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Hemostasis in children with dysbacteriosis in chronic constipation.

Clin Appl Thromb Hemost

October 2001

Krasnoyarsk State Medical Academy, The City's Clinical Hospital No. 20, The Department of Children Surgery of the Advanced Medical Courses, Russia.

The purpose of the study was to investigate hemostasis in children with dysbacteriosis disturbance in chronic constipation. The disturbance of factors in the inner mechanism of blood coagulation (VII, IX, XI, XII) in compensated chronic constipation was defined based on the reduction in colon bacillus levels. We observed hypocoagulation caused by the reduced activity of the prothrombin complex factors, disaggregate thrombocytopathy, and endotheliosis with fibrinolysis inhibition in subcompensated chronic colostasis with continuous reduction of colon bacillus levels and pathogenic microflora appearance.

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