Modeling intrinsic factors of inclusive engagement in citizen science: Insights from the participants' survey analysis of CSI-COP.

Inclusive citizen science, an emerging field, has seen extensive research. Prior studies primarily concentrated on creating theoretical models and practical strategies for diversifying citizen science (CS) projects. These studies relied on ethical frameworks or post-project empirical observations.

Case Study of Large Three-Dimensional-Printed Slider with Conformal Cooling for High-Pressure Die Casting.

Metal three-dimensional (3D) printing technology brings several benefits to the field of high-pressure die casting of aluminum, which enhances its development. The associated conformal cooling application is already commonly used where there is a need to improve the quality of castings, increase tool life, or reduce the production cycle. However, will this technology withstand the production of a large part (∼270 × 270 × 200 mm), which will be used directly in the serial production of engine blocks? This article describes a slider with a conformal cooling case study, which was redesigned and manufactured using the laser powder bed fusion (L-PBF) method.

Overview and Comparison of PLA Filaments Commercially Available in Europe for FFF Technology.

This study presents a comprehensive techno-economic analysis of PLA materials for fused filament fabrication (FFF) from eight European manufacturers. The comparison involved rigorous experimental assessments of the mechanical properties, dimensional accuracy, and print quality using standardized methods and equipment such as tensile and CT testing. What makes this study unique is the consistent methodology applied, considering factors such as material color, printing temperature, printing orientation, filament diameter, and printer selection, to ensure meaningful and reliable results.

Impact of Personal Protective Equipment on the Quality of Chest Compressions in Prehospital Care: A Prospective Randomized Crossover Study.

Introduction: The use of personal protective equipment (PPE) in prehospital emergency care has significantly increased since the onset of the coronavirus disease 2019 (COVID-19) pandemic. Several studies investigating the potential effects of PPE use by Emergency Medical Service providers on the quality of chest compressions during resuscitation have been inconclusive.

Study Objectives: This study aimed to determine whether the use of PPE affects the quality of chest compressions or influences select physiological biomarkers that are associated with stress.

SPECTROMETRY OF HIGH-ENERGY PHOTONS ON HIGH MOUNTAIN OBSERVATORY LOMNICKÝ ŠTÍT DURING THUNDERSTORMS.

Lomnický štít, Slovakia, 2634 m above sea level, is known to be a place of extreme electric fields measured during thunderstorms and is thus a suitable place for thunderstorm-related ionising radiation research. We present one of the strongest Thunderstorm ground enhancements (TGE) ever detected, which occurred on 12 September 2021. The TGE was detected with the SEVAN detector and also with the new Georadis RT-56 large volume gamma spectrometer.

Study of the Two-Line Element Accuracy by 1U CubeSat with a GPS Receiver.

There is a common practice to calculate orbital trajectories of space objects like satellites and space debris using Two-Line Element Sets (TLEs). However, TLEs provide rather coarse parameters for fine orbit computation and their precision varies with age of their issue and position of the satellite. The paper evaluates such induced position determination error using the comparison of a position calculated from TLE data for a small CubeSat class satellite and a position obtained from the on-board custom GPS receiver that is a part of such satellite payload.

Mechanical and Microstructural Anisotropy of Laser Powder Bed Fusion 316L Stainless Steel.

This paper aims at an in-depth and comprehensive analysis of mechanical and microstructural properties of AISI 316L austenitic stainless steel (W. Nr. 1.

Glyphosate Interaction with eEF1α1 Indicates Altered Protein Synthesis: Evidence for Reduced Spermatogenesis and Cytostatic Effect.

The broad-spectrum herbicide, glyphosate, is considered safe for animals because it selectively affects the shikimate pathway that is specific to plants and microorganisms. We sought a previously unknown mechanism to explain the concerns that glyphosate exposure can negatively affect animals, including humans. Computer modeling showed a probable interaction between glyphosate and eukaryotic translation elongation factor 1 subunit alpha 1 (eEF1α1), which was confirmed by microcalorimetry.

Optimization of Process Parameters for Additively Produced Tool Steel 1.2709 with a Layer Thickness of 100 μm.

The purpose of this study was to find and optimize the process parameters of producing tool steel 1.2709 at a layer thickness of 100 μm by DMLS (Direct Metal Laser Sintering). HPDC (High Pressure Die Casting) tools are printed from this material.

Identification of Eukaryotic Translation Elongation Factor 1-α 1 Gamendazole-Binding Site for Binding of 3-Hydroxy-4(1 H)-quinolinones as Novel Ligands with Anticancer Activity.

Here, we have identified the interaction site of the contraceptive drug gamendazole using computational modeling. The drug was previously described as a ligand for eukaryotic translation elongation factor 1-α 1 (eEF1A1) and found to be a potential target site for derivatives of 2-phenyl-3-hydroxy-4(1 H)-quinolinones (3-HQs), which exhibit anticancer activity. The interaction of this class of derivatives of 3-HQs with eEF1A1 inside cancer cells was confirmed via pull-down assay.

Significant improvement of biocompatibility of polypropylene mesh for incisional hernia repair by using poly-ε-caprolactone nanofibers functionalized with thrombocyte-rich solution.

Incisional hernia is the most common postoperative complication, affecting up to 20% of patients after abdominal surgery. Insertion of a synthetic surgical mesh has become the standard of care in ventral hernia repair. However, the implementation of a mesh does not reduce the risk of recurrence and the onset of hernia recurrence is only delayed by 2-3 years.

Cell penetration to nanofibrous scaffolds: Forcespinning®, an alternative approach for fabricating 3D nanofibers.

Cell infiltration is a critical parameter for the successful development of 3D matrices for tissue engineering. Application of electrospun nanofibers in tissue engineering has recently attracted much attention. Notwithstanding several of their advantages, small pore size and small thickness of the electrospun layer limit their application for development of 3D scaffolds.