5 results match your criteria: "The First People's Hospital of Shaoguan City[Affiliation]"
Long non-coding RNA Gm37494 alleviates osteoarthritis chondrocyte injury via the microRNA-181a-5p/GABRA1 axis.
J Orthop Surg Res
June 2022
Department of Joint and Sports Medicine, The First People's Hospital of Shaoguan City, No.3 Dongdi South Road, Zhenjiang District, Shaoguan, 512000, Guangdong, People's Republic of China.
Objective: This study was conducted to investigate the effect of long non-coding RNA (lncRNA) Gm37494 on osteoarthritis (OA) and its related molecular mechanism.
Methods: The cartilage tissues were obtained from OA patients, and an OA mouse model was induced by the destabilization of the medial meniscus, followed by measurement of Gm37494, microRNA (miR)-181a-5p, GABRA1 mRNA, and the encoded GABAR protein expression. Thereafter, a cellular model was induced by interleukin-1β (IL-1β) treatment in chondrocytes, followed by ectopic and silencing experiments.
Overexpression of miR-146a Might Regulate Polarization Transitions of BV-2 Cells Induced by High Glucose and Glucose Fluctuations.
Front Endocrinol (Lausanne)
October 2019
Department of Neurology, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, China.
Microglia are critical in neuroinflammation. M1/M2 polarization transitions of microglial phenotypes determine the states of neuroinflammation and are regulated by multiple pathways, including miRNAs and other epigenetic regulations. This study investigated the polarization transitions of microglia induced by high glucose and glucose fluctuations, and the role of miR-146a in regulating M1/M2 polarization transitions of microglia.
View Article and Find Full Text PDFUnusual coexistence of extramedullary plasmacytoma and nasopharyngeal carcinoma in nasopharynx.
Diagn Pathol
September 2015
Department of Pathology, The First Affiliated Hospital, Sun Yat-sen university, 58, Zhongshan Road II, Guangzhou, 510080, China.
Nasopharyngeal carcinoma (NPC) is an EBV-associated malignant tumor of nasopharynx. As extremely rare condition, the second primary cancer of nasopharynx can occur in NPC patients synchronously or subsequently. Extramedullary plasmacytoma (EMP) is a rare tumor and commonly originates in the head and neck region.
View Article and Find Full Text PDF[Risk factors and predictive factors of cognitive deterioration in patients of vascular cognitive impairment no dementia with subcortical ischemic vascular disease].
Zhonghua Yi Xue Za Zhi
February 2014
Department of Neurology II, the First People's Hospital of Shaoguan City, Shaoguan 512000, China.
Objective: To explore the independent risk factors and predictive factors of cognitive deterioration in patients of vascular cognitive impairment no dementia with subcortical ischemic vascular disease (VCIND-SIVD).
Methods: The clinical and neuropsychological characteristics of 96 VCIND-SIVD patients were collected and their cognitive states re-assessed after one year. The distribution of continuous and categorical variables was examined with univariate analysis.
[Application of autogenous artery to repair parotid duct defect].
Shanghai Kou Qiang Yi Xue
August 2013
Department of Oral and Maxillofacial Surgery, the First People's Hospital of Shaoguan City, Guangdong Medical College. Shaoguan 512000, Guangdong Province,
Purpose: To use autogenous artery to repair parotid duct defect, and to investigate the clinical effect.
Methods: Anesthesia epidural catheter was used to support the parotid duct and a segment of superficial temporal artery was harvested to reconstruct the defect of the parotid duct. The patients were asked to revisit 1 month, 3 months, half a year and one year postoperatively.