3 results match your criteria: "The First Affiliation Hospital of China Medical University[Affiliation]"

To evaluate the predictive utility of N6-methyladenosine (m6A)-associated long non-coding RNAs (lncRNAs) for the prognosis and immunotherapy response in papillary renal cell carcinoma (pRCC). Transcriptomic data of pRCC samples were extracted from the TCGA database. The m6A-related lncRNAs were identified by Pearson correlation analysis.

View Article and Find Full Text PDF
Article Synopsis
  • The study investigates the genetic links between chronic rhinosinusitis (CRS) and various autoimmune diseases to clarify their association, which is not well understood.
  • Researchers utilized methods like Mendelian randomization and transcriptome-wide association to analyze data from several genetic databases.
  • Results indicate significant associations, showing that CRS is genetically correlated with autoimmune conditions like allergic rhinitis, asthma, rheumatoid arthritis, hypothyroidism, and type 1 diabetes.
View Article and Find Full Text PDF

Background: Second-generation androgen receptor inhibitors (ARIs) have been developed and approved for treating castration-resistant prostate cancer (CRPC). There is a lack of direct comparison of the therapeutic effects and adverse events between the conventional ARI (bicalutamide) and three second-generation ARIs (enzalutamide, apalutamide and darolutamide).

Methods: Our network meta-analysis evaluated therapeutic effects and adverse events of the conventional ARI (bicalutamide) and the second-generation ARIs in treating CRPC.

View Article and Find Full Text PDF