- The study assessed the effects of cyclophosphamide (CPA) on oocyte fertilization and embryo growth in mice, finding that higher CPA doses (≥400 mg/kg) significantly reduced the number of viable oocytes and fertility rates.
- Despite the decrease in the number of metaphase II oocytes and fertilization rates after high CPA doses, embryos that were fertilized grew normally, with development features resembling those of control group embryos.
- One month post-CPA treatment, both the number of retrievable oocytes and their capability to develop into blastocysts were restored to levels comparable to the control group, indicating a recovery of reproductive potential.
This case highlights an extremely rare situation of bilateral tubal pregnancies occurring after a single-embryo transfer in a woman with a history of infertility.
An ultrasound at 5 weeks confirmed pregnancy signs in both fallopian tubes, and surgery revealed ectopic pregnancy, leading to the removal of both tubes.
This case is unique since previous instances of bilateral tubal pregnancies resulted from multiple ovulations or embryo transfers, raising questions about the origins of the embryonic tissue found in both tubes.