8 results match your criteria: "The First Clinical Medical College of Guangdong Medical University[Affiliation]"
Encapsulated papillary carcinoma of breast: Comparative study of multimodal ultrasound manifestations and pathological features.
Clin Hemorheol Microcirc
December 2024
Department of Ultrasonography, the Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
Article Synopsis
- The study aimed to analyze conventional and contrast-enhanced ultrasound (CEUS) characteristics of encapsulated papillary carcinoma (EPC) in breast cancer patients and assess the diagnostic value of CEUS.
- The research involved a retrospective review of 16 patients with confirmed EPC, highlighting that the disease is more common in postmenopausal women and typically appears as complex cystic and solid masses on ultrasound.
- Findings indicated that CEUS provides additional clarity on the solid components of EPC, aiding in diagnosis and preoperative procedures, emphasizing the importance of combining CEUS with clinical assessments for more accurate diagnosis.
The influence of task-irrelevant color perception on flanker task performance: Insights from behavioral and ERP data.
Physiol Behav
October 2024
Department of Orthopedic, The 92962 Military Hospital of CPLA, Guangzhou, Guangdong, 510000, China.
Perception of color as a task-relevant stimulus can affect cognition and behavior in the flanker task; however, it remains unclear whether it has the same impact when it is a task-irrelevant stimulus dimension. To this end, we applied four-letter flanker tasks with or without colored (red/blue) to 23 healthy young adults, while recording the event-related potentials (ERPs) and behavioral performance. The flanker task included four kinds of color types: non-color letter (NC), all color letter (AC), flanker color letter (FC), and target color letter (TC), each flanker task included congruent and incongruent conditions.
View Article and Find Full Text PDFTislelizumab plus neoadjuvant chemotherapy and concurrent chemoradiotherapy versus neoadjuvant chemotherapy and concurrent chemoradiotherapy for locally advanced nasopharyngeal carcinoma: A retrospective study.
Transl Oncol
October 2024
Specialty of Head and Neck Oncology of Affiliated Hospital Guangdong Medical University, Zhanjiang 524001, PR China. Electronic address:
Article Synopsis
- The study retrospectively analyzed the effectiveness of combining tislelizumab with neoadjuvant chemotherapy and concurrent chemoradiotherapy (CCRT) for treating locally advanced nasopharyngeal carcinoma (LA-NPC).
- Results showed that patients receiving due to tislelizumab demonstrated significantly higher response rates, including complete response and progression-free survival (PFS), compared to those who only received standard treatment.
- The conclusion highlights that tislelizumab, when paired with neoadjuvant chemotherapy and CCRT, offers promising therapeutic benefits and tolerability for LA-NPC patients compared to traditional methods.
Long Non-Coding RNA B3GALT5-AS1 Suppresses Keloid Progression by Regulating the β-Trcp1-Mediated Ubiquitination of HuR.
Clin Cosmet Investig Dermatol
April 2024
Department of Burn Surgery, Huizhou Municipal Central Hospital, Huizhou, 516001, People's Republic of China.
Background: lncRNA β‑1,3‑galactosyltransferase 5‑AS1 (B3GALT5-AS1) plays a vital regulatory role in colon and gastric cancers. However, the biological functions and regulatory mechanisms of B3GALT5-AS1 in keloid progression remain unknown. This study aims to investigate the molecular mechanisms in the B3GALT5-AS1-regulated keloid proliferation and invasion.
View Article and Find Full Text PDF[Experimental Study on the Mechanism of Mangiferin Inhibiting Malignant Biological Characteristics of Multiple Myeloma and Exerting Anticancer Effect].
Zhongguo Shi Yan Xue Ye Xue Za Zhi
June 2023
Department of Hematology, The First Clinical Medical College of Guangdong Medical University, Dongguan Key Laboratory of Environmental Medicine, Dongguan 523808, Guangdong Province, China,E-mail:
Objective: To investigate the effect of pure Chinese herbal extract Mangiferin on the malignant biological behaviors of multiple myeloma (MM) cells, and to analyze the molecular mechanism of the anti-myeloma effect of Mangiferin, so as to provide experimental basis for MM replacement therapy.
Methods: U266 and RPMI8226 of human MM cell lines were intervened with different concentrations of Mangiferin. Cell proliferation was detected by CCK-8 method.
[The Effects and Regulatory Mechanism of Targeting CXC Chemokine Receptor 1/2 Combined with Ara-C on the Malignant Biological Behaviors of U937 Cells of Acute Myeloid Leukemia].
Zhongguo Shi Yan Xue Ye Xue Za Zhi
April 2023
Department of Hematology, The First Clinical Medical College of Guangdong Medical University, Dongguan Key Laboratory of Environmental Medicine, Dongguan 523808, Guangdong Province, China,E-mail:
Article Synopsis
- The study aims to assess how a CXCR1/2 targeting inhibitor, Reparixin, combined with the chemotherapy drug cytarabine (Ara-C), affects acute myeloid leukemia (AML) cells, specifically looking at tumor behavior and CXCR family expression.
- Researchers used various methods to analyze cell shape, growth, invasion, and death in AML cells treated with Reparixin and Ara-C, comparing results to treatments with each drug alone.
- Results showed that the combination therapy significantly reduced cancer cell growth and spread while increasing cell death and autophagy, indicating potential for improved AML treatment strategies.
LINC00460 Promotes Cutaneous Squamous Cell Carcinoma Progression Through Stabilizing ELAVL1 Protein.
Mol Biotechnol
August 2023
Department of Burn Surgery, The First Clinical Medical College of Guangdong Medical University, Huizhou, 516001, China.
Long intergenic noncoding ribonucleic acid (lncRNA) 460 is reportedly associated with carcinogenesis and progression in various types of cancer. However, the mechanisms underlying its action in cutaneous squamous cell carcinoma (CSCC) remain unclear. LINC00460 mRNA expression was analysed using data from the Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) databases.
View Article and Find Full Text PDFIdentification and validation of transferrin receptor protein 1 for predicting prognosis and immune infiltration in lower grade glioma.
Front Mol Neurosci
November 2022
Department of Pathology, The First Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong, China.
Introduction: Transferrin receptor protein 1 (TFRC), an ananda molecule associated with ferroptosis, has been identified as affecting a wide spectrum of pathological processes in various cancers, but the prognostic value correlates with the tumor microenvironment of TFRC in lower-grade glioma (LGG) is still unclear.
Materials And Methods: Clinical pathological information and gene expression data of patients with LGG come from The Cancer Genome Atlas (TCGA), Chinese Glioma Genome Atlas (CGGA), GTEx, Oncomine, UCSC Xena, and GEO databases. We then used various bioinformatics methods and mathematical models to analyze those data, aiming to investigate the clinical significance of TFRC in LGG and illustrate its association with tumor immunity.