[Clinical and laboratory features of rheumatoid arthritis in men depending on testosterone levels].

Background:  It has been suggested that the presence of chronic immunoinflammatory rheumatic disease (CIRD) may be a factor that increases the likelihood of developing hypogonadism syndrome, and conversely, the presence of uncompensated testosterone deficiency may predispose to a greater risk of developing or more severe course of ICRD.

Aim:  To study the incidence of hypogonadism in men with rheumatoid arthritis (RA) and evaluate its impact on the course of RA and concomitant diseases.

Materials And Methods:  A one-time continuous study included 170 men with RA who were undergoing inpatient treatment at the Federal State Budgetary Institution NIIR named after.

[The Soviet health care: in searching unicorn].

The article review the book about the Soviet health care. The analysis of its content and main conclusions is presented. The book inflicts powerful blow on myth of numerous merits, achievements, progressiveness, impeccability and humanity of the Soviet health care.

[The stomatological care of schoolchildren in the Soviet Russia in 1920s: Succession of ideas].

The article considers historical interaction between the Soviet Russia and the Weimar Republic related to prevention of caries in children in 1920s and the role of P. G. Dauge in it.

[Prospects for personalized Helicobacter pylori eradication therapy. Pro et contra].

The article is devoted to debatable aspects of Helicobacter pylori eradication therapy. The eradication cancer-preventive effects are considered. A negative comorbidity between H.

[The characteristics of medical demographic indices in the Jewish autonomous oblast].

The research in the field of regional trends and risk factors related to population morbidity is considered as background of management decision-making in health care. The article presents the results of analysis of medical demographic indices and population health status in the Jewish Autonomous Oblast in 2000-2019. It is established that in in the Jewish Autonomous Oblast population size reduced by 35 100 people to 2019.

[The organizational forms of the Soviet Mongol cooperation in the area of medicine and health care in 1920s-1930s. Part II.The operation of expeditions of the Narkomzdrav of the RSFSR].

The article proceeds to analyze the results of the study of organizational forms of Soviet assistance to the Mongolian People's Republic in the field of medicine and health care. The characteristics of organization and activities of the first, second, and subsequent medical sanitary expeditions of the Narkomzdrav of the RSFSR in Mongolia. The new archival documents are introduced into scientific circulation, allowing to verify critical assessment of activities of the first expedition under direction of A.

[The organizational forms of the Soviet Mongol cooperation in the area of medicine and health care in 1920s-1930s. Part I. Formation of two approaches].

In 1920s - late 1980s, active cooperation between the USSR and Mongolia in the field of medicine and health care had been occurred. The Mongolian People's Republic was the first country to which the USSR exported its organization of health care system, using it as a means of geopolitical influence and instrument of the socialist transformation of traditional nomadic society. At the same time, assistance to Mongolia began when the USSR itself had not yet completed the organization of new health care system, including needed medical personnel and resources, receiving assistance from Germany and other European countries.

Analysis of Preferences in the Use of Fixed-Doses Combinations Antihypertensive Drugs in the Regions of Far-Eastern Federal District.

Background: Diseases characterized by elevated blood pressure are the most frequently diagnosed pathology among socially significant diseases in the Russian Federation. According to clinical recommendations of the Russian Medical Society for Arterial Hypertension 2010-2019, the use of two and more component drugs improves the compliance of patients to treatment. The purpose of this study was a comparative analysis of preferences in the usage of combined antihypertensive drugs in ten regions of the Far Eastern Federal District (FSD).

[Morphology of traces of large blood drops on a snow-covered surface with different bleeding source height].

Aim is to study morphology of the traces of a large drop of blood formed on snow-covered surface when it falls from different heights. In the experiment, we studied the morphology of blood drop traces fallen from 20, 50 and 100 cm on a just settled dry snow cover in a moderately frosty environment (-8 °C) Dropping from a height of up to 20 cm, a blood drop formed a cylindrical channel in the snow cover and spread out to form a disc-shaped element. However if the bleeding source was located at a 50 and 100 cm distance, an element close to a ball, consisting of blood crystals and ice was formed in the final section of the cylindrical channel.

Effect of MGHPPGP Peptide Administered during the Post-Traumatic Period on Morphometric Parameters of the Neocortex and Hippocampus, Hepatocytes, and Epithelium of the Tongue and Small Intestine in Rats.

The effect of glyproline-containing peptide MGHPPGP (Met-Glu-His-Phe-Pro-Gly-Pro) was studied in experiments on male Wistar rats with modeled traumatic brain injury. The peptide was administered intraperitoneally in a dose of 1 mg/kg in 3 h and on days 2, 3, 4, 5 after injury. We evaluated morphometric parameters of the epithelial cells of the tongue, small intestine, and liver cells (AgNOR staining), neuronal layers II and V of the neocortex of the parietal lobe and hippocampal CA1 field (staining with gallocyanin) were evaluated in the post-traumatic period.

[Influence of negative ambient temperature on the morphology of blood droplet traces].

The aim of this study was to identify the peculiarities of blood droplets on the street in frosty weather on the surfaces of objects with a negative temperature. The effect of negative ambient temperature (-19 °C) on the morphology of blood droplet traces was experimentally established. On cold trace surfaces, the droplet footprint was smaller, relatively flat and with wave-shaped edges; there was no splashing.

Russian consensus on exo- and endocrine pancreatic insufficiency after surgical treatment.

The Russian consensus on exo- and endocrine pancreatic insufficiency after surgical treatment was prepared on the initiative of the Russian "Pancreatic Club" on the Delphi method. His goal was to clarify and consolidate the opinions of specialists on the most relevant issues of diagnosis and treatment of exo- and endocrine insufficiency after surgical interventions on the pancreas. An interdisciplinary approach is provided by the participation of leading gastroenterologists and surgeons.

[Selection of optimal method of general anesthesia for intubation of nasolacrimal duct in young children].

Purpose: comparative assessment of safety and clinical efficacy of Sevoflurane and Halothane in general anesthesia for nasolacrimal duct intubation in children.

Material And Methods: Clinical results of nasolacrimal duct intubation in 288 children with persistent obstruction of tear duct were analyzed. A newly developed method of general anesthesia in the supine position was used for all cases.

Cytoprotective Effect of Peptide Sedatin, an Agonist of μ/δ-Opioid Receptors, on Primary Culture of Pulmonary Fibroblasts of Albino Rats under Conditions of Oxidative Stress.

We studied the effects of a synthetic analogue of dermorphin peptide sedatin on DNA synthesis, nucleolar apparatus, and parameters of free radical oxidation in the primary culture of pulmonary fibroblasts under conditions of oxidative stress. Oxidative stress significantly enhanced production of superoxide anion radical in the culture, sufficiently inhibited DNA synthesis in fibroblasts, and reduced the size of cell nuclei and parameters of the nucleolar apparatus. Sedatin prevented accumulation of free radical oxidation products and changes in karyometry parameters induced by oxidative stress.