108 results match your criteria: "The Ear Institute[Affiliation]"
Brain Sci
January 2025
Department of Neurology, National Hospital for Neurology and Neurosurgery, London WC1N 3BG, UK.
Acute vertigo or dizziness is a frequent presentation to the emergency department (ED), making up between 2.1% and 4.4% of all consultations.
View Article and Find Full Text PDFAgeing Res Rev
December 2024
Division of Psychiatry, University College London, Maple House, 149 Tottenham Court Road, London W1T 7NF, UK; North London NHS Foundation Trust, London, 4 St Pancras Way, London NW1 0PE, UK. Electronic address:
Background And Objective: People with adult-onset hearing loss (AoHL) are at increased dementia risk. In this study, we explore potential aetiological mechanisms by synthesising the evidence on the association between AoHL and neuropathological, cerebrospinal fluid (CSF), blood and imaging biomarkers of dementia.
Methods: We systematically searched electronic databases from inception to 30 April 2024 for cross-sectional and longitudinal studies, including quantitative data on the association between AoHL and dementia biomarkers.
PLoS Negl Trop Dis
December 2024
Department of Disease Control, London School of Hygiene & Tropical Medicine, London, United Kingdom.
J Neurol
December 2024
The Ear Institute, University College London, London, UK.
Background: Stroke is the second leading cause of disability worldwide. Stroke results in focal neurological deficit and often leads to auditory problems due to its impact on the auditory pathway. Altered connections in the auditory pathway, caused by stroke, can result in hearing difficulties ranging from impaired sound detection to altered auditory perception.
View Article and Find Full Text PDFBrain Commun
October 2024
Department of Clinical and Movement Neurosciences, University College London Queen Square Institute of Neurology, London WC1N 3BG, UK.
Epilepsy Behav
November 2024
School of Medicine, Aristotle University of Thessaloniki University Campus, Thessaloniki 54124, Greece.
Q J Exp Psychol (Hove)
November 2024
Dementia Research Centre, UCL Queen Square Institute of Neurology, UCL, London, UK.
Front Neurol
August 2024
Department of Clinical and Movement Neurosciences, Institute of Neurology, University College London, London, United Kingdom.
Background: Vestibular Migraine (VM) is a prevalent vestibular disorder, affecting up to 2.7% of the general population. Despite the establishment of diagnostic criteria by the Bárány Society and its inclusion in the International Classification of Headache Disorders, the clinical diagnosis of VM remains challenging due to its complex pathophysiology and symptom overlap with other dizziness disorders.
View Article and Find Full Text PDFFront Hum Neurosci
August 2024
The Ear Institute, University College London, London, United Kingdom.
[This corrects the article DOI: 10.3389/fnhum.2024.
View Article and Find Full Text PDFSurg Endosc
October 2024
Digestive Diseases & Surgical Institute, Cleveland Clinic London, London, UK.
Front Hum Neurosci
June 2024
The Ear Institute, University College London, London, United Kingdom.
Background: For adults with auditory processing disorder (APD), listening and communicating can be difficult, potentially leading to social isolation, depression, employment difficulties and certainly reducing the quality of life. Despite existing practice guidelines suggesting treatments, the efficacy of these interventions remains uncertain due to a lack of comprehensive reviews. This systematic review and meta-analysis aim to establish current evidence on the effectiveness of interventions for APD in adults, addressing the urgent need for clarity in the field.
View Article and Find Full Text PDFAgeing Res Rev
July 2024
Division of Psychiatry, University College London, 6th Floor, Maple House, 149 Tottenham Court Road, London W1T 7NF, England. Electronic address:
Background: We comprehensively summarized the cohort evidence to date on adult-onset hearing loss as risk factor for incident cognitive impairment and dementia, and examined the evidence for dose-response, risk for various dementia subtypes, and other moderators. Previous meta-analyses were less comprehensive.
Methods: We included cohort studies with participants without dementia and with hearing assessments at baseline, minimum 2 years follow-up and incident cognitive outcomes.
Int J Audiol
March 2024
The Ear Institute, University College London, London, UK.
Objective: To investigate (1) the current level of awareness and knowledge on Auditory Processing Disorder (APD) among Audiologists and other hearing healthcare professionals; (2) current practices in screening, diagnosis, and management of APD in children and adults across the UK; (3) professional's acceptance of APD assessment and diagnosis.
Design: An online survey was disseminated through the British Academy of Audiology and ENT UK.
Study Sample: A total of 191 hearing healthcare professionals responded to the survey.
J Neurol
January 2024
Comprehensive Stroke Service, National Hospital for Neurology and Neurosurgery, Queen Square, London, UK.
J Neurol
December 2023
Comprehensive Stroke Service, National Hospital for Neurology and Neurosurgery, Queen Square, London, UK.
Eur Radiol
November 2023
School of Biomedical Engineering & Imaging Sciences, King's College London, London, UK.
J Neurol Sci
December 2022
Centre for Vestibular and Behavioural Neurosciences, Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, London, UK; The Ear Institute, University College London, London, UK. Electronic address:
Background And Objectives: Saccades, rapid movements of the eyes towards a visual or remembered target, are useful in understanding the healthy brain and the pathology of neurological conditions such as progressive supranuclear palsy (PSP). We set out to investigate the parameters of horizontal reflexive and volitional saccades, both visually guided and memory-guided, over a 1 min epoch in healthy individuals and PSP patients.
Methods: An experimental paradigm tested reflexive, volitional visually guided, and volitional memory-guided saccades in young healthy controls (n = 14; 20-31 years), PSP patients (n = 11; 46-75 years) and older age-matched healthy controls (n = 6; 56-71 years).
Front Neurol
September 2022
The Ear Institute, Faculty of Brain Sciences, University College London, London, United Kingdom.
Vestibular Migraine (VM) is the most common cause of non-positional episodic vestibular symptoms. Patients with VM commonly report increased motion sensitivity, suggesting that vestibular responses to head movement may identify changes specific to VM patients. Here we explore whether the vestibulo-ocular reflex (VOR) gain alters in response to a clinical "headshake" maneuver in patients with VM.
View Article and Find Full Text PDFJ Neurol Sci
November 2022
Centre for Vestibular and Behavioural Neurosciences, Department of Clinical and Movement Neurosciences, Institute of Neurology, University College London, Queen Square, London, UK; The Ear Institute, University College London, London, UK; Department of Neuro-otology, Royal national ENT and Eastman Dental Hospitals, University College London Hospitals, London, UK. Electronic address:
The video head impulse test (vHIT) assesses the vestibulo-ocular reflex (VOR) during a rapid high-velocity low amplitude (10°-20°) head rotation. Patients with peripheral vestibulopathy have a reduced VOR gain with corrective catch-up saccades during the head turn. There are several pitfalls, mainly technical, which may interfere with interpretation of vHIT data.
View Article and Find Full Text PDFSci Rep
August 2022
The Ear Institute, University College London, London, England, UK.
The cochlea decomposes sounds into separate frequency channels, from which the auditory brain must reconstruct the auditory scene. To do this the auditory system must make decisions about which frequency information should be grouped together, and which should remain distinct. Two key cues for grouping are temporal coherence, resulting from coherent changes in power across frequency, and temporal predictability, resulting from regular or predictable changes over time.
View Article and Find Full Text PDFNeurology
November 2022
From the Ear Institute (N.K., D.-E.B.), Stroke Research Centre (D.W.), Department of Brain Repair and Rehabilitation, Queen Square Institute of Neurology (A.A.M.), and Department of Statistical Science (M.P.), University College London; and National Institute for Health and Care Research (N.K., D.-E.B.), University College London Hospitals Biomedical Research Centre (Deafness and Hearing Problems Theme), London; Southampton School of Medicine (A.A.M.), University of Southampton, UK.
Background And Objectives: Infratentorial superficial siderosis (iSS) is a rare but disabling neurologic condition characterized by progressive hearing loss and balance and mobility problems. The functional decline in these neurologic domains with iSS progression is likely to adversely affect health-related quality of life (HRQoL). We studied the HRQoL of adults with iSS using 2 common generic HRQoL measures (Health Utilities Index Mark III [HUI3] and EuroQoL EQ5D [5 Level]) to determine the most affected domains and evaluate the association between HRQoL scores and disease duration.
View Article and Find Full Text PDFOtol Neurotol
March 2022
The Ear Institute, Faculty of Brain Sciences, University College London.
Introduction: Vestibular migraine (VM) is a common condition; individuals experience dizziness with migraine symptoms. Vestibular rehabilitation therapy (VRT) has been reported as an effective treatment for VM, however, evidence is limited. VM and traumatic brain injury (TBI) can co-occur, and some suggest that TBI can induce VM.
View Article and Find Full Text PDFJ Biophotonics
April 2022
School of Biomedical Engineering & Imaging Sciences, King's College London, London, UK.
Neuro-oncology surgery would benefit from detailed intraoperative tissue characterization provided by noncontact, contrast-agent-free, noninvasive optical imaging methods. In-depth knowledge of target tissue optical properties across a wide-wavelength spectrum could inform the design of optical imaging and computational methods to enable robust tissue analysis during surgery. We adapted a dual-beam integrating sphere to analyse small tissue samples and investigated ex vivo optical properties of five types of human brain tumour (meningioma, pituitary adenoma, schwannoma, low- and high-grade glioma) and nine different types of healthy brain tissue across a wavelength spectrum of 400 to 1800 nm.
View Article and Find Full Text PDFJ Neurol
May 2022
Department of Clinical and Movement Neurosciences, Centre for Vestibular and Behavioural Neuroscience, Institute of Neurology, University College London, London, UK.
Public Health Res Pract
December 2021
Department of Speech and Hearing Sciences, University of Washington, Seattle, US.
Objective: A high prevalence of hearing loss in older adults contrasts with a small proportion of people who seek help. Emerging developments in hearing healthcare (HHC) could reduce costs but may not increase access. This study evaluated older adults' perceptions of current and future HHC services in Australia, England, US and Canada to explore potential levers and system improvements.
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