The significance of combined detection of CysC, urinary mAlb and β-MG in diagnosis of the early renal injury in pregnancy-induced hypertension syndrome.

Objective: To elaborate the significance of combined detection of cystatin C, urinary micro-albumin (mAlb) and β-microglobulin (β-MG) in diagnosis of the early renal injury in pregnancy-induced hypertension syndrome.

Methods: A total of 120 patients with pregnancy-induced hypertension syndrome who were admitted to this hospital for treatment between November 2015 and October 2018 were enrolled as subjects, and divided into the control group (without complication of renal injury, n = 76) and the observation group (with complication of renal injury, n = 44) according to the complications of early renal injury. Furthermore, 60 patients who participated in the antenatal care in this hospital were enrolled as the normal subjects (normal group).

Preparation, spectroscopy and molecular modelling studies of the inclusion complex of cordycepin with cyclodextrins.

The inclusion complexes of cordycepin with cyclodextrins (CDs) were prepared, the resultant complexes were characterised by UV-vis, FTIR, DSC, SEM, XRD, ESI-MS and proton nuclear magnetic resonance spectroscopy ((1)H NMR). The stoichiometry was established using a Job plot and the inclusion mechanism was clarified using molecular dynamic simulations. Molecular modelling calculations have been carried out to rationalise the experimental findings and predict the stable molecular structure of the inclusion complex.