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Modified Volumetric Modulated Arc Therapy in Left Sided Breast Cancer After Radical Mastectomy With Flattening Filter Free Versus Flattened Beams.
Medicine (Baltimore)
April 2016
From the Department of Radiation Oncology, The First Affiliated Hospital of Xiamen University (YL, SW, LS, LF, HH, QL), and Xiagang Community Health Service Centers, The First Affiliated Hospital of Xiamen University (YC), Xiamen, PR China.
Article Synopsis
- Conventional volumetric modulated arc therapy (C-VMAT) for breast cancer has limitations by exposing larger areas of normal tissue to low radiation doses after radical mastectomy.
- A study involving 20 patients tested three types of VMAT plans (C-VMAT, modified-VMAT, and modified-VMAT with flattening filter-free beams) alongside 3D conformal radiotherapy to assess the impact on dose distribution and efficiency.
- Results showed that while C-VMAT was better than 3DCRT in medium to high doses, the modified plans (M-VMAT and M-VMAT-F) reduced low-dose areas and provided better protection for surrounding organs, with M-VMAT-F slightly outperforming M