254 results match your criteria: "The Gertner Institute for Epidemiology and Health Policy Research[Affiliation]"

A comparison between lipid-based vs. glycemic-based insulin sensitivity indices for the association with abnormal ECG findings and 20-year mortality among older adults.

Cardiovasc Diabetol

December 2024

Department of Epidemiology and Preventive Medicine, School of Public Health, Faculty of Health Sciences and Medicine, Tel Aviv University, Tel Aviv, Israel.

Background: A direct comparison between glycemic-based and lipid-based insulin sensitivity indices (ISIs) for ECG findings and all-cause and cardiovascular mortality is lacking.

Methods: 963 community-dwelling older adults, examined as part of the third phase of the Glucose intolerance, Obesity, and Hypertension study between 1999 and 2008, were followed until December 2016 and December 2019 for cardiovascular and all-cause mortality, respectively. Eleven different ISIs were calculated and evaluated against ECG findings, all-cause, and cardiovascular mortality with multivariable regression models.

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Characteristics and survival of hospitalized combat casualties during two major conflicts between Israel and Hamas: 2023 versus 2014.

BMC Emerg Med

December 2024

The Israel National Center for Trauma and Emergency Medicine Research, Gertner Institute for Epidemiology and Health Policy Research, Chaim Sheba Medical Center, Tel-Hashomer, Ramat Gan, Israel.

Background: In the complex landscape of modern warfare, understanding combat-related injuries leading to hospitalization is crucial for optimizing injury treatment. This study aims to compare combat casualty characteristics and outcomes during the major conflicts between Israel and Hamas in 2023 and 2014 as a basis for understanding the effectiveness of trauma care practices for wounded soldiers.

Methods: A cohort study of soldiers hospitalized due to combat injuries during two major wars between Israel and Hamas in 2023 and 2014, using data from the Israeli National Trauma Registry.

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The Swords of Iron (SOI) War is an armed conflict between Israel and Hamas, which has been taking place in Gaza from October 2023 until the present time of writing this article. This war is characterized by urban close contact combat. The combat equipment, weaponry, and protective measures employed, differ markedly from those in previously documented major conflicts, significantly impacting the types of injuries sustained by soldiers.

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Adolescent Blood Pressure and Early Age Stroke.

NEJM Evid

December 2024

The Gertner Institute for Epidemiology and Health Policy Research, Sheba Medical Center, Ramat Gan, Israel.

Background: Underdiagnosis of relevant risk factors has contributed to the increasing stroke incidence in young adults. Blood pressure cut-off values for adolescents are neither sex specific nor based on cardiovascular outcomes.

Methods: This nationwide, population-based, retrospective cohort study included all Israeli adolescents 16-19 years of age who were medically evaluated before compulsory military service from 1985 to 2013, including routine blood pressure measurements.

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Association between the number of individuals injured in a traumatic event and posttraumatic stress disorder among hospitalized trauma patients.

J Trauma Stress

October 2024

Israel Defense Forces Medical Corps, Surgeon General's Headquarters, Israel Defense Forces, Ramat Gan, Israel.

Posttraumatic stress disorder (PTSD) often occurs following mass casualty events, yet the connection between the number of individuals injured in an event and PTSD risk in smaller-scale events (i.e., involving one or several injured persons) remains unclear.

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Article Synopsis
  • Regenerative endodontic treatment offers a promising method for healing damaged tooth structures and supporting root development, but the changes in tooth morphology over time are not well understood.
  • A study monitored 58 patients over five years, revealing a 100% survival rate and a 94.4% success rate, with most cases showing signs of vital tissue and significant changes in root structure within the first 20 months.
  • The findings indicate that the presence of a calcific bridge is a good sign of treatment success and that understanding the timeline of root maturation can help improve patient follow-up and care strategies.
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Background: Ensuring appropriate computed tomography (CT) utilization optimizes patient care while minimizing radiation exposure. Decision support tools show promise for standardizing appropriateness.

Objectives: In the current study, we aimed to assess CT appropriateness rates using the European Society of Radiology (ESR) iGuide criteria across seven European countries.

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'Quantifying the long-term effects of measles infection': author's response.

Clin Microbiol Infect

September 2024

The Bio-statistical and Bio-mathematical Unit, The Gertner Institute for Epidemiology and Health Policy Research, Tel Hashomer, Israel; Department of Epidemiology and Preventive Medicine, School of Public Health, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

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Self-reported physical activity properties and 20-year all-cause and cardiovascular mortality among community-dwelling older adults.

Postgrad Med J

September 2024

Public Health Research Center, The Gertner Institute for Epidemiology and Health Policy Research, Sheba Medical Center, Ramat Gan 52621, Israel.

Purpose: Physical activity was previously associated with decreased mortality. Current guidelines recommend >150 min/week or >75 min/week of moderate or high-intensity exercise to maintain a healthy lifestyle; however, exercise properties most strongly associated with low mortality among the elderly may still be explored.

Methods: A total of 1210 community-dwelling older adults, from the third phase (1999-2004) of the Israel Study on Glucose Intolerance, Obesity, and Hypertension, were followed until 2016 and 2019 for cardiovascular and all-cause mortality, respectively.

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Evaluating the clinical utility of cervical cultures in postpartum endometritis management.

Arch Gynecol Obstet

October 2024

Clinical Microbiology, The Faculty of Medicine and Medical Sciences, Sheba Medical Center, Tel-Aviv University, Tel Aviv-Yafo, Israel.

Purpose: To evaluate the utility of cervical cultures in the diagnosis and management of postpartum endometritis.

Methods: A retrospective study was conducted on 1069 cervical cultures collected from postpartum women with suspected endometritis between 2011 and 2021. Patient demographics, obstetric history, clinical parameters, and culture results were analyzed.

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Despite progress in therapy, heart failure (HF) inflicts a heavy burden of hospital admissions. In this study, we identified among 1360 community-dwelling HF patients (mean age 70.7 ± 11.

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Korean dramas (K-dramas), with their unique characteristics, often encourage binge-watching. Moreover, the cultural norms and rituals surrounding alcohol, prevalent in South Korea, are mirrored in K-dramas that have gained global audiences in recent years. The present study aimed to examine problematic K-drama series watching, and the potential associations with alcohol consumption among global adult audiences from Israel and Indonesia.

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Identification of severely injured children at very low risk of emergent surgery: A national trauma registry study.

Injury

September 2024

Emergency Department, Schneider Children's Medical Center of Israel, Petah Tikva, Israel; Major Trauma Service, The Alfred Hospital, Melbourne, Australia; Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Objective: The number of pediatric trauma patients requiring surgical interventions has been steadily decreasing allowing for a judicious approach to immediately available resources. This study aimed to derive and validate a prediction rule that reliably identifies injured children who are at very low risk for requiring emergency surgery upon emergency department (ED) arrival.

Methods: A retrospective cohort study of data included in the Israeli National Trauma Registry from January 1, 2011, through December 31, 2020, was conducted.

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The association between frailty biomarkers and 20-year all-cause and cardiovascular mortality among community-dwelling older adults.

Postgrad Med

August 2024

Public Health Research Center, the Gertner Institute for Epidemiology and Health Policy Research, Sheba Medical Center, Ramat Gan, Israel.

Objectives: While several biomarkers were previously associated with frailty and mortality, data are still contradicting. We aimed to evaluate the association between novel biomarkers and frailty among community-dwelling older adults to enhance understanding of the pathophysiology of frailty.

Methods: Nine hundred and sixty-three older adults were screened during the third phase (1999-2008) of the Israel study on Glucose Intolerance, Obesity, and Hypertension (GOH).

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An easy-to-use and reliable tool is essential for gait assessment of people with gait pathologies. This study aimed to assess the reliability and validity of the OneStep smartphone application compared to the C-Mill-VR+ treadmill (Motek, Nederlands), among patients undergoing rehabilitation for unilateral lower extremity disability. Spatiotemporal gait parameters were extracted from the treadmill and from two smartphones, one on each leg.

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Objective: Impaired fasting glucose is a prediabetic condition defined as glucose levels of 100-125 mg/dL and is considered a risk factor for type 2 diabetes. However, this definition does not confer to pregnancy. The significance of first-trimester fasting glucose and future progression to diabetes is not well defined.

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A historical cohort study on predictors for successful weaning from prolonged mechanical ventilation and up to 3-year survival follow-up in a rehabilitation center.

Respir Med

June 2024

Department of Epidemiology and Preventive Medicine, School of Public Health, Faculty for Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel; Center for Research of Public Health, The Gertner Institute for Epidemiology and Health Policy Research, Sheba Medical Center, Ramat Gan, Israel; Research and Development Institute, Reuth Tel-Aviv Rehabilitation Medical Center, Tel Aviv, Israel. Electronic address:

Background: We followed prolonged mechanically ventilated (PMV) patients for weaning attempts and explored factors associated with successful weaning and long-term survival.

Methods: This historical cohort study included all adult PMV patients admitted to a single rehabilitation hospital during 2015-2018 and followed for survival according to weaning success up to 3 years or the end of 2021.

Results: The study included 223 PMV patients.

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Exploring pre-MRI imaging tests: patient survey reveals potential implications for healthcare efficiency in Israel.

Isr J Health Policy Res

April 2024

The Gertner Institute for Epidemiology and Health Policy Research, Sheba Medical Center, Tel Hashomer, 5266202, Ramat-Gan, Israel.

Background: Medical imaging tests are vital in healthcare but can be costly, impacting national health expenditures. Magnetic resonance imaging (MRI) is a crucial diagnostic tool for assessing medical conditions. However, the rising demand for MRI scans has frequently strained available resources.

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Emulated Trial for Discharge Prescription of Guideline-Directed Medical Therapy and 15-Year Survival After Coronary Artery Bypass Graft Surgery.

Mayo Clin Proc

May 2024

Research Center for Public Health, The Gertner Institute for Epidemiology and Health Policy Research, Sheba Medical Center, Ramat Gan, Israel; Department of Epidemiology and Preventive Medicine, Faculty of Medicine, School of Public Health, Tel Aviv University, Tel Aviv, Israel. Electronic address:

Objectives: To explore admission and discharge prescription rates of guideline-directed medical therapy (GDMT), defined as aggregate antiplatelet agents, statins, and β-blockers, after coronary artery bypass graft (CABG) surgery and to reveal its association with long-term survival.

Patients And Methods: This is a prospective cohort study-based emulated trial of patients undergoing elective or semi-elective isolated CABG surgery in 7 cardiothoracic units in Israel from January 1, 2004, to December 31, 2007, and followed up until December 31, 2020, for all-cause mortality.

Results: Only 59.

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Hemorrhagic Shock in Isolated and Non-Isolated Pelvic Fractures: A Registries-Based Study.

Prehosp Emerg Care

May 2024

Israel Defense Forces Medical Corps, Surgeon's General Headquarters, Ramat Gan, Israel.

Background: Pelvic fractures resulting from high-energy trauma can frequently present with life-threatening hemodynamic instability that is associated with high mortality rates. The role of pelvic exsanguination in causing hemorrhagic shock is unclear, as associated injuries frequently accompany pelvic fractures. This study aims to compare the incidence of hemorrhagic shock and in-hospital outcomes in patients with isolated and non-isolated pelvic fractures.

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Injury as a Result of Children and Adolescent Labor-An Association with Ethnicity and Peripherality: A Retrospective Cohort Study Based on the Israeli Trauma Registry.

Eur J Investig Health Psychol Educ

December 2023

Department of Emergency and Disaster Management, School of Public Health, Faculty of Medicine, Tel Aviv University, Tel Aviv 6139001, Israel.

Background: Working children and adolescents face a heightened risk of work-related injuries. This research aimed to assess the rate of hospitalizations resulting from work-related injuries among children and adolescents in Israel, with a specific focus on disadvantaged populations.

Methods: This nationwide retrospective cohort study utilized The Israeli National Trauma Registry (INTR).

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Public health-focused use of COVID-19 rapid antigen and PCR tests.

Sci Rep

January 2024

The Gertner Institute for Epidemiology and Health Policy Research, Sheba Medical Center, Ramat Gan, Israel.

During the Covid-19 pandemic, accurate PCR tests were augmented by the cheap, rapid, and logistically convenient, yet less sensitive antigen tests. In Israel, a testing policy shift was implemented due to limited availability of PCR tests during the Omicron surge. Thus, both PCR and antigen tests were used, as this was the only alternative for mass testing and surveillance at the time.

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Perceived functional resilience in schools according to key stakeholders.

Sci Rep

January 2024

Department of Emergency and Disaster Management, School of Public Health, Sackler Faculty of Medicine, Tel Aviv University, P.O. Box 39040, 6139001, Tel Aviv, Israel.

Amid the COVID-19 outbreak, Israel and numerous other governments closed schools as a precaution, leading to a sudden shift to online learning. The aim of the current study is to provide foundational insight into the perceived readiness of the school system to withstand future adversities, based on the challenges, complexities, as well as successes in adaptation faced by stakeholders during COVID-19. In this cross-sectional study, we assess the perceived levels of functional resilience of the school system among the key stakeholders of the Israeli education system-high school students, parents, teachers, and principals, as well as a composite functional resilience scale.

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The association of medical, social, and normative factors with the implementation of end-of-life care practices.

Isr J Health Policy Res

January 2024

Department of Emergency and Disaster Management, School of Public Health, Faculty of Medicine, Tel-Aviv University, PO Box 39040, 6997801, Tel-Aviv-Yafo, Israel.

Background: End-of-life (EoL) care practices (EoLCP) are procedures carried out at the EoL and bear directly on this stage in the patient's life. Public support of these practices in Israel is far from uniform. Previous studies show that while ∼30% of participants support artificial respiration or feeding of terminally ill patients, 66% support analgesic treatment, even at the risk of shortening life.

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Introduction: Seasonality in the incidence of stroke has been examined in numerous studies, yet data on whether it differs with age are limited. To fill this gap, we utilized a largescale dataset from Israel.

Patients And Methods: We retrieved data of all hospitalizations for ischemic stroke (IS), transient ischemic attack (TIA) and intra cerebral hemorrhage (ICH) from 2000 to 2020.

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