Spectroscopic studies and Non-Linear optical response through C/N replacement and modulation of electron Donor/Acceptor Units on naphthyridine derivatives.

This study explores the nonlinear optical (NLO) and photophysical properties of newly designed naphthyridine derivatives by density functional theory (DFT). The first hyperpolarizability (β), a key indicator of NLO activity, varies significantly depending on the substituent groups. N-substituted compounds (IUB-N series) generally show lower β values, while compounds with electron donor/acceptor groups (IUB-P series) demonstrate a broader range, with IUB-A-02 achieving the highest β value of 16,362 a.

Blockchain Factors in the Design of Smart-Media for E-Healthcare Management.

According to the current situation of deep aging globally, how to provide low-cost and high-quality medical services has become a problem that the whole society needs to consider. To address these challenges, we propose an e-healthcare management system leveraging the integration of the Internet of Things (IoT) and blockchain technologies. Our system aims to provide comprehensive, reliable, and secure one-stop services for patients.

An innovative subdivision collocation algorithm for heat conduction equation with non-uniform thermal diffusivity.

This paper presents a subdivision collocation algorithm for numerically solving the heat conduction equation with non-uniform thermal diffusivity, considering both initial and boundary conditions. The algorithm involves transforming the differential form of the heat conduction equation into a system of equations and discretizing the time variable using the finite difference formula. The numerical solution of the system of heat conduction equations is then obtained.

Enhanced removal of acidic dyes (AB1 and MO) from binary systems using anion exchange membrane BII: kinetic, isotherm, and thermodynamic analyses.

In the current work, the adsorption of acid black 1 (AB1), a hair dye, and methyl orange (MO) on anion exchange membrane BII (AEM-BII) in a binary system was studied experimentally. The effects study for contact time, adsorbent's and adsorbates' concentration, and temperature of aqueous media on the AB1 and MO removal, AEM-BII recovery, and reusability were also investigated. The highest removal was observed at optimum conditions, 150-min contact time and 5 g L of adsorbent for AB1 (91.

Investigation of 3-Phenylcoumarin Derivatives as Potential Multi-target Inhibitors for Human Cholinesterases and Monoamine oxidases: A Computational Approach.

Alzheimer's disease (AD) is the predominant etiology of dementia, impacting a global population of approximately 50 million individuals. In the field of medicinal chemistry, there have been notable advancements in the utilization of monoamine oxidase (MAO) and cholinesterase (ChE) inhibitors for the purpose of addressing the neurotransmitter shortage associated with Alzheimer's disease (AD). A selection of previously synthesized 3-Phenylcoumarin derivatives (5a-m) were selected for examination in the pursuit of potential multi-targeting inhibitors of MAO-A, MAO-B, AChE, and BChE.

Assessing the potential of nano-formulated chlorfenapyr and clothianidin insecticides-treated sugar baits against Anopheles funestus, Anopeles coluzzii and Culex quinquefasciatus mosquitoes.

Mosquitoes serve as vectors for various diseases like malaria, dengue fever, yellow fever, and lymphatic filarial diseases causing significant global health problems, highlighting the importance of vector control. The study was conducted to assess the effectiveness of nanoformulated clothianidin and chlorfenapyr insecticides treated with ATSB in controlling three mosquito strains. The development of a natural thiolated polymer-coated ATSB nano formulation involved incorporating nano-carriers to deliver insecticides.

Comparative genomic studies on the TGF-β superfamily in blue whale.

TGF-β supergene family has a wide range of physiological functions including cell adhesion, motility, proliferation, apoptosis, and differentiation. We systematically analyzed and characterized the TGF-β gene superfamily from the whole blue whale (Balaenoptera musculus) genome, using comparative genomic and evolutionary analysis. We identified 30 TGF-β genes and were split into two subgroups, BMP-like and TGF-like.

Designing of chitosan/gelatin based nanocomposite films integrated with Vachellia nilotica gum carbon dots for smart food packaging applications.

Microbial growth and exposure to UV light is a persistent global concern resulting in food spoilage, therefore, smart packaging is crucial for the availability of safer and quality food. Present work describes fabrication of chitosan (CH) and gelatin (GL) based nanocomposite films by introducing green source, highly fluorescent Vachillia nilotica gum-derived carbon dots (VNG-CDs). The VNG-CDs and incorporated CH/GL nanocomposite films were characterized by UV-Visible, FTIR, XRD, SEM and TGA analysis.

In silico molecular characterization of TGF-β gene family in : genome-wide analysis.

is a living example of evolutionary processes due to its numerous physiological and ecological adaptations. This is the first study to genetically characterize the TGF-β gene family in at the genome-wide level, and a total of 28 TGF-β gene family homologs are identified. Physicochemical characteristics of TGF-β homologs exhibit a basic nature except for BMP1, BMP4, BMP10, BMP15, AMH, INHA, NODAL Modulator and TGFB1.

Adsorption of Eosin B from Wastewater onto the Prepared Porous Anion Exchange Membrane.

This research describes the fabrication of the porous trimethylamine (TMA)-grafted anion exchange membrane (AEM) over a phase inversion process. The synthesis of the generated AEM was verified using Fourier transform infrared (FTIR) spectroscopy. The fabricated porous AEM showed 240% water uptake (W), 1.

Exploring the advection-diffusion equation through the subdivision collocation method: a numerical study.

The current research presents a novel technique for numerically solving the one-dimensional advection-diffusion equation. This approach utilizes subdivision scheme based collocation method to interpolate the space dimension along with the finite difference method for the time derivative. The proposed technique is examined on a variety of problems and the obtained results are presented both quantitatively in tables and visually in figures.

Emerging trends of carbon emissions and foreign direct investment: accounting for ecological footprints, renewable energy, globalization, and technological innovations in BRICS.

This paper investigates the intricate interplay between carbon emissions and foreign direct investment within the context of Brazil, Russia, India, China, and South Africa (BRICS) for the period spanning 2000 to 2022. In our comprehensive analysis, we incorporate ecological footprint, renewable energy, globalization, and technological innovations as exogenous variables. Employing a system of simultaneous equations across the BRICS panel, we aim to fully elucidate the proposed relationships.

Resistance Modulation of Individual and Polymicrobial Culture of and through Nanoparticle-Coupled Antibiotics.

Polymicrobial mastitis is now becoming very common in dairy animals, resulting in exaggerated resistance to multiple antibiotics. The current study was executed to find drug responses in individual and mixed Culture of and isolated from milk samples, as well as to evaluate the antibacterial potential of tungsten oxide nanoparticles. These isolates (alone and in mixed culture) were further processed for their responses to antibiotics using the disc diffusion method.

Predicting Thalassemia Using Feature Selection Techniques: A Comparative Analysis.

Thalassemia represents one of the most common genetic disorders worldwide, characterized by defects in hemoglobin synthesis. The affected individuals suffer from malfunctioning of one or more of the four globin genes, leading to chronic hemolytic anemia, an imbalance in the hemoglobin chain ratio, iron overload, and ineffective erythropoiesis. Despite the challenges posed by this condition, recent years have witnessed significant advancements in diagnosis, therapy, and transfusion support, significantly improving the prognosis for thalassemia patients.

In Silico Analysis: Genome-Wide Identification, Characterization and Evolutionary Adaptations of Bone Morphogenetic Protein (BMP) Gene Family in Homo sapiens.

We systematically analyzed BMP gene family in H. sapiens to elucidate genetic structure, phylogenetic relationships, adaptive evolution and tissue-specific expression pattern. Total of 13 BMPs genes were identified in the H.

Efficiency of nitrogen, gibberellic acid and potassium on canola production under sub-tropical regions of Pakistan.

The global demand for crop production is rapidly growing due to the continued rise in world population. Crop productivity varies generally with soil nutrient profile and climate. The optimal use of fertilizers might help to attain higher crop yield in canola.

Morpho-anatomical determinants of yield potential in Olea europaea L. cultivars belonging to diversified origin grown in semi-arid environments.

Plant performance is mainly estimated based on plant architecture, leaf features and internal microstructural changes. Olive (Olea europaea L.) is a drought tolerant, oil yielding, and medium sized woody tree that shows specific structural and functional modifications under changing environment.

Accumulation and human health risk assessment of trace elements in two fish species, Cirrhinus mrigala and Oreochromis niloticus, at Tarukri Drain, District Rahimyar Khan, Punjab, Pakistan.

The toxic discharge of heavy metals into the water affects the aquatic ecosystem as well as the human population interacting with it because of their toxicity, bioaccumulation, long persistence, and transfer through the food chain. Thus, it is very important to conduct studies to determine the level of heavy metal pollution in order to better control, manage, and preserve the pollution of aquatic ecosystems. This study assessed heavy metal contamination in fish and its associated health risk to the population around the Tarukri Drain, Punjab, Pakistan.

Application of QPPO/PVA based commercial anion exchange membrane as an outstanding adsorbent for the removal of Eosin-B dye from wastewaters.

Commercially available QPPO/PVA based anion exchange membrane (AEM) BIII was to inquire the percentage discharge of anionic dye Eosin-B (EB) at terrain temperature from wastewater. The impact of EB initial concentration, membrane dosage, ionic strength, contact time and temperature on EB percentage removal was contemplated. The EB percentage removal was increased from 22 to 99.

4-Phthalimidobenzenesulfonamide Derivatives as Acetylcholinesterase and Butyrylcholinesterase Inhibitors: DFTs, 3D-QSAR, ADMET, and Molecular Dynamics Simulation.

Introduction: Alzheimer's disease is a form of dementia which affects majority of the people. It is characterized by memory loss and other cognitive function disabilities and is one of the most challenging neurodegenerative disorders to treat because of its progressive nature. The disease affects millions of people all around the world, and the number of those affected is expanding every day.

Efficient photocatalytic degradation of Rhodamine B dye using solar light-driven La-Mn co-doped FeO nanoparticles.

This work aims to develop a highly efficient solar light-induced photocatalyst based on La-Mn co-doped FeO nanoparticles. Pure FeO and La-Mn co-doped FeO nanoparticles were fabricated by a simple co-precipitation method. The photocatalysts were analyzed for their morphological, structural, and magnetic characteristics.

Adsorption of Methyl Orange from an Aqueous Solution onto a BPPO-Based Anion Exchange Membrane.

In this research, the development of a novel brominated poly(2,6-dimethyl-1,4-phenylene oxide) (BPPO)-based homogeneous anion exchange membrane (AEM) via the solution casting method was reported. Fourier transform infrared spectroscopy was used to confirm the successful development of the BPPO-based AEM. The prepared AEM showed excellent thermal stability.