2 results match your criteria: "The Howard Hughes Medical Institute and The Jackson Laboratory[Affiliation]"

Glaucoma refers to a heterogeneous group of disorders that involve retinal ganglion cell death, optic nerve damage, and loss of visual field. Glaucoma is a leading cause of vision loss worldwide, affecting an estimated 67 million people. Elevated intraocular pressure is a major risk factor for glaucoma.

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Purpose: Due to the increasing importance of mouse models and mouse genetics in ophthalmic research, we have developed a goniolens for mice.

Methods: The size and basic design parameters of a human goniolens were adapted to the mouse eye.

Results: The goniolens is straightforward to use and allows non-invasive visualization of the structures of the anterior chamber angle, including Schlemm's canal, trabecular meshwork, iris and anterior surface of the peripheral ciliary body.

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