Individual virome analysis reveals the general co-infection of mammal-associated viruses with SARS-related coronaviruses in bats.

Bats are the natural reservoir hosts for SARS-related coronavirus (SARSr-CoV) and other highly pathogenic microorganisms. Therefore, it is conceivable that an individual bat may harbor multiple microbes. However, there is limited knowledge on the overall co-circulation of microorganisms in bats.

Sex Differences and Temporal Trends in Revascularization and Outcomes of ST-Elevation Myocardial Infarction in Older Adults in the United States.

Background: Previous studies have suggested that in-hospital mortality is higher in younger women with ST-segment elevation myocardial infarction (STEMI) than in men. However, more coronary artery disease diagnoses occurred in patients older than 60 years.

Aim Of The Study: This study sought to investigate the temporal trends and sex differences in revascularization and in-hospital outcomes in older STEMI patients.

[The standardization of inflammation detecting methods in upper and lower airways].

To investigate the standardization of inflammation detecting methods in upper and lower airways. After a five year cooperation with Guangzhou Institute of Respiratory Diseases on inflammatory diseases of airways, we have found a series of evaluation methodology and normative values in upper and lower airways (NO), airway hyper reactivity and cytology (Eos). The normative range of nasal and pulmonary NO is 400-900 ppb and 5-25 ppb respectively.

The acute effect of continuous positive airway pressure titration on blood pressure in awake overweight/obese patients with obstructive sleep apnoea.

Objectives: Continuous positive airway pressure (CPAP) improves upper airway obstruction in patients with obstructive sleep apnoea (OSA), who often are overweight-obese. Although it is thought that CPAP improves long-term blood pressure control (BP), the impact of acute and short-term CPAP use on the cardiovascular system in obese patients has not been described in detail.

Methods: Obese patients (body mass index, BMI > 25 kg/m) with OSA were studied awake, supine during incremental CPAP titration (4-20 cmHO, +2 cmHO/3 mins).

The normative value of inflammatory cells in the nasal perfusate of Chinese adults: a pilot study.

Objective: To establish stable, well-accepted nasal perfusion and a normative value of classifying cells in the nasal perfusate of Chinese adults.

Methods: A total of 500 healthy adults were divided into two groups of 250 people per group (group A, 16-30 years old and group B, 31-60 years old; male-to-female ratio, 1:1). All volunteers were non-smokers; they were irrigated with saline, and multiple inflammatory cells in the perfusate were analyzed.

Absence of relationships between tuberculin responses and development of adult asthma with rhinitis and atopy.

Objective: To investigate the relationship between tuberculin skin responses and the development of adult asthma, rhinitis, and atopy.

Methods: Two hundred fourteen patients with mild-to-moderate asthma accompanied with rhinitis and 220 normal volunteers underwent a medical history, chest radiography, allergen skin-prick testing (SPT), bovine Mycobacterium tuberculosis vaccine (BCG) scar identification, purified protein derivative (PPD) tuberculin skin testing, serum-total and serum-specific IgE measurements, and bronchial provocation (provocative dose of histamine causing a 20% fall in FEV(1) [PD(20)]).

Results: Thirty-one normal volunteers (14.