Current state and future perspectives in the diagnosis of eyelid margin disease: clinical review.

The eyelid margin is vital to ocular surface integrity. Much peer-reviewed literature has been established in eyelid margin inflammation, better known as blepharitis. The purpose was to review and understand the impact of eyelid margin disease.

Eyelid margin disease (blepharitis and meibomian gland dysfunction): clinical review of evidence-based and emerging treatments.

Blepharitis is a common ophthalmic condition with multiple etiologies and no definitive, universal treatment. The treatment modalities for managing lid margin diseases vary depending on the disease's cause, location, and severity. For anterior blepharitis, management options include eyelid hygiene with warm compresses, eyelid scrubs, baby shampoo, and over-the-counter eyelid cleansers.

Macular Thickness Is Associated with Persistent Avascular Retina in Patients with a History of Untreated Retinopathy of Prematurity.

Objective:: To evaluate the relationship between central macular thickness (CMT) and the presence of persistent avascular retina (PAR) in previously premature children.

Methods:: 17 4-8 year olds with a history of retinopathy of prematurity (ROP) screening were recruited, and underwent OCT and ultra-widefield fluorescein angiography (UWFFA).

Results:: CMT was higher in PAR patients ( < 0.

End-to-End Impact of a Cloud-Based Surgical Planning System on Efficiency in Cataract Surgery: A Time-and-Motion Study.

Purpose: Inefficiencies from manual data entry and non-integration exist throughout the cataract surgery workflow. The aim of this study was to evaluate the impact of SMARTCataract, an innovative cloud-based digital surgical planning platform (SPS) on efficiency in preoperative (diagnostic workup, surgery planning), intraoperative, and postoperative phases of cataract surgery. The primary objective aimed to assess time and number of manual transcription data points (TPs) required for all pre-, intra-, and postoperative devices that integrate with the SPS and surgery planning time across three patient types (post-refractive, astigmatic, conventional).

Increased Incidence of Pseudotumor Cerebri Syndrome Among Users of Tetracycline Antibiotics.

Background: To determine whether the use of a tetracycline-class antibiotic is associated with an increased risk of developing pseudotumor cerebri syndrome (PTCS).

Methods: We identified patients in the University of Utah Health system who were prescribed a tetracycline-class antibiotic and determined what percentage of those individuals were subsequently diagnosed with PTCS secondary to tetracycline use. We compared this calculation to the number of patients with PTCS unrelated to tetracycline use.

Visual and Patient-Reported Outcomes of a Diffractive Trifocal Intraocular Lens Compared with Those of a Monofocal Intraocular Lens.

Purpose: To evaluate the effectiveness and safety of a trifocal intraocular lens (IOL), the TFNT00 (Alcon, Fort Worth, TX), versus a monofocal IOL, the SN60AT (Alcon).

Design: Food and Drug Administration-approved, prospective, multicenter, nonrandomized, parallel-group, assessor-masked, confirmatory trial.

Participants: Patients enrolled were 22 years of age or older with a diagnosis of bilateral cataract with planned removal by phacoemulsification with a clear corneal incision.

Novel Cross-Linked Ocular Bandage Gel Improves Reepithelialization After Photorefractive Keratectomy: A Randomized, Masked Prospective Study.

To compare, in a masked manner, a novel cross-linked hyaluronic acid ocular bandage gel (OBG) versus standard-of-care bandage contact lens (BCL) plus artificial tears with respect to safety and effectiveness in healing epithelial defects created for photorefractive keratectomy (PRK). This was a randomized, reading center-masked, exploratory study. Forty-five patients (myopic without significant anisometropia) scheduled for bilateral PRK (9-mm epithelial defect) were randomized post-PRK to treatment with OBG 8 times daily for 3 days, followed by 4 times daily for 11 days (Group 1); OBG 4 times daily for 14 days (Group 2); or BCL and artificial tears (Control).

Retrospective analysis of an intraoperative aberrometry database: a study investigating absolute prediction in eyes implanted with low cylinder power toric intraocular lenses.

Purpose: To evaluate the spherical equivalent outcomes of intraoperative aberrometry (IA) power calculations compared with the surgeons' preoperative power calculations in eyes implanted with AcrySof IQ T3 intraocular lenses (IOLs).

Patients And Methods: We assessed data collected by an IA system from multiple centers in the United States. Data was from patients who had undergone cataract extraction by phacoemulsification with the use of the Optiwave Refractive Analysis System and whose eyes had been implanted with model SN6AT3 (1.

A large retrospective database analysis comparing outcomes of intraoperative aberrometry with conventional preoperative planning.

Purpose: To evaluate differences between the absolute prediction error using an intraoperative aberrometry (IA) device for intraocular lens (IOL) power determination versus the error that would have resulted if the surgeon's preoperative plan had been followed.

Setting: Multiple centers in the United States.

Design: Retrospective analysis of data collected using an IA device.

Ability of a new crosslinked polymer ocular bandage gel to accelerate reepithelialization after photorefractive keratectomy.

Purpose: To evaluate the safety and performance of a crosslinked thiolated carboxymethyl hyaluronic acid liquid-gel (CMHA-S) ocular bandage gel in accelerating reepithelialization of corneal defects created for photorefractive keratectomy (PRK).

Setting: Three community-based clinical research sites.

Design: Prospective case series.

Comparison of stability between a modular intraocular lens system and a single-piece hydrophobic acrylic intraocular lens.

Purpose: To compare the movement of a modular intraocular lens (IOL) with that of a standard single-piece hydrophobic acrylic IOL in a human cadaver eye perfusion model.

Setting: Department of Ophthalmology, University of Colorado, Aurora, Colorado, USA.

Design: Experimental study.

Intraoperative aberrometry versus standard preoperative biometry and a toric IOL calculator for bilateral toric IOL implantation with a femtosecond laser: One-month results.

Purpose: To compare astigmatic outcomes in patients with bilateral cataracts having toric intraocular lens (IOL) implantation with intraoperative aberrometry measurements in 1 eye and standard power calculation and a toric IOL calculator with inked axis marking in the contralateral eye.

Setting: Twelve sites in the United States.

Design: Prospective cohort study.

The Anesthetic Implications of Aqueous Drainage Devices and Glaucoma: A Report of a Patient Undergoing Urgent Prone Cervical Decompression and Fusion.

The pathophysiology of glaucoma and perioperative visual loss is similar. A patient with glaucoma may be at increased risk of perioperative visual loss. For both, goals of management include optimizing ocular perfusion pressure and oxygen delivery.

Clinical study using a new phacoemulsification system with surgical intraocular pressure control.

Purpose: To compare cumulative dissipated energy (CDE), aspiration fluid used, and aspiration time during phacoemulsification cataract extraction using 2 surgical configurations.

Setting: Two clinical sites in the United States and 1 in Spain.

Design: Prospective randomized clinical case series.

Subluxated cataract lens surgery using sutured segments or rings and implantation of toric intraocular lenses.

Purpose: To evaluate the intraoperative performance and postoperative outcomes of toric intraocular lens (IOL) with suture ring implantation in adult patients with subluxated lenses.

Setting: Department of Ophthalmology, Kaiser Permanente, Santa Clara, California, and the Eye Institute of Utah, Salt Lake City, Utah, USA.

Design: Retrospective case review.

Evaluating Red Reflex and Surgeon Preference Between Nearly-Collimated and Focused Beam Microscope Illumination Systems.

Purpose: To evaluate the intensity and stability of the red reflex produced by ophthalmic surgical microscopes with nearly-collimated versus focused illumination systems and to assess surgeon preference in a simulated surgical setting.

Methods: This two-part evaluation consisted of postproduction surgical video analysis of red reflex intensity and a microscope use and preference survey completed by 13 experienced cataract surgeons. Survey responses were based on bench testing and experience in a simulated surgical setting.

Laceration and partial dislocation of LASIK flaps 7 and 4 years postoperatively with 20/20 visual acuity after repair.

Purpose: To report two cases of late ocular trauma resulting in laceration of corneal flaps 7 and 4 years (cases 1 and 2, respectively) after LASIK.

Methods: A 49-year-old man sustained laceration of the flap and interface foreign body debris from construction material in the right eye 7 years after uneventful LASIK (case 1). A 33-year-old man had partial dislocation of the flap 4 years after LASIK in the left eye (case 2) due to a penetrating wood chip accident.

Analysis of intraocular lens power calculation for eyes with previous myopic LASIK.

Purpose: To evaluate the effectiveness of a manual keratometry (K) adjusted value for intraocular lens (IOL) power calculation in patients who underwent cataract surgery following previous myopic LASIK.

Methods: Sixteen eyes of 14 consecutive patients who underwent cataract surgery after previous LASIK were evaluated retrospectively. All IOL powers were calculated using an adjusted K value (K minus 1.

Conventional and wavefront-guided myopic LASIK retreatment.

Purpose: To assess the clinical outcomes of conventional and wavefront-guided myopic laser in situ keratomileusis (LASIK) retreatment.

Design: Retrospective, nonrandomized case series.

Methods: The study comprised a cohort of 97 eyes having LASIK retreatment for residual myopia after primary LASIK.

Laser in situ keratomileusis for primary and secondary mixed astigmatism.

Purpose: To evaluate and compare the efficacy, predictability, and safety of LASIK in the correction of primary and secondary mixed astigmatism after previous LASIK surgery.

Design: Retrospective, comparative case series.

Methods: The retrospective study included 118 eyes having LASIK with the LADARVison 4000 excimer laser (Alcon Surgical, Orlando, Florida) to correct mixed astigmatism.

Laser in situ keratomileusis for primary hyperopia.

Purpose: To evaluate the efficacy, predictability, stability, and safety of hyperopic laser in situ keratomileusis (H-LASIK) over a 24-month period and analyze topographic changes after H-LASIK to assess topographic pseudokeratectasia (TPKE) following H-LASIK.

Setting: Eye Institute of Utah, Salt Lake City, Utah, USA.

Methods: This prospective study included 139 eyes of 77 patients having H-LASIK for primary hyperopia.

Late-onset idiopathic diffuse lamellar keratitis after laser in situ keratomileusis.

We report a case of late-onset diffuse lamellar keratitis (DLK) in the left eye of a 56-year-old white woman 3 years after uneventful bilateral laser in situ keratomileusis (LASIK). Slitlamp examination revealed stage 3 DLK with diffuse, multifocal, dot-like, and granular haze in the interface. The DLK did not have an obvious causative agent such as trauma or epithelial defects and responded rapidly to topical corticosteroid therapy.

Inferior corneal steepening after a partial flap without laser ablation mimicking corneal ectasia.

We report a patient with inferior steepening mimicking corneal ectasia that developed after 2 incomplete microkeratome cuts (partial or short flap) without laser ablation.

Interface fluid after laser in situ keratomileusis.

Purpose: To describe a case of interface fluid after laser in situ keratomileusis (LASIK) and review the literature on this rare complication after LASIK.

Methods: We present a case report and literature review. Articles for this review were chosen from electronic database and manual literature searches.

Laser in situ keratomileusis with the VISX Star laser for myopia over -10.0 diopters.

Purpose: To evaluate the efficacy, predictability, stability, and safety of laser in situ keratomileusis (LASIK) for myopia over -10.00 diopters (D).

Setting: The Eye Institute of Utah, Salt Lake City, Utah, USA.