2 results match your criteria: "The First People Hospital of Xiaoshan[Affiliation]"

Escin activates AKT-Nrf2 signaling to protect retinal pigment epithelium cells from oxidative stress.

Biochem Biophys Res Commun

December 2015

Eye Center, The 2nd Affiliated Hospital, Medical College of Zhejiang University, Hangzhou, China; Zhejiang Provincial Key Lab of Ophthalmology, Hangzhou, China. Electronic address:

Here we explored the anti-oxidative and cytoprotective potentials of escin, a natural triterpene-saponin, against hydrogen peroxide (H2O2) in retinal pigment epithelium (RPE) cells. We showed that escin remarkably attenuated H2O2-induced death and apoptosis of established (ARPE-19) and primary murine RPE cells. Meanwhile, ROS production and lipid peroxidation by H2O2 were remarkably inhibited by escin.

View Article and Find Full Text PDF

Objective: To evaluate the therapeutic effects of three different intervertebral fusion with bone graft and internal fixation in the treatment of cervical spondylotic myelopathy.

Methods: In the retrospective study, 83 patients (38 males and 45 females, with an average age of 69 years) with cervical spondylotic myelopathy were divided into three groups. The patients in three groups were treated by autogenous iliac bone grafting (Robingson grafting) with anterior cervical plate-screw fixation, Pyramesh with anterior cervical plate-screw fixation and BAK fixation respectively.

View Article and Find Full Text PDF