9 results match your criteria: "The Fourth Medical Center of the General Hospital of the People's Liberation Army[Affiliation]"
Evaluation of the therapeutic effects of nebulized inhalation of hydrogen-rich water on primary blast lung injury in C57BL/6 mice.
Surgery
January 2025
Senior Department of Burns & Plastic Surgery, Institute of Burn in the Fourth Medical Centre, Chinese PLA General Hospital, Beijing, China. Electronic address:
Background: Primary blast lung injury is a common and severe consequence of explosion events, characterized by immediate and delayed effects such as apnea and rapid shallow breathing. The overpressure generated by blasts leads to alveolar and capillary damage, resulting in ventilation-perfusion mismatch and increased intrapulmonary shunting. This reduces the effective gas exchange area, causing hypoxemia and hypercapnia.
View Article and Find Full Text PDFA plain language summary of results from the TORCHLIGHT trial of toripalimab plus chemotherapy for metastatic or recurrent triple-negative breast cancer.
Future Oncol
December 2024
TopAlliance Biosciences, Rockville, MD, USA.
Clinical characteristics and booster vaccine effectiveness of the Omicron variant.
BMC Infect Dis
November 2024
Beijing Chest Hospital, Capital Medical University, Beijing, 101149, China.
Article Synopsis
- The study analyzed the characteristics and outcomes of COVID-19 patients during a Beijing Omicron outbreak, focusing on the impact of vaccination status on clinical severity and survival rates.
- Data was collected from 1495 cases, showing that vaccination, especially booster shots, significantly reduced disease severity and increased survival time compared to non-vaccinated individuals.
- Results indicated that elderly patients with pre-existing health conditions had a higher risk of severe illness and death, highlighting the importance of vaccination in this vulnerable population.
Guidelines and consensus: Jejunoileostomy for diabetes mellitus-surgical norms and expert consensus (2023 version).
World J Diabetes
November 2024
Department of General Surgery, The Third Medical Center of the General Hospital of the People's Liberation Army, Beijing 100039, China.
Article Synopsis
- Diabetes mellitus (DM) is a condition marked by high blood sugar levels due to inadequate insulin production, requiring patients to undergo long-term treatment with existing hypoglycemic drugs, which are often ineffective for managing the disease.
- Traditional weight loss surgeries, like gastric bypass, have strict BMI requirements and can lead to complications such as hypoglycemia and dumping syndrome, reducing their effectiveness for DM treatment.
- Jejunoileostomy is a newer surgical option showing promise for improving glucose and lipid metabolism without altering the gastrointestinal structure, resulting in fewer complications and better management of DM-related issues, supported by clinical consensus on its surgical and postoperative management.
Diagnosis and treatment of anterior cruciate ligament injuries: Consensus of Chinese experts part II: Graft selection and clinical outcome evaluation.
J Orthop Translat
September 2024
Inner Mongolia Autonomous Region People's Hospital, Hohhot, Inner Mongolia Autonomous Region, China.
Article Synopsis
- There has been significant progress in diagnosing and treating ACL injuries in China, with ACL reconstruction widely recognized for restoring knee stability, though standardized protocols are still needed.
- The Chinese Association of Orthopaedic Surgeons and the Chinese Society of Sports Medicine collaborated to create an expert consensus aimed at improving diagnostic and treatment standards for ACL injuries.
- Experts focused on "Graft Selection" and "Clinical Outcome Evaluation" during the consensus development, concluding that while there is no definitive graft choice, each option has its benefits and drawbacks regarding healing, availability, costs, and risks, particularly for young athletes.
Performance Improvement and Application of Degradable Poly-l-lactide and Yttrium-Doped Zinc Oxide Hybrid Films for Energy Harvesting.
ACS Appl Mater Interfaces
July 2024
State Key Laboratory of Solidification Processing, School of Materials Science and Engineering, Northwestern Polytechnical University, Xi'an 710072, P. R. China.
Piezoelectric nanogenerators (PENGs) are booming for energy collection and wearable energy supply as one of the next generations of green energy-harvesting devices. Balancing the output, safety, degradation, and cost is the key to solving the bottleneck of PENG application. In this regard, yttrium (Y)-doped zinc oxide (ZnO) (Y-ZnO) was synthesized and embedded into polylactide (PLLA) for developing degradable piezoelectric composite films with an enhanced energy-harvesting performance.
View Article and Find Full Text PDFA life-threatening, massive subcutaneous hematoma caused by trauma in a patient with neurofibromatosis type 1: a case report and literature review.
Front Oncol
May 2024
Burns and Plastic Surgery Department, The Fourth Medical Center of the General Hospital of the People's Liberation Army, Beijing, China.
Background: Neurofibromatosis type 1 (NF1) is an autosomal dominant disease that can give rise to the formation of vascular lesions in affected individuals. These lesions, whether occurring spontaneously or as a result of trauma, have the potential to cause severe and even fatal hemorrhage.
Case Description: We presented a case demonstrating the most extensive hematoma ever documented in a patient with NF1, resulting from a minor trauma.
Regression-based Chinese norms of number connection test A and digit symbol test for diagnosing minimal hepatic encephalopathy.
Sci Rep
February 2024
Institute of Liver Disease, Beijing University of Chinese Medicine, Beijing, China.
Number connection test A (NCT-A) and digit symbol test (DST), the preferential neuropsychological tests to detect minimal hepatic encephalopathy (MHE) in China, haven't been standardized in Chinese population. We aimed to establish the norms based on a multi-center cross-sectional study and to detect MHE in cirrhotic patients. NCT-A and DST were administered to 648 healthy controls and 1665 cirrhotic patients.
View Article and Find Full Text PDFToripalimab plus nab-paclitaxel in metastatic or recurrent triple-negative breast cancer: a randomized phase 3 trial.
Nat Med
January 2024
TopAlliance Biosciences, Rockville, MD, USA.
Article Synopsis
- The TORCHLIGHT trial tested the combination of the immune-checkpoint inhibitor toripalimab and nab-paclitaxel (nab-P) against a placebo with nab-P in patients with advanced triple-negative breast cancer (TNBC).
- Results showed that the toripalimab group had a significantly longer progression-free survival (PFS) of 8.4 months compared to 5.6 months for the placebo group, particularly in PD-L1-positive patients.
- The overall survival was also better for the toripalimab group (32.8 months vs. 19.5 months), and the safety profile was similar between groups, suggesting that toripalimab is a promising treatment for this cancer type.