4 results match your criteria: "The First Affiliated Hospital of Nanjing Medical University China. Electronic address: doctorlvqiang@njmu.edu.cn.[Affiliation]"
CircFAM64A(3) promoted bladder cancer proliferation and inhibited CD8 + T cell via sponging to miR-149-5p and activated IL-6/JAK/STAT pathway.
Int Immunopharmacol
January 2025
Department of Urology, The First Affiliated Hospital of Nanjing Medical University China. Electronic address:
Background: The significance of circular RNA in tumour biology is increasingly recognized. This study aims to explore the value of circFAM64A(3) in the proliferation and immune evasion of bladder cancer.
Methods: Bioinformatics were used to identify the differentially expressed circular RNAs in bladder cancer.
Hsa_circ_0003098 promotes bladder cancer progression via miR-377-5p/ACAT2 axis.
Genomics
September 2023
Department of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 21000, Jiangsu Province, PR China. Electronic address:
Accumulating evidence has proven that circRNAs play vital roles in tumor progression. Nevertheless, the mechanisms underlying circRNAs in bladder cancer (BCa) remain largely unknown. The purpose of this study was to identify the role and investigate the potential molecular mechanisms of hsa_circ_0003098 in BCa.
View Article and Find Full Text PDFQuantitative multiparametric MRI as a promising tool for the assessment of early response to neoadjuvant chemotherapy in bladder cancer.
Eur J Radiol
December 2022
Department of Radiology, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Gulou District, Nanjing 210029, PR China. Electronic address:
Article Synopsis
- MRI is being evaluated as a tool to predict how well bladder cancer patients respond to neoadjuvant chemotherapy (NAC), specifically targeting those with muscle-invasive bladder cancer (MIBC).
- A study involving 24 patients showed that certain MRI parameters can effectively predict NAC response, particularly the apparent diffusion coefficient (ADC) values measured at different times.
- The newly developed quantitative RECIST (qRECIST) model demonstrated high accuracy and predictive ability for identifying patients who are likely to benefit from NAC treatment.
Exosomes in urological diseases - Biological functions and clinical applications.
Cancer Lett
September 2022
Department of Urology, The First Affiliated Hospital of Nanjing Medical University (Jiangsu Province Hospital), Nanjing, 210029, PR China. Electronic address:
Exosomes are extracellular vesicles with a variety of biological functions that exist in various biological body fluids and exert their functions through proteins, nucleic acids, lipids, and metabolites. Recent discoveries have revealed the functional and biomarker roles of miRNAs in urological diseases, including benign diseases and malignancies. Exosomes have several uses in the diagnosis, treatment, and monitoring of urological diseases, especially cancer.
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