PROTEIN COAGULATION AND ITS REVERSAL : GLOBIN.

1. The globin prepared from hemoglobin by the acid acetone method is denatured globin. 2.

PROTEIN COAGULATION AND ITS REVERSAL : THE IDENTITY OF NORMAL HEMOGLOBIN WITH THE HEMOGLOBIN PREPARED BY THE REVERSAL OF COAGULATION, AS DETERMINED BY SOLUBILITY TESTS.

1. Methemoglobin prepared from coagulated hemoglobin by the reversal of coagulation has the same solubility within 2 per cent as normal methemoglobin. 2.

THE REACTIONS OF CYANIDE WITH GLOBIN HEMOCHROMOGEN.

Cyanide can react with globin hemochromogen in two different ways. In the first reaction cyanide combines with globin hemochromogen without displacing or competing with globin. In the second reaction cyanide displaces globin.

THE EFFECT OF CATHODE RAYS UPON CERTAIN BACTERIA.

1. For the two motile bacilli, B. coli and B.

PROTEIN COAGULATION AND ITS REVERSAL : THE PREPARATION OF INSOLUBLE GLOBIN, SOLUBLE GLOBIN AND HEME.

1. By a procedure involving the use of acid acetone hemoglobin may be rapidly separated into a precipitate of denatured globin and an acetone solution of heme. 2.

THE PREPARATION OF COMPLETELY COAGULATED HEMOGLOBIN.

As a preliminary to the study of the reversal of the coagulation of hemoglobin several methods are described for the preparation of completely denatured and coagulated hemoglobin and the evidence is given that hemoglobin is a typical coagulable protein.

THE RELATION OF FREQUENCY TO THE PHYSIOLOGICAL EFFECTS OF ULTRA-HIGH FREQUENCY CURRENTS.

1. Biological effects of electromagnetic waves emitted by a vacuum tube oscillator have been studied at frequencis ranging from 8,300,000 to 158,000,000 cycles per second (1.9 to 38 meters wave-length).

THE IMMUNOLOGICAL RELATIONSHIPS OF STREPTOCOCCUS VIRIDANS AND CERTAIN OF ITS CHEMICAL FRACTIONS : II. SEROLOGICAL REACTIONS OBTAINED WITH ANTINUCLEOPROTEIN SERA.

1. The immunological behavior of two cell constituents of nonhemolytic streptococci has been studied, (a) One, the so called nucleoprotein, is relatively non-specific and gives rise to an antibody which shows group reactions with nucleoproteins of related species. (b) The other is non-protein by qualitative chemical tests.

THE IMMUNOLOGICAL RELATIONSHIPS OF STREPTOCOCCUS VIRIDANS AND CERTAIN OF ITS CHEMICAL FRACTIONS : I. SEROLOGICAL REACTIONS OBTAINED WITH ANTIBACTERIAL SERA.

1. Agglutination and precipitation by the specific substance of Streptococcus viridans are parallel phenomena. Separate specific substances have been extracted from strains which are distinct by ordinary serological tests.

DIFFERENTIATION OF OXYHEMOGLOBINS BY MEANS OF MUTUAL SOLUBILITY TESTS.

1. The rule of addition of solubilities is applicable to the differentiation of the oxyhemoglobins of not too closely related species. 2.

PROTEOSE INTOXICATIONS AND INJURY OF BODY PROTEIN : III. TOXIC PROTEIN CATABOLISM AND ITS INFLUENCE UPON THE NON-PROTEIN NITROGEN PARTITION OF THE BLOOD.

The acute intoxication following an injection of a toxic proteose is usually associated with a large increase (40 per cent or more) in the non-protein nitrogen of the blood. This increase is found chiefly in the blood urea nitrogen, but the amino and peptide nitrogens also may show small increases. The changes observed in the blood non-protein nitrogen are identical with those which follow the feeding of large amounts of meat (8).

STUDIES OF LUNG VOLUME : II. TUBERCULOUS MEN.

1. The total capacity, middle capacity, and residual air have been determined in 31 adult male patients suffering from tuberculosis of the lungs. 2.

STUDIES OF LUNG VOLUME : III. TUBERCULOUS WOMEN.

The total capacity, middle capacity, and residual air have been determined in twenty adult women suffering from pulmonary tuberculosis. The chest volumes have been determined in each case and the normal lung volumes calculated by means of the ratios worked out in Paper I and applied to thirty-one men in Paper II. The excursions of the diaphragm have been determined by fluoroscopy in all cases.

AN ELECTROCARDIOGRAPHIC STUDY OF THE ANAPHYLACTIC RABBIT.

Electrocardiographic examination of rabbits during the anaphylactic reaction revealed marked and various changes of the heart's activity in twenty-two out of twenty-four animals. Changes occurred in fatal as well as in non-fatal cases, after the vagi were cut as well as when they were intact. Cardiac disturbances are thus a practically constant result of serum anaphylaxis in the rabbit.