1 results match your criteria: "The First Hospital of Ningbo City 59 Liuting St.[Affiliation]"
Upregulation of miR-137 protects anesthesia-induced hippocampal neurodegeneration.
Int J Clin Exp Pathol
June 2015
Department of Anesthesia, The First Hospital of Ningbo City 59 Liuting St., Ningbo 315010, Zhejiang, China.
Purpose: Ketamine is commonly used in pediatric anesthesia but may cause neurodegeneration in young brains. The aim of the study is to use an animal model to characterize the role of microRNA 137 (miR-137) in ketamine-induced neurodegeneration in neonatal hippocampus.
Methods: Young Sprague-Dawley Rats (1 month old) was systemically administrated with ketamine (75 mg/kg) for 3 days.