18 results match your criteria: "The First Affiliated Hospital of Dalian Medical University Dalian 116011[Affiliation]"
Am J Cancer Res
May 2024
Department of Urology, The First Affiliated Hospital of Dalian Medical University Dalian 116011, Liaoning, China.
[This corrects the article on p. 3947 in vol. 12, PMID: 36119838.
View Article and Find Full Text PDFZhongguo Zhong Yao Za Zhi
November 2023
Institute (College) of Integrative Medicine, Dalian Medical University Dalian 116044,China.
Circadian rhythm refers to the daily rhythmic variations in an organism. The irregular lifestyles of modern humans have led to a high incidence of chronic diseases, highlighting an inseparable relationship between disrupted circadian rhythm and disease development. TCM has long discussed rhythmic variations, with records dating back to the Yellow Emperor's Inner Canon(Huang Di Nei Jing), which laid a rich theoretical foundation for the research on circadian rhythm.
View Article and Find Full Text PDFPhytomedicine
July 2024
College of Pharmacy, Dalian Medical University, Western 9 Lvshunnan Road, Dalian 116044, China. Electronic address:
Shanghai Kou Qiang Yi Xue
October 2022
Department of Stomatology, The First Affiliated Hospital of Dalian Medical University. Dalian 116011, Liaoning Province, China. E-mail:
Purpose: The effect of different frequencies of Er:YAG laser on bond properties of zirconia ceramic was investigated.
Methods: 3 mm×3 mm ×2 mm Y-TZP blocks were randomly divided into 6 groups(n=5):control group (C),sandblasting group (SB) and Er:YAG laser group (A1-A4) in which the frequencies were 5, 10, 15 and 20 Hz, respectively, IPS e.max Press ceramics were used as group B.
Am J Cancer Res
August 2022
Department of Urology, The First Affiliated Hospital of Dalian Medical University Dalian 116011, Liaoning, China.
Clear cell renal cell carcinoma (ccRCC) accounts for 75% of the total incidence of renal cancer, and every year the number of morbidity and mortality increases, posing a serious threat to public health. The current main treatment methods for kidney cancer include drug-targeted therapy and immunotherapy. Although there are many treatment options for kidney cancer, they all have limitations, including drug resistance, unsatisfied long-term benefits, and adverse effects.
View Article and Find Full Text PDFZhongguo Zhong Yao Za Zhi
May 2022
Anhui University of Chinese Medicine Hefei 230012, China Institute of Traditional Chinese Medicine Resources Protection and Development, Anhui Academy of Chinese Medicine Hefei 230012, China Anhui Province Key Laboratory of Research & Development of Chinese Medicine Hefei 230012, China.
The purpose of this study is to establish a molecular method to identify Xanthii Fructus and two adulterants, the fruits of Xanthium mongolicum and X. italicum. Xanthii Fructus is the fruit of X.
View Article and Find Full Text PDFZhongguo Zhong Yao Za Zhi
August 2020
the First Affiliated Hospital of Dalian Medical University Dalian 116011,China Key Laboratory of Molecular Mechanism for Repair and Remodeling of Orthopaedic Diseases of Liaoning Province Dalian 116011,China.
Osteoporosis fracture with high disability and mortality is a difficult problem that seriously affects the life quality of individuals. At present, there is still a lack of anti-osteoporosis drugs with clear target and significant efficacy in the clinical practice. Rehmanniae Radix and its prescriptions have significant clinical effects.
View Article and Find Full Text PDFAm J Transl Res
February 2020
Department of Orthopedics, The First Affiliated Hospital of Dalian Medical University, Institute (College) of Integrative Medicine, Dalian Medical University Dalian 116011, China.
Fatty acids (FAs) are potential therapeutic agents for cutaneous wound healing; however, the mechanisms underlying this effect have not been clearly defined. In this study, we extracted and characterized FAs from dried larvae and investigated the molecular basis by which FAs promote cutaneous wound healing. We first confirmed that FA sodium salts (FASSs) stimulated proliferation, migration, and tube formation of cultured (HUVECs) in a dose-dependent manner.
View Article and Find Full Text PDFRSC Adv
February 2019
Institute (College) of Integrative Medicine, Dalian Medical University Dalian 116011 China +86-411-83622844 +86-411-83635963.
Numerous studies have revealed that the status of intestinal microbiota has a marked impact on inflammation, which may progressively aggravate the systemic inflammatory response caused by acute pancreatitis (AP). However, our understanding of microbial communities in the intestinal tract is still very limited. Therefore, the aim of this paper is deciphering bacterial community changes in AP rats.
View Article and Find Full Text PDFRSC Adv
June 2018
Regenerative Medicine Center, The First Affiliated Hospital of Dalian Medical University Dalian 116011 China +86-411-83635963-2170.
Accompanied by the increasing demand for organ transplants and personalized medicine, recent years have witnessed great developments in the regeneration of tissues/organs, which has benefited from various manufacturing technologies, especially 3D bioprinting. In 3D bioprinting, according to the morphogenesis, cellular microenvironment, and biological functions of the native tissues/organs, cells and biomaterials are printed by layer-by-layer assembly to form 3D bio-functional units. However, there are still substantial differences between existing 3D printed constructs and actual tissues and organs, especially in microscale structures such as vascular networks.
View Article and Find Full Text PDFInt J Clin Exp Med
February 2016
Department of Pediatrics, The First Affiliated Hospital of Dalian Medical University Dalian 116011, Liaoning Province, PR China.
Purpose: Data about the association between serum uric acid and metabolic syndrome in healthy adolescents are sparse. This study examined this association and determined the optimal cutoffs for serum uric acid to predict metabolic syndrome among healthy adolescents.
Methods: During 2010-2011, we conducted a cross-sectional study of 927 adolescents (53.
Int J Clin Exp Med
January 2016
Department of Neurological, The First Affiliated Hospital of Dalian Medical University Dalian 116011, China.
Objective: To develop psychosocial adaptation scale for Parkinson's disease (PD) in Chinese population and evaluate its reliability and validity.
Methods: The items were designed by literature review, expert consultation and semi-structured interview. The methods of corrected item-total correlation, discrimination analysis and exploratory factor analysis were used for items selection.
Int J Clin Exp Pathol
October 2016
Department of Radiation Oncology, The Second Affiliated Hospital of Dalian Medical University Dalian 116027, China.
Lung cancer is one of the main causes in cancer-related death. Here we reported a novel functional role of Aristaless-like homeobox1 (ALX1) in lung carcinogenesis. Analysis of ALX1 in lung cancer specimens confirms upregulation of ALX1 in lung cancer, especially these with distant metastasis.
View Article and Find Full Text PDFShanghai Kou Qiang Yi Xue
August 2015
Department of Dentistry, The First Affiliated Hospital of Dalian Medical University. Dalian
Purpose: To observe arctigenin's inhibitory effect on oral squamous cell carcinoma, and explore the possible mechanism.
Methods: The expression of VEGF in 32 cases of oral squamous cell cancer and 20 adjacent tissue specimen were detected with immunohistochemistry. Human nude mouse transplantation tumor model of oral squamous cell cancer was prepared with HSC-3 cells line.
Int J Clin Exp Pathol
April 2016
Department of Biochemistry and Molecular Biology, Dalian Medical University Dalian 116044, Liaoning, China.
Embryo implantation is regarded as a critical physiological process for the success of pregnancy. There are so many reports on the research of human chorionic gonadotropin (HCG) in artificial insemination, but the impact of HCG on endometrial receptivity has not been elucidated. Beta1, 4-Galactosyltransferase-I (β1,4-GalT-I) is ubiquitously expresses in human tissues with the exception of the brain.
View Article and Find Full Text PDFInt J Clin Exp Pathol
March 2016
Department of Oncology, The First Affiliated Hospital of Dalian Medical University Dalian 116011, China.
Lymph node metastasis is recognized as an important mode of liver cancer metastasis. Two hepatocarcinoma cell lines, Hca-F get high (75%) and Hca-P get low (25%) incidences of lymph node metastasis. Forkhead box M1 (FoxM1) is described as a major oncogenic transcription factor in tumor initiation, promotion, and progression.
View Article and Find Full Text PDFInt J Clin Exp Med
May 2015
Department of Neurosurgery, The First Affiliated Hospital of Dalian Medical University Dalian 116011, China.
Our present investigation focused on assessing the neuroprotective potential of baicalein (BAC) against diabetes-associated cognitive deficit (DACD) using a diabetic model and further figure out the potential molecular mechanisms. Diabetic rat model was established by streptozotocin (STZ). Vehicle or BAC by the doses of 2 and 4 mg/kg was intraperitoneally injected once a day for seven consecutive weeks.
View Article and Find Full Text PDFInt J Clin Exp Med
February 2015
Department of Thoracic Surgery, The First Affiliated Hospital of Dalian Medical University Dalian 116011, Liaoning, China.
It has been proposed that genetic factors contribute to the susceptibility of non-small cell lung cancer (NSCLC). The programmed death-1 (PD1) is an immunoinhibitory receptor belonging to the CD28/B7 family. The aim of this study is to investigate the relationship between PD-1.
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