1 results match your criteria: "The Graduate School of the General Hospital of PLA[Affiliation]"
[Photochemotherapy with psoralen and ultraviolet A induced apoptosis of NB4 cells and its effects on caspase-8 and caspase-8 protein expressions].
Zhongguo Zhong Xi Yi Jie He Za Zhi
April 2013
The Graduate School of the General Hospital of PLA, Beijing 100853 , China.
Article Synopsis
- The study investigates the effects of psoralen (PSO) combined with ultraviolet A (UVA) on the apoptosis of human leukemia NB4 cells and the associated signaling pathways.
- The research involved treating NB4 cells with varying concentrations of PSO and UVA exposure times, with apoptosis rates measured using flow cytometry and cell structure analyzed via electron microscopy.
- Results indicate that the combination of PSO and UVA increases apoptosis in a dose- and time-dependent manner, particularly with 40 μg/mL PSO and 5 minutes of UVA, and enhances the expression of Caspase-3 and Caspase-8 proteins involved in the apoptosis process.