9 results match your criteria: "The Erlanger Heart and Lung Institute[Affiliation]"
Associations of Sarcopenia and Body Composition Measures With Mortality After Transcatheter Aortic Valve Replacement.
Circ Cardiovasc Interv
February 2024
Department of Medicine, Division of Cardiology (R.P., R.R.M., N.J., B.R.L.), Vanderbilt University Medical Center, Nashville, TN.
Article Synopsis
- Frailty linked to worse outcomes post-transcatheter aortic valve replacement (TAVR) and is often underpinned by sarcopenia, which includes muscle mass, strength, and performance, though their impact on TAVR outcomes hasn't been fully studied.
- In a study of 445 patients with severe aortic stenosis, significant percentages were found to have slow gait (56%), weak grip (59%), and low muscle mass (42%); only slower gait speed showed a clear link to increased mortality after TAVR.
- The research indicates that while overall body fat measurements and sarcopenia criteria influence mortality risk, lower visceral fat and slow gait speed are main factors affecting post-TAVR death rates.
Response by Zeitler et al to Letter Regarding Article, "Comparative Effectiveness of Left Atrial Appendage Occlusion Versus Oral Anticoagulation by Sex".
Circulation
August 2023
Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC (S.M.A.-K.).
How Can Preprocedure Workflows in LAAO Affect Diversity and Inclusion Efforts?: The Limitations of Registries.
JACC Cardiovasc Interv
June 2023
Division of Cardiology, Department of Medicine, University of Tennessee-Chattanooga, The Erlanger Heart and Lung Institute, Chattanooga, Tennessee, USA. Electronic address:
Options to Improve Quality of Life for Aortic Stenosis: "No Decision About Me, Without Me".
J Am Coll Cardiol
February 2023
Cardiovascular Medicine, Baylor Scott and White, The Heart Hospital Plano, Plano, Texas, USA.
Left Atrial Appendage Occlusion: Current Advances and Remaining Challenges.
JACC Adv
December 2022
Department of Cardiology, Mayo Clinic School of Medicine, Rochester, Minnesota, USA.
The field of left atrial appendage occlusion is rapidly evolving. However, several issues remain including the limited randomized efficacy data, peri-device leak, device-related thrombus, and the ongoing refinement of procedural techniques. In this article, we provide a contemporary overview of left atrial appendage occlusion focusing on 4 key remaining challenges: efficacy data, peri-device leak, device-related thrombus, and procedural optimization.
View Article and Find Full Text PDFWhat matters most to patients with severe aortic stenosis when choosing treatment? Framing the conversation for shared decision making.
PLoS One
August 2022
Department of Cardiovascular Medicine, The Erlanger Heart and Lung Institute, Chattanooga, Tennessee, United States of America.
Background: Guidelines recommend including the patient's values and preferences when choosing treatment for severe aortic stenosis (sAS). However, little is known about what matters most to patients as they develop treatment preferences. Our objective was to identify, prioritize, and organize patient-reported goals and features of treatment for sAS.
View Article and Find Full Text PDFBackground Left ventricular hypertrophy (LVH) is associated with increased mortality risk and rehospitalization after transcatheter aortic valve replacement among those with severe aortic stenosis. Whether cardiac troponin (cTnT) and NT-proBNP (N-terminal pro-B-type natriuretic peptide) risk stratify patients with aortic stenosis and without LVH is unknown. Methods and Results In a multicenter prospective registry of 923 patients with severe aortic stenosis undergoing transcatheter aortic valve replacement, we included 674 with core-laboratory-measured LV mass index, cTnT, and NT-proBNP.
View Article and Find Full Text PDFPredicting When Women Will Achieve Equitable Representation in Four Specialties: The WHEN Study.
Am J Med
May 2022
Division of Cardiovascular Medicine, The Erlanger Heart and Lung Institute, Chattanooga, TN. Electronic address:
Background: For 2 decades, women have made up nearly half of medical school graduates, yet this has not translated to equity in promotion. We compare historical trends in the academic career pipeline among 4 specialties by sex.
Methods: Using the Association of American Medical Colleges database, faculty sex and rank were examined in oncology, gastroenterology, cardiovascular medicine, and general surgery for the years 2000 and 2020.
Evaluating Medical Therapy for Calcific Aortic Stenosis: JACC State-of-the-Art Review.
J Am Coll Cardiol
December 2021
Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec-Université Laval, Québec City, Québec, Canada.
Article Synopsis
- Despite the existence of potential treatment targets for calcific aortic stenosis (AS), effective medical therapies have not yet been established, necessitating collaboration among various stakeholders.
- The review covers the disease's underlying biology, promising drug targets, as well as the need to identify specific patient groups for clinical trials, emphasizing the importance of patient input in trial design.
- It highlights the advantages of using clinical trial networks and platform trials to efficiently test and develop new medical therapies, aiming to provide clear guidance for future research in this area.