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In vitro chemosensitivity assays of retinoblastoma cells.

Int J Clin Oncol

February 2004

Biotechnology Research Center, The Graduate School of Teikyo University of Science and Technology, Uenohara, Yamanashi 409-0193, Japan.

The use of chemotherapy in treating retinoblastoma is presently increasing in importance. Because of the rarity of this disease, excellent in vitro chemosensitivity assays are necessary, not only for individualized testing but also for the development of chemotherapy regimens. It is instructive for improving such assays to discuss in vitro chemosensitivitly tests of tumor cells from clinical specimens according to a cell biological perspective.

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