LINC00994 promoted invasion and proliferation of gastric cancer cell via regulating miR-765-3p.

Emerging studies indicated that lncRNA is one crucial regulator in development and tumorigenesis. We firstly showed that LINC00994 was overexpressed in GC cells compare with GES-1. Compared to adjacent samples, the LINC00994 expression was increased in GC tissues by qRT-PCR assay.

Long noncoding RNA MALAT1 promotes uveal melanoma cell growth and invasion by silencing of miR-140.

Increasing evidences have demonstrated that long noncoding RNAs (LncRNAs) play a significant role in the development of tumor. However, the role of metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) in uveal melanoma remains unknown. In this study, we demonstrated that the expression of MALAT1 was upregulated in the uveal melanoma tissues compared to normal tissues.

Luteolin improves the impaired nerve functions in diabetic neuropathy: behavioral and biochemical evidences.

Peripheral neuropathies are a major cause of morbidity in patients with diabetes mellitus. Up to now, drugs for improving the impaired nerve functions has been lacking for diabetic neuropathy. The antioxidant and neuroprotective effects of luteolin make it an attractive candidate for diabetic neuropathy.

CD192 gene variant and susceptibility to cervical cancer: a meta analysis.

Background: Several molecular epidemiological studies have explored the association between G46295A variant of CD192 gene and cervical cancer susceptibility in distinct populations. However, the results are contradictory. To provide convincing evidence for the association, we performed the present meta-analysis incorporating all case-control studies.

MicroRNA-543 acts as an oncogene by targeting PAQR3 in hepatocellular carcinoma.

MicroRNAs (miRNAs) are small, non-coding RNAs that can act as oncogenes or tumor suppressor genes in human cancer. Increasing evidences indicate that deregulation of miRNAs contributes to the hepatocarcinogenesis. In this study, we demonstrated that the levels of miR-543 were dramatically increased in clinical hepatocellular carcinoma (HCC) tissues and cell lines.