2 results match your criteria: "The Catholic University of KoreaSeoul[Affiliation]"

GRIM-19 Restricts HCV Replication by Attenuating Intracellular Lipid Accumulation.

Front Microbiol

April 2017

The Catholic University Liver Research Center and WHO Collaborating Center of Viral Hepatitis, The Catholic University of KoreaSeoul, South Korea.

Gene-associated with retinoid-interferon-induced mortality 19 (GRIM-19) targets multiple signaling pathways involved in cell death and growth. However, the role of GRIM-19 in the pathogenesis of hepatitis virus infections remains unexplored. Here, we investigated the restrictive effects of GRIM-19 on the replication of hepatitis C virus (HCV).

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Increased Expression of Osteopontin in Retinal Degeneration Induced by Blue Light-Emitting Diode Exposure in Mice.

Front Mol Neurosci

August 2016

Department of Anatomy, College of Medicine, The Catholic University of KoreaSeoul, Korea; Catholic Neuroscience Institute, College of Medicine, The Catholic University of KoreaSeoul, Korea; Catholic Institute for Applied Anatomy, College of Medicine, The Catholic University of KoreaSeoul, Korea.

Osteopontin (OPN) is a multifunctional adhesive glycoprotein that is implicated in a variety of pro-inflammatory as well as neuroprotective and repair-promoting effects in the brain. As a first step towards understanding the role of OPN in retinal degeneration (RD), we examined changes in OPN expression in a mouse model of RD induced by exposure to a blue light-emitting diode (LED). RD was induced in BALB/c mice by exposure to a blue LED (460 nm) for 2 h.

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