6 results match your criteria: "The First Affiliated of Soochow University[Affiliation]"
Topological features of brain functional networks are reorganized during chronic tinnitus: A graph-theoretical study.
Eur J Neurosci
January 2025
Department of Ear, Nose, and Throat, The First Affiliated of Soochow University, Suzhou, China.
This study aimed to investigate the topological properties of brain functional networks in patients with tinnitus of varying durations. A total of 51 tinnitus patients (divided into recent-onset tinnitus (ROT) and persistent tinnitus (PT) groups) and 27 healthy controls (HC) were recruited. All participants underwent resting-state functional MRI and audiological assessments.
View Article and Find Full Text PDFEffect of Ipsilateral, Contralateral or Bilateral Repetitive Transcranial Magnetic Stimulation in Patients with Lateralized Tinnitus: A Placebo-Controlled Randomized Study.
Brain Sci
June 2022
Department of Ear, Nose, and Throat, Shaanxi Provincial People's Hospital, Xi'an 710068, China.
The relative benefit of ipsilateral, contralateral, and bilateral repetitive transcranial magnetic stimulation (rTMS) for tinnitus treatment remains unclear, especially for patients with lateralized tinnitus. In this study, we compared outcomes after 10 sessions of 1-Hz rTMS at 110% of resting motor threshold over a two-week period. In total, 104 right-handed patients with lateralized subjective tinnitus were randomly divided into four groups according to rTMS treatment: Left (n = 29), Right (n = 23), Bilateral (n = 30), and Sham stimulation (n = 22).
View Article and Find Full Text PDFThe role of LGR5 and ALDH1A1 in non-small cell lung cancer: Cancer progression and prognosis.
Biochem Biophys Res Commun
June 2015
Affiliated Suzhou Hospital of Nanjing Medical University, 26 Daoqian Road, Suzhou 215000, Jiangsu, PR China. Electronic address:
The Leucine rich repeat containing G protein coupled receptor 5 (LGR5), may be a candidate marker of non-small cell lung cancer (NSCLC) cells with stem cell-like properties. Aldehyde dehydrogenase 1A1 (ALDH1A1) is one of NSCLC stem cell markers. To identify the relationship of LGR5 and ALDH1A1 in NSCLC, we analyzed the expression of LGR5 and ALDH1A1 in NSCLC samples, and determined their clinical significance.
View Article and Find Full Text PDFOverexpression of B7-H3 in CD133+ colorectal cancer cells is associated with cancer progression and survival in human patients.
J Surg Res
May 2014
Department of Immunology, School of Basic Medical Sciences, Soochow University, Suzhou, People's Republic of China; Institute of Clinical Immunology of Jiangsu Province, The First Affiliated of Soochow University, Suzhou, People's Republic of China; Stem cell Research Laboratory of Jiangsu Province, Soochow University, Suzhou, People's Republic of China. Electronic address:
Article Synopsis
- Cancer stem-like cells in colorectal cancer are often marked by CD133, but its specific role is still unclear.
- B7-H3, a molecule that helps tumors evade immune response, is found in a significant portion of colorectal cancer samples and can indicate tumor severity when co-expressed with CD133.
- Patients showing both B7-H3 and CD133 expressions tend to have worse survival rates and more severe tumor characteristics, highlighting their potential as important biomarkers for cancer progression.
Efficacy and safety of adjunctive cilostazol to dual antiplatelet therapy after stent implantation: an updated meta-analysis of randomized controlled trials.
J Cardiovasc Pharmacol Ther
May 2013
Clinical Pharmacology Research Laboratory, The First Affiliated of Soochow University, Suzhou, China.
Background: Aspirin and clopidogrel dual antiplatelet therapy (DAT) reduce ischemic events in patients with cardiovascular disease. However, recurrent ischemic event occurrence during DAT remains a major concern. This systematic review assesses the efficacy and safety of adjunctive cilostazol to DAT in combination with DAT on reducing clinical adverse events.
View Article and Find Full Text PDFMutation-sensitive molecular switch method to detect CES1A2 mutation in the Chinese Han and Yao populations.
Genet Test Mol Biomarkers
September 2011
Clinical Pharmacology Research Laboratory, The First Affiliated of Soochow University, Suzhou, China.
Carboxylesterase 1 (CES1) is involved in the metabolic activation of a variety of prodrugs into active derivatives and plays an important role in pharmacokinetics and pharmacodynamics. A single-nucleotide polymorphism, A(-816)C, of the CES1A2 gene has been shown to enhance transcription efficiency and increase enzyme activity. The aim of this study was to develop an easy method to detect this polymorphism.
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