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Protective effect of nitric oxide on hepatopulmonary syndrome from ischemia-reperfusion injury.

World J Gastroenterol

July 2012

Department of Hepatobiliary Surgery and Liver Transplant Center, Jinan Military Region, The Chinese PLA 401st Hospital, Qingdao 266071, Shandong Province, China.

Aim: To evaluate immunological protection of nitric oxide (NO) in hepatopulmonary syndrome and probable mechanisms of ischemia-reperfusion (IR) injury in rat liver transplantation.

Methods: Sixty-six healthy male Wistar rats were randomly divided into three groups (11 donor/recipient pairs). In group II, organ preservation solution was lactated Ringer's solution with heparin 10, 000/μL at 4 °C.

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