2 results match your criteria: "The First Hospital Affiliated to the Xinxiang Medical University[Affiliation]"
Down-regulation of Rab17 promotes tumourigenic properties of hepatocellular carcinoma cells via Erk pathway.
Int J Clin Exp Pathol
April 2016
Department of Intervention, The First Hospital Affiliated to The Xinxiang Medical University Xinxiang, Henan, China.
The small GTPase, Ras-related protein 17 (Rab17), a member of the Rab family, plays a critical role in the regulation of membrane traffic in polarized eukaryotic cells. However, the role of Rab17 in hepatocellular carcinoma (HCC) is not clear. Clinical speciments reveal that Rab17 was present in 15 of 20 (75.
View Article and Find Full Text PDFThe microRNA-367 inhibits the invasion and metastasis of gastric cancer by directly repressing Rab23.
Genet Test Mol Biomarkers
February 2015
1 Department of General Surgery, The First Hospital Affiliated to the Xinxiang Medical University, Xinxiang, Henan, China .
Article Synopsis
- Dysregulated microRNAs are linked to gastric cancer, affecting processes like cell cycle, apoptosis, and invasion, with a focus on the role of miR-367.
- The study analyzed the expression of miR-367 in 37 gastric cancer patients and its impact on cancer cell lines, revealing a significant reduction of miR-367 in cancer tissues and its correlation with tumor characteristics.
- Overexpression of miR-367 decreased cell migration and invasion, identifying Rab23 as its target gene, suggesting that miR-367 could be a promising therapeutic agent for gastric cancer.