415 results match your criteria: "The First Hospital of Qinhuangdao[Affiliation]"
BMC Med
December 2024
National Clinical Research Center for Cardiovascular Diseases, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 167, Beilishi Rd, Beijing, 100037, Xicheng District, China.
Background: Low-density lipoprotein cholesterol (LDL-C) is a well-recognized risk factor for cardiovascular diseases. However, several clinical studies demonstrated an inverse association between LDL-C and mortality risk in patients with acute myocardial infarction (AMI), known as the lipid paradox. This study aims to investigate the potential impact of inflammation on the association between LDL-C levels and mortality risks.
View Article and Find Full Text PDFInvest Ophthalmol Vis Sci
December 2024
School of Control Engineering, Northeastern University at Qinhuangdao, Qinhuangdao, China.
Purpose: The purpose of this study was to quantitatively evaluate the branching patterns and vascular fragmentation features in preclinical and early diabetic retinopathy (DR) using optical coherence tomography angiography (OCTA).
Methods: OCTA metrics, including branch node number (BNN), branch node density (BND), end point number (EPN), end point density (EPD), fragmented vessel segment count (FVSC), and fragmented vascular length ratio (FVLR), were measured in foveal and parafoveal regions within superficial and deep vascular plexus (SVP and DVP) in the retina.
Results: Compared to healthy control (HCs), both BNN and BND exhibited a significant decrease in individuals with mild DR across both retinal layers, and also in diabetes mellitus without DR (no DR) within DVP.
Clin Radiol
November 2024
Department of Radiology, The First Hospital of Qinhuangdao, China.
Aim: To develop a larynx preservation (LP) score model to predict laryngectomy-free survival (LFS) in advanced laryngeal squamous-cell carcinoma (LSCC) with morphological response to neoadjuvant chemotherapy (NAC).
Materials And Methods: In this retrospective study, patients with advanced LSCC were included. All patients were classified into NAC response and non-response groups according RECIST.
Sci Rep
December 2024
Department of Internal Medicine, Hebei Medical University, Shijiazhuang, 050017, Hebei Province, China.
Previous studies have reported an association between telomere length and non-alcoholic fatty liver disease (NAFLD). This study aimed to explore the involvement of alternative lengthening of telomere-related genes (ALTRGs) in the pathology of NAFLD, construct a risk signature, and evaluate both treatment and prognosis. Three NAFLD datasets (GSE48452, GSE89632, and GSE63067) were collected from the GEO database and merged into combined GEO datasets.
View Article and Find Full Text PDFPak J Med Sci
December 2024
Jie Gong Department of Critical Care Medicine People's Hospital of Yangjiang, Yangjiang 529599, Guangdong, China.
Sci Rep
November 2024
Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences, No. 167 Beilishi Road, Xicheng District, Beijing, 100037, China.
Although serum uric acid (SUA) is a risk factor for cardiometabolic outcome, but it remains unclear which patients with coronary artery disease (CAD) benefit the most from SUA lowering therapy (ULT). The association of SUA level, systemic inflammation and cardiometabolic risk is still unclear. The current study is aimed to examine whether SUA-associated cardiometabolic risk is modulated by systemic inflammation in CAD patients.
View Article and Find Full Text PDFJ Imaging Inform Med
November 2024
Department of Radiology, The First Hospital of Qinhuangdao, Qinhuangdao, 066000, Hebei, China.
Heliyon
November 2024
Department of Cardiology, National Clinical Research Center for Cardiovascular Diseases, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Background: The optimal glycosylated hemoglobin (HbA1c) target in type 2 diabetes mellitus (T2DM) patients remains controversial, especially in patients with concomitant coronary heart disease (CHD). This study aimed to investigate the correlation between baseline HbA1c and long-term prognosis in CHD patients with T2DM.
Methods: The study enrolled 6,839 CHD patients with T2DM and measured HbA1c at admission in a multicenter prospective observational cohort.
Appl Biochem Biotechnol
November 2024
Department of Otolaryngology, the Second Hospital of Hebei Medical University, No. 215 Heping West Road, Shijiazhuang, 050000, Hebei, China.
The incidence of laryngeal squamous cell carcinoma (LSCC) has been rising recently. LSCC is one of the most prevalent malignant tumors of the head and neck. In this study, we aimed to investigate whether tripartite motif containing 71 (TRIM71) could serve as a molecular target for the treatment of LSCC.
View Article and Find Full Text PDFClin Biomech (Bristol)
January 2025
Department of Orthopedics, The First Hospital of Qinhuangdao, Qinhuangdao, China. Electronic address:
Background: All-inside cruciate ligament reconstruction is an emerging technique for treating anterior cruciate ligament and posterior cruciate ligament injuries. The all-inside technique uses a 4-stranded graft made of a single tendon that wraps around itself. Four strands of the graft must be immobilized to form a closed loop, and the free ends of the graft must be attached using a suture technique.
View Article and Find Full Text PDFRadiologie (Heidelb)
November 2024
Department of Medical Imaging, The First Hospital of Qinhuangdao, Qinhuangdao, China.
Endocr J
November 2024
Department of Pulmonary and Critical Care Medicine, The First Hospital of Qinhuangdao, Qinhuangdao 066000, Hebei, China.
The correlation of obesity and metabolic abnormalities with asthma and non-alcoholic hepatic steatosis has been extensively studied. However, the association between asthma and non-alcoholic hepatic steatosis has been largely overlooked. This study aims to investigate the potential association between asthma risk and the fatty liver index (FLI), a validated indicator of non-alcoholic fatty liver disease (NAFLD).
View Article and Find Full Text PDFDiabetes Metab Syndr Obes
November 2024
Department of Endocrinology, The First Hospital of Qinhuangdao, Qinhuangdao, Hebei, People's Republic of China.
Purpose: To investigate the relationship between obesity indices and sarcopenia in postmenopausal patients with type 2 diabetes mellitus (T2DM) at different body mass index (BMI) levels.
Patients And Methods: This retrospective cross-sectional study included 298 hospitalized postmenopausal women diagnosed with T2DM. We collected demographic, biochemical, and anthropometric data on each subject.
Acta Radiol
November 2024
Department of Radiotherapy, The First Hospital of Qinhuangdao City, Qinhuangdao, Hebei Province, PR China.
Background: Concurrent chemoradiotherapy (CCRT) is used as the primary treatment modality for currently limited cervical cancer and lacks non-invasive quantitative parameters to assess clinical outcomes of treatment for cervical cancer treatment.
Purpose: To develop nomograms based on clinical prognostic factors and apparent diffusion coefficient (ADC) in predicting downstaging and progression-free survival (PFS) after CCRT for cervical cancer.
Material And Methods: X-tile was used to calculate the optimal threshold for ΔADC(%) for prognostic stratification.
Brain Res
January 2025
Department of Anesthesiology, The Second Hospital of Hebei Medical University, Shijiazhuang 050000, China; Hebei Key Laboratory of Neurodegenerative Disease Mechanism, Shijiazhuang 050000, China; Key Laboratory of Clinical Neurology (Hebei Medical University), Ministry of Education, Shijiazhuang 050000, China. Electronic address:
Esketamine is commonly used for sedation or general anaesthesia in infants and young children. However, repeated esketamine administration during periods of rapid brain growth and development may result in various pathophysiological and cognitive changes. Therefore, this study aimed to investigate the influence of recurrent esketamine exposure on long-term behavioural and white matter consequences.
View Article and Find Full Text PDFBMC Med Inform Decis Mak
November 2024
Department of Geriatric Orthopedics, Third Hospital of Hebei Medical University, Shijiazhuang, Hebei, 050051, China.
Mol Neurobiol
November 2024
Department of Neurology, The Second Hospital of Hebei Medical University, Shijiazhuang, 050000, Hebei, China.
J Orthop Surg Res
October 2024
Department of Orthopedics, The First Hospital of Qinhuangdao, Qinhuangdao, China.
Purpose: The aim of this study was to characterize the biomechanical properties of a novel side-to-side tenorrhaphy (SST), this tenorrhaphy is designed to achieve reliable strength utilizing fewer knots and greater operationalization. This is compared with a well-established tendon reconstruction technique called the Pulvertaft weave technique (PWT).
Methods: Twenty fresh porcine hindfoot flexor tendons were collected, and 10 novel SST and 10 PWT were performed in each group.
Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
September 2024
Department of Critical Care Medicine, the Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, Hebei, China. Corresponding author: Zuo Zhigang, Email:
Medicine (Baltimore)
September 2024
Orthopedics Department, The First Hospital of Qinhuangdao, Qinhuangdao, Hebei, China.
To investigate the treatment outcomes of combined internal and external fixation surgery for patients with posterior lateral tibial plateau fractures and explore its safety. The study was conducted from February 2020 to February 2023 and included a total of 77 patients with Schatzker IV and Schatzker V type posterior lateral tibial plateau fractures. Patients were divided into control group and treatment group according to different treatment methods: the control group with 38 cases received treatment with dual-support plates, and the study group with 39 cases received treatment with internal fixation using medial plates combined with lateral locking plates.
View Article and Find Full Text PDFJ Cancer Res Ther
August 2024
Department of Gynecology, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Introduction: Accumulating evidence suggests the significant involvement of GADD45G in the development of various cancers. This study investigates GADD45G's involvement and methylation status in endometrial cancer (EC), along with molecular mechanisms and potential therapies.
Methods: The expression of GADD45G in EC tissues and controls was evaluated using RNA-seq, quantitative real-time polymerase chain reaction (qRT-PCR), and western blotting (WB).
Sci Rep
August 2024
The First Hospital of Qinhuangdao, No.258 Wenhua Road, Qinhuangdao, 066000, Hebei Province, People's Republic of China.
Dysmobility Syndrome (DMS), is a combination, that is analogous to the approach taken with metabolic syndrome, The diagnosis of DMS is complex. So this study aimed to explore the relationship between 25-(OH) Vit D with Dysmobility Syndrome (DMS)in type 2 diabetes mellitus(T2DM) patients. This is a cross-sectional study, including 330 patients (67.
View Article and Find Full Text PDFFront Surg
August 2024
Department of Vascular Surgery, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Int J Ophthalmol
August 2024
Department of Ophthalmology, the First Hospital of Qinhuangdao, Qinhuangdao 066000, Hebei Province, China.
Aim: To analyze the distribution of fibrovascular proliferative membranes (FVPMs) in proliferative diabetic retinopathy (PDR) patients that treated with pars plana vitrectomy (PPV), and to evaluate the outcomes separately.
Methods: This was a retrospective and cross-sectional study. Consecutive 25-gauge (25-G) PPV cases operated for PDR from May 2018 to April 2020.
BMC Infect Dis
August 2024
Department of Cardiology, The First Hospital of QinHuangDao, Qinhuangdao, Hebei, 066000, China.