1 results match your criteria: "The Chinese University of Hong Kong (M.J.[Affiliation]"
Endothelial Serotonin Receptor 1B Acts as a Mechanosensor to Drive Atherosclerosis.
Circ Res
March 2025
Faculty of Medicine, School of Biomedical Sciences, The Chinese University of Hong Kong (M.J., H.D., C.W.L., Y.X., X.Y., Yu Huang).
Background: Atherosclerosis is characterized by the accumulation of fatty and fibrotic plaques, which preferentially develop at curvatures and branches along the arterial trees that are exposed to disturbed flow. However, the mechanisms by which endothelial cells sense disturbed flow are still unclear.
Methods: The partial carotid ligation mouse model was used to investigate disturbed flow-induced atherogenesis.