Department of Obstetrical, Gynaecological and Paediatric Sciences, Operative Unit of Neonatology, Polyclinic St. Orsola-Malpighi, University of Bologna, Bologna, Italy; ‡‡Pediatric Infectious Diseases, Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain; §§Department of Paediatrics, The University of Melbourne & Murdoch Children's Research Institute, Royal Children's Hospital Melbourne, Parkville, Australia; ¶¶NICU and Neonatal Unit, Fondazione IRCCS Policlinico S. Matteo, Pavia, Italy; ∥∥Infectious Diseases Unit, 3rd Department of Pediatrics, Faculty of Medicine, Aristotle University School of Health Sciences, Thessaloniki, Greece; ***Great Ormond Street Children's Hospital, London, and the Institute of Child Health, UCL, London, United Kingdom; †††NICU and Neonatal Unit, Fondazione IRCCS Policlinico S. Matteo, Pavia, Italy; ‡‡‡Imperial College NHS Healthcare, London, United Kingdom; §§Pediatric Infectious Diseases, Children's Hospital, University of Helsinki and Helsinki University Hospital, Finland; ¶¶¶Department of Pediatric Infectious Diseases, Emma Children's Hospital, Academic Medical Center, Amsterdam, The Netherlands; ∥∥∥National and Kapodistrian University of Athens, Greece; ****Children's Hospital of Geneva, University Hospitals of Geneva, Switzerland; ††††Pediatric Infectious Diseases Unit, Gregorio Marañón Hospital, Madrid, Spain; and ‡‡‡‡Department of Medical Microbiology, Leiden University Medical Center, Leiden, The Netherlands.
A 3' untranslated region polymorphism rs2304277 in the DNA repair pathway gene OGG1 is a novel risk modulator for urothelial bladder carcinoma.
Ann Hum Genet
March 2018
Department of Biosciences, COMSATS Institute of Information Technology, Islamabad, Pakistan.
Article Synopsis
- This study investigates how changes in DNA repair genes may influence the risk of developing urothelial bladder carcinoma (UBC), revealing significant associations with specific gene polymorphisms.
- Researchers genotyped a group of 200 UBC patients and 200 controls, finding that OGG1 rs2304277 and XPC rs2228001 are linked to a higher likelihood of developing the disease.
- The findings suggest increased risks for both smokers and nonsmokers, as well as for different tumor grades, highlighting the significance of these genetic variants in UBC susceptibility, particularly in the Pakistani population.
Phenotypic characterization of extended-spectrum-beta-lactamase producing from healthy individuals, patients, sewage sludge, cattle, chickens and raw meat.
Pak J Med Sci
January 2017
Ahsan Waheed Rathore, MRCPCH, FRCP, Department of Paediatric Medicine, The Children's Hospital and The Institute of Child Health, Lahore, Pakistan.
Objective: The present study aimed to determine the frequency and antimicrobial profile of ESBL-producing isolates of in different environments.
Methods: This cross-sectional study was conducted at The Children's Hospital and The Institute of Child Health, Lahore from July to December 2015. The faecal specimens from healthy individuals, patients, sewage sludge, cattle, chickens and raw meat (n = 122) were processed for microbiological analysis using MacConkey agar supplemented with cefotaxime.
Objective: To evaluate the effectiveness of pulse oximetry as a screening tool for critical congenital heart defects in newborns.
Methods: This cross-sectional study was conducted at the neonatology department of the Children's Hospital and the Institute of Child Health, Lahore, Pakistan, from January to June 2016, and comprised neonates aged up to 07 days. Babies with a prenatal diagnosis of heart defects and those whose parents refused to give consent were excluded.
Effectiveness and Safety of Sofosbuvir in Treatment-NäiveChildren with Hepatitis C Infection.
J Coll Physicians Surg Pak
July 2017
Department of Paediatric Gastroenterology and Hepatology, The Children's Hospital and The Institute of Child Health, Lahore.
Objective: To determine the effectiveness and safety of Sofosbuvir and Ribavirin combination in treatment-näivechildren with HCV infection.
Study Design: An experimental study.
Place And Duration Of Study: Gastroentrology, Hepatology Department, The Children's Hospital and The Institute of Child Health, Lahore, from January to December 2016.
Mutation Spectrum and Genotype-Phenotype Analyses in a Pakistani Cohort With Hemophilia B.
Clin Appl Thromb Hemost
July 2018
1 Hematology Department, Institute of Basic Medical Sciences, Khyber Medical University, Peshawar, Pakistan.
This study aimed to (1) identify F9 genetic alterations in patients with hemophilia B (HB) of Pakistani origin and (2) determine the genotype-phenotype relationships in these patients. Diagnosed cases of HB were identified through registries at designated tertiary health-care centers across the country. Consenting patients were enrolled into the study.
View Article and Find Full Text PDFSpontaneous Perforation Of Bile Duct, Clinical Presentation, Laboratory Work Up, Treatment And Outcome.
J Ayub Med Coll Abbottabad
December 2017
Department of Paediatric Gastroenterology Hepatology, The Children's Hospital & the Institute of Child Health, Lahore, Pakistan.
Background: Spontaneous perforation of bile duct (SPBD) is a rare and often misdiagnosed entity. Though rare, it is the second most common surgical cause of jaundice in infants, after biliary atresia. This study was planned to determine the clinical presentation, study different diagnostic modalities, treatment and outcome of patients with spontaneous perforation of bile duct.
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