11 results match your criteria: "The Institute of Basic Theory[Affiliation]"

Article Synopsis
  • Scutellaria baicalensis and Coptis chinensis are traditional herbal medicines used to treat hyperlipidemia, but their combined effects and mechanisms are not fully understood.
  • This study aims to investigate how these herbs work together to combat high lipid levels in the blood through a series of experiments, including dietary modeling and various laboratory analyses.
  • The results indicate that the combination of berberine and baicalin significantly lowers harmful cholesterol levels and alters gene expression related to fatty acid breakdown in the liver, pointing to a promising herbal treatment for hyperlipidemia.
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Objective: To evaluate the clinical efficacy of Traditional Chinese Medicine prescriptions for resolving phlegm in the treatment of angina pectoris of phlegm-stasis coronary heart disease by a network Meta-analysis.

Methods: Randomized controlled trials (RCTs) on clinical efficacy of CHD angina pectoris with interaction of phlegm and blood stasis were searched in PubMed, Springer, the Cochrane Library and Chinese-language databases China National Knowledge Infrastructure, China Science and Technology Journal Database, and Wanfang Data from their inception to December 2021. Literature was screened and literature bias risk was assessed by RevMan5.

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Qishen granules regulate intestinal microecology to improve cardiac function in rats with heart failure.

Front Microbiol

June 2023

Zang-xiang Teaching and Research Department, The Institute of Basic Theory for Chinese Medicine, China Academy of Chinese Medical Sciences, Beijing, China.

Introduction: Qishen Granule (QSG), a clinically approved traditional Chinese medicine, has been researched for treating heart failure (HF) for many years. However, the effect of QSG on intestinal microecology remains unconfirmed. Therefore, this study aimed to elucidate the possible mechanism of QSG regulating HF in rats based on intestinal microecological changes.

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Objective: To analyze the Doppler ultrasound blood flow of Renying (carotid artery) pulse, Cunkou (radial artery) pulse, and Fuyang (anterior tibial artery) pulse in the normal group and the functional constipation with gastrointestinal heat (FCGH) group, and to compare and explore the differences of Renying, Cunkou and Fuyang pulses.

Methods: Sixty normal subjects and 60 patients with gastrointestinal heat constipation were collected in the department of ultrasound, Beijing Anzhen Hospital, Capital Medical University. Doppler ultrasound was used to observe the blood flow indexes including maximum systolic velocity (Vp), maximum diastolic velocity (Vd), mean velocity (Vm), pulse index (PI), resistance index (RI), vascular diameter (D), and circulation blood flow cycle (ET) of Renying pulse, Cunkou pulse and Fuyang pulse in the normal group and patients with gastrointestinal heat constipation.

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Ethnopharmacological Relevance: Rheumatoid arthritis (RA) is a common systemic autoimmune disease with high morbidity and disability rate. Currently, there is no effective allopathic treatment for RA, and most of the drugs provoke many adverse effects. Simiao Yong'an decoction (SMYAD) is a traditional Chinese prescription for the treatment of sore and gangrene caused by hot poison.

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Objective: To investigate the distribution of monocyte subpopulations and the changes of Toll-like receptor 4 (TLR4), CD163 and CD36 expressions in the peripheral blood of patients with hyperlipidemia of phlegm-stagnancy obstruction syndrome pattern (HLE-PSO), and to evaluate the intervening effects of Qutan Huayu Jiedu (QHJ) herbs on these parameters.

Methods: Monocytes in the peripheral blood were sorted using flow cytometry into 3 subpopulations: the CD14high CD16- (Mo1), the CD14high CD16+ (Mo2a) and the CD14low CD16+ (Mo2b) subpopulation. The percentages of various monocyte subpopulations in 83 patients and 42 matched healthy controls were determined and the levels of their surface receptors TLR4, CD163 and CD36 expressions were assayed with flow cytometer.

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Objective: To investigate the differential plasma protein profiles in patients with hyperlipidemia & atherosclerosis (H&A) of different patterns of phlegm-stasis syndrome (PSS) for seeking their biomarker proteins.

Methods: Two-dimensional gel electrophoresis and gel screening graphical analysis were performed on plasma proteins got from 146 patients; corresponding protein spots were fetched from the gel for two-stage mass-spectrometric analysis by quadruple time-of-flight mass spectrometry; then the differential proteins for PSS were discriminated by Fisher discriminate analysis.

Results: Excepting two uncertain proteins, 7 differential proteins were screened out from the 11 differentially expressed plasma protein spots with variability over 100% in the inter-block matching.

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Objective: To study the new chemical constituents from Radix Polygoni Multiflori after processing.

Methods: Various kinds of chromatographic methods were used to deparate the chemical constituents from Radix Polygoni Multiflori after processing. Their structures were determined by NMR and MS spectral data.

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[Influence of process methods on contents of chemical component Radix Polygoni Multiflori].

Zhongguo Zhong Yao Za Zhi

March 2005

The Institute of Basic Theory, China Academy of Traditional Chinese Medicine, Beijing 100700, China.

Different methods of processing Radix Polygoni Multiflori and the change of chemical components including emodin, physcion, 2,3,5,4'-stilbene glucoside, and tannin were investigated. The dried roots of polygoni were processed in different ways, such as, steamed with black bean sauce, steamed with water, stewed with black bean sauce, and stewed with black bean sauce at high pressure, for h and 36 h, respectively. The process stewing with black bean sauce was also investigated for 12, 24, 36 h, and 48 h, respectively.

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[Comparison between the developmental history of Chinese medicine and foreign medicine].

Zhonghua Yi Shi Za Zhi

January 2000

The Institute of Basic Theory, China Academy of Traditional Chinese Medicine, Beijing 100700.

Long-term coexistence, and side-by-side development and two medical system in one country, is the realistic and long-term situation in our country. In the development history of these two medical systems, there are close relation between traditional Chinese medicine(TCM) and the development of philosophical thinking, and between western medicine and the development of natural science. TCM pays attention to the development of clinical medicine, and don't have independent basic medicine which are subordinate to clinical medicine, such as anatomy, nor experimental medicine, such as animal experiments.

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[The history of cupping therapy].

Zhonghua Yi Shi Za Zhi

April 1999

The Institute of Basic Theory of TCM, China Academy of TCM, Beijing.

As an important and integral part of non - drug folk therapy on TCM, there were also many other names for cupping therapy, such as "horning", "needlehorn", "sucking method", "fire - cupping", "boiling bamboo cylinder". By textual investigation, considerable clear recognition can be reached on the names, cupping instruments, cupping measure, indications and contradictions in different historical stages. Presently, cupping therapy is combined with other measures, such as drug therapy, acumoxibustions etc.

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