3 results match your criteria: "The First Affiliated Hospital Shenzhen University[Affiliation]"

Protective Strategies for Pituitary Function During Endoscopic Transnasal Pituitary Adenoma Surgery: A Single-center Experience.

J Craniofac Surg

November 2024

Department of Neurosurgery, Pituitary Tumor Diagnosis and Treatment Research Center, The First Affiliated Hospital Shenzhen University, Shenzhen Second People's Hospital, Shenzhen, China.

Article Synopsis
  • - This study examined the effects of endoscopic transnasal pituitary adenoma surgery on pituitary function and aimed to identify factors that influence postoperative outcomes.
  • - An analysis of 306 patients' data revealed varying rates of postoperative hypopituitarism among different hormone axes, with the pituitary-thyroid and adrenal axes showing higher incidence rates post-surgery.
  • - Results indicated that larger tumors (giant adenomas) had a significantly greater impact on adrenal function, while no substantial difference in new hypopituitarism rates was observed after surgery between different tumor sizes.
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The Aryl Sulfide Synthesis via Sulfide Transfer.

Chemistry

June 2022

College of Materials Science and Opto-Electronic Technology &, Center of Materials Science and Optoelectronics Engineering &, CAS Center for Excellence in Topological Quantum Computation &, CAS Key Laboratory of Vacuum Physic, University of Chinese Academy of Sciences, Beijing, 100049, P. R. China.

Aryl sulfides are in great demands in drugs and materials sciences. To avoid using nucleophilic and noxious thiols, many efforts have been focused on exploring novel sulfide resources. Herein, a reductive Pd-catalyzed, Ni-mediated method to synthesize aryl sulfides via a sulfide transfer reaction is developed.

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Objective: To explore the surgical methods and clinical effect of endoscopic endonasal approaches for the treatment of invasive pituitary adenomas (IPAs).

Methods: A retrospective analysis was made of the clinical data of 74 patients (75 procedures) with IPAs treated by different endoscopic endonasal approaches at the Department of Neurosurgery, The First Affiliated Hospital of Shenzhen University from May 2014 to August 2017. The data include clinical manifestation, imaging features, surgical methods and complications, resection rate, cure rate, prognosis, and complications in different Knosp classifications and Hardy stages.

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