2 results match your criteria: "The First Affiliated Hospital of Ningbo University (Ningbo First Hospital)[Affiliation]"

Genetically identification of endometriosis and cancers risk in women through a two-sample Mendelian randomization study.

Sci Rep

April 2024

Department of Urology, Ningbo Medical Center Lihuili Hospital, Ningbo University, Ningbo, 315000, Zhejiang, People's Republic of China.

Endometriosis is a prevalent and chronic inflammatory gynecologic disorder affecting approximately 6-10% of women globally, and has been associated with an increased risk of cancer. Nevertheless, previous studies have been hindered by methodological limitations that compromise the validity and robustness of their findings. In this study we conducted a comprehensive two-sample Mendelian randomization analysis to explore the genetically driven causal relationship between endometriosis and the risk of cancer.

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Identification of novel protein biomarkers from the blood and urine for the early diagnosis of bladder cancer via proximity extension analysis.

J Transl Med

March 2024

Department of Urology, Key Laboratory of Translational Research for Urology of Ningbo City, Key Laboratory of Precision Medicine for Atherosclerotic Diseases of Zhejiang Province, The First Affiliated Hospital of Ningbo University (Ningbo First Hospital), Ningbo, Zhejiang, China.

Background: Bladder cancer (BC) is a very common urinary tract malignancy that has a high incidence and lethality. In this study, we identified BC biomarkers and described a new noninvasive detection method using serum and urine samples for the early detection of BC.

Methods: Serum and urine samples were retrospectively collected from patients with BC (n = 99) and healthy controls (HC) (n = 50), and the expression levels of 92 inflammation-related proteins were examined via the proximity extension analysis (PEA) technique.

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