VASN promotes colorectal cancer progression by activating the YAP/TAZ and AKT signaling pathways via YAP.

Colorectal cancer (CRC) is one of the most common gastrointestinal malignancies. Vasorin (VASN) has been reported to be critical in tumor development and angiogenesis. However, VASN has not been reported in CRC, and its role is unclear.

[Influencing factors of the occurrence of propagated sensation effects at Zusanli (ST 36) based on artificial intelligence technology].

Objective: To explore the influencing factors of the occurrence of propagated sensation effects at Zusanli (ST 36) based on artificial intelligence technology.

Methods: A total of 272 undergraduates and postgraduates of Guangzhou University of TCM were recruited. The basic information, including TCM constitution, body weight index (BMI), pulse, tongue and coating, face complexion, as well as the occurrence of propagated sensation effects at Zusanli (ST 36) with different acupuncture needles and techniques, were recorded.

Effects of Educational Counseling as Solitary Therapy for Chronic Primary Tinnitus and Related Problems.

The aim of this study was to evaluate the early and sustained effects of tinnitus educational counseling on chronic primary tinnitus and related problems. A descriptive longitudinal cohort study was conducted with 159 adult patients suffering from chronic primary tinnitus and sleep problems. All patients received tinnitus educational counseling, sleep adjustment, and vegan dietary advice.

[Effects of electroacupuncture anesthesia of different frequencies on stress reaction in thyroid surgery].

Objective: To probe into the optimal frequency of electroacupuncture for the access to the best anesthesia.

Methods: Sixty cases of optional thyroid surgery were randomly divided into group A, group B and group C, 20 cases in each group. In group A, 2 Hz/100 Hz disperse-dense wave was selected in stimulation.

[Randomized controlled study on acupuncture treatment for chronic fatigue syndrome].

Objective: To observe the therapeutic effect of acpuncture treatment for chronic fatigue syndrome (CFS).

Methods: Nighty cases of CFS were randomly divided into an observation group and a control group, 45 cases in each group. The observation group was treated with acupunture at Renying (ST 9), Fengfu (GV 16), Baihui (GV 20); the control group was treated with 250 mL 5% Glucose injectio combined with 20 mL Shenmai injectio.

[Effect of catgut implantation at acupoint on gonadal hormone and beta-endorphin in patients of climacteric syndrome].

Objective: To explore the clinical therapeutic effect of catgut implantation at acupoint on climacteric syndrome (CS) and its mechanism.

Methods: Sixty cases were randomly divided into a catgut implantation group and a western medicine group, 30 cases in each group. The catgut implantation group was treated by catgut implantation at Shenshu (BL 23), Zigong (EX-CA 1), Sanyinjiao (SP 6).

[Observation on therapeutic effect of acupoint application on dysmenorrhea of excess syndrome and effect on prostaglandins].

Objective: To observe therapeutic effect of acupoint application on dysmenorrhea of excess syndrome and its effect on prostaglandins.

Methods: The patients with primary dysmenorrhea of excess syndrome were randomly divided into an application group and a medication group. The application group of 31 cases were treated with application of Chinese medicine composed of Zhinanxing (Rhizoma Arisaematis), Sanleng (Rhizoma Sparganii), Ezhu (Rhizoma Zedoariae), etc.

[Effects of volatile oil of Rhizoma Acori Tatarinowii on morphology and cell viability in cultured cardiac myocytes].

Objective: To observe the effects of volatile oil of Rhizoma Acori Tatarinowii (VOSCP) on morphology and cell viability in cultured neonate rat cardiac myocytes.

Methods: The cardiac myocytes were cultured by trypsin under cool treatment, and the cell purity was assayed with imminocytochemistry; Morphological changes were observed under phase contrast microscope after cardiac myocytes with VOSCP of different concentration for 24h in vitro, and the cell viability was examed by MTT assay.

Results: The purity of cultured neonate rat cardiac myocytes was higher than 95%; VOSCP of different concentration could depress pulse frequency and 100-160 mg/L VOSCP can obviously improve the viability of cardiac myocytes.

[Effects of acupuncture under guidance of qi street theory on endocrine function in the patient of epilepsy].

Objective: To observe effects of acupuncture under guidance of qi street theory on endocrine function in the patient of epilepsy.

Methods: Sixty cases of epilepsy were randomly divided into an acupuncture-medicine group and a medication group, 30 cases in each group. The medication group were treated with Valpromide, and the acupuncture-medicine group were treated with Valpromide and acupuncture at main points Renying (ST 9), Fengfu (GV 16), Tianzhu (BL 10).

[Effects of beta-asarone on expression of FOS and GAD65 in cortex of epileptic rat induced by penicillin].

Objective: To study effects of beta-asarone on expression of FOS and GAD65 in cortex of epileptic rat induced by penicillin.

Methods: The epileptic animal models were induced by penicillin. The rats were randomly divided into beta-asarone of high (100 mg/kg), medium (50 mg/kg), low (25 mg/kg) dose group, positive control group (Phenytoin sodium), negative control group (matrix).

[Protective effects of beta-asarone on cultured rat cortical neurons damage induced by glutamate].

Objective: To study the protective effects of beta-asarone on cultured rat cortical neurons damage induced by glutamate.

Methods: The protective effects of beta-asarone on cultured rat cortical neurons after glutamate intoxication were observed with morphology, extent of damage, livability, Intracellular calcium concentration and apoptosis ratio.

Results: Morphological changes, LDH leakage and intracellular calcium concentration increasing, cell survival decreasing were observed in cultured rat cortical neurons exposured to glutamate; 7.

[Ultrasonographic study on effects of Wendan Xiezhuo method in improving vascular endothelial diastolic function and atherosclerosis in hypertension patients with turbid-phlegm syndrome].

Objective: To observe the effect of Wendan Xiezhuo method (WXM) on carotid arteriosclerosis and vascular endothelial diastolic function in essential hypertension (EH) patients with turbid-phlegm syndrome (TPS).

Methods: Forty-three EH patients of medium and low risk with TPS were randomly assigned to two groups, the Wendan Tablet (WT) group (23 cases) and the placebo group (20 cases), they were treated with WT and placebo respectively on the base of amlodipine treatment to control the blood pressure. Carotid intimamedia thickness (IMT), atherosclerotic plaque score of carotid artery, endothelium-dependent dilation (EDD) and flow-mediated vasodilation (FMD) of brachial artery after taking nitroglycerin were detected with ultrasonography before and after 6 months of treatment.

[Effects of modified longdan xiegan decoction on hyperandrogenism in patients with polycystic ovary syndrome of stagnant fire in Gan channel type].

Objective: To observe the therapeutic effect of modified Longdan Xiegan Decoction (LXD) on hyperandrogenism in patients with polycystic ovary syndrome (POS) of stagnant fire in Gan channel type.

Methods: Forty-eight patients were divided into two groups: the LXD group (25 cases) treated with LXI) for 3 months, and the Diane-35 group (23 cases) with Diane-35. Condition of menstruation, acne, hairiness were observed, basal body temperature (BBT) was measured, and the serum levels of luteinizing hormone (LH), follicle-stimulating hormone (FSH), prolactin (PRL), free testosterone (FT), and androstenedione (A) were detected before and after 3 months' treatment.

[Effects of shexiang baoxin pill on carotid atheromatous plaque].

Objective: To study the effects of Shexiang Baoxin Pill (SBP) in treating carotid atherosclerosis (CAS).

Methods: Forty-one CAS patients were randomly assigned to 2 groups, the SBP group (31 cases) treated with SBP plus routine treatment and the control group (10 cases) with routine treatment only. Both were treated for 6 months.

[Clinical observation on electroacupuncture for treatment of chronic fatigue syndrome].

Objective: To observe clinical therapeutic effect of acupuncture at Back-shu acupoints of five zang-organs on chronic fatigue syndrome (CFS).

Methods: Forty cases of CFS were treated with electroacupuncture at main acupoints Back-shu, and Fatigue Assessment Instrument (FAI) and Mental State Self-rating Scale (SCL-90) were used for assessment of therapeutic effect.

Results: After electroacupuncture treatment, clinical symptoms improved.

[Advances of clinical studies on acupuncture and moxibustion for treatment of obesity in recent 10 years].

Objective: To Sum up advances of studies on acupuncture for treatment of obesity in recent 10 years and to put forward the problems should be paid attention to and the development direction in clinical scientific research.

Methods: Review the literature about acupuncture and moxibustion slimming therapy in recent 10 years from characteristics of acupuncture and moxibustion in selection of acupoints, analysis of various therapeutic methods, problems in clinical research.

Conclusion: Acupuncture and moxibustion treatment of obesity has obvious therapeutic effect and less side-effects with flexible selection of acupoints and more methods.

Effects of the Chinese drugs for activating blood circulation on plasma TXB2 and 6-keto-PGF1alpha contents in rabbits with glucocorticoid-induced femoral head necrosis.

In the femoral head necrosis model rabbit induced by endotoxin combined with methylprenisolone, the dynamical changes of plasma TXB2 and 6-keto-PGF1alpha contents were observed. As a result, microscopic examination showed that in the model group, bone trabeculae became fine, empty bone lacunae increased, and osteoblasts in number decreased; the ratio of TXB2 and 6-keto-PGF1alpha was out of balance, and these changes worsened gradually with the lapse of time; Compound Sheng Mai Cheng Gu Capsules could reverse femoral head necrosis, protect the vascular endothelial cells, recover the balance of TXB2 and 6-keto-PGF1alpha. It is concluded that the hormone-induced femoral head necrosis is closely related with blood stasis, and that the Chinese drugs for activating blood circulation and removing blood stasis can prevent the femoral head from development of necrosis.