1 results match your criteria: "The First Hospital of Qiqihar City. Qiqihar 161000[Affiliation]"
[Inhibiting effect and mechanism of Lactobacillus E6-1 on oral cancer cell line Cal-27].
Shanghai Kou Qiang Yi Xue
December 2019
Department of Oral and Maxillofacial Surgery, The First Hospital of Qiqihar City. Qiqihar 161000, Heilongjiang Province,China.
Article Synopsis
- The study aimed to evaluate the effects of Lactobacillus E6-1 on the growth and apoptosis of the human oral cancer cell line Cal-27.
- The MTT assay indicated that Lactobacillus E6-1 inhibited cell proliferation in a dose-dependent manner, while agarose gel electrophoresis revealed DNA fragmentation indicative of apoptosis.
- Additionally, Western blot analysis showed increased expression levels of cyt-c, caspase-9, and caspase-3, suggesting that Lactobacillus E6-1 effectively induces apoptosis in Cal-27 cells.