3 results match your criteria: "The Institute of Cancer Research and Royal Marsden Foundation Trust[Affiliation]"

Objectives: To investigate whether MRI-based measurements of fibro-glandular tissue volume, breast density (MRBD), and background parenchymal enhancement (BPE) could be used to stratify two cohorts of healthy women: BRCA carriers and women at population risk of breast cancer.

Methods: Pre-menopausal women aged 40-50 years old were scanned at 3 T, employing a standard breast protocol including a DCE-MRI (35 and 30 participants in high- and low-risk groups, respectively). The dynamic range of the DCE protocol was characterised and both breasts were masked and segmented with minimal user input to produce measurements of fibro-glandular tissue volume, MRBD, and voxelwise BPE.

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Objective: To present and evaluate an automated method to correct scaling between Dixon water/fat images used in breast density (BD) assessments.

Methods: Dixon images were acquired in 14 subjects with different weightings (flip angles, FA, 4°/16°). Our method corrects intensity differences between water () and fat () images via the application of a uniform scaling factor (SF), determined subject-by-subject.

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