Retrospective study of outcomes in hyalgan®-treated patients with osteoarthritis of the knee.

Objective: To evaluate therapeutic success [defined as lack of total knee replacement surgery (TKR) or other significant clinical intervention during a 6-month follow-up] and to identify baseline patient and disease characteristics associated with improved pain relief and quality of life (QOL) in patients in a clinical practice who were treated with a single course of Hyalgan® (intra-articular hyaluronan) for pain associated with osteoarthritis (OA) of the knee.

Design And Setting: This was an uncontrolled, retrospective study conducted at a single US clinical orthopaedic practice.

Patients: 248 patients with moderate to severe OA of the knee.