5 results match your criteria: "The Catholic University Korea[Affiliation]"
Isolation and characterization of cancer-associated fibroblasts in the tumor microenvironment of hepatocellular carcinoma.
J Liver Cancer
September 2023
The Catholic University Liver Research Center and POSTECH-Catholic Biomedical Engineering Institute, College of Medicine, The Catholic University Korea, Seoul, Korea.
Background/aim: Cancer-associated fibroblasts (CAFs) play an immunosuppressive role in the tumor microenvironment (TME) of human cancers; however, their characteristics and role in hepatocellular carcinoma (HCC) remain to be elucidated.
Methods: Nine tumor and surrounding liver tissue samples from patients with HCC who underwent surgery were used to isolate patient-derived CAFs. Cell morphology was observed using an optical microscope after culture, and cell phenotypes were evaluated using flow cytometry and immunoblotting.
Non-obese non-alcoholic fatty liver disease (NAFLD) in Asia: an international registry study.
Metabolism
January 2022
Division of Gastroenterology and Hepatology, National University Health System, Singapore; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore. Electronic address:
Background: A significant proportion of the non-alcoholic fatty liver disease (NAFLD) population is non-obese. Prior studies reporting the severity of NAFLD amongst non-obese patients were heterogenous. Our study, using data from the largest biopsy-proven NAFLD international registry within Asia, aims to characterize the demographic, metabolic and histological differences between non-obese and obese NAFLD patients.
View Article and Find Full Text PDFOptimizing Use of Nonalcoholic Fatty Liver Disease Fibrosis Score, Fibrosis-4 Score, and Liver Stiffness Measurement to Identify Patients With Advanced Fibrosis.
Clin Gastroenterol Hepatol
November 2019
Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong.
Background & Aims: Measuring liver stiffness only in patients with indeterminate or high nonalcoholic fatty liver disease (NAFLD) fibrosis scores (called a 2-step approach) was reported to reduce indeterminate or discordant results while maintaining the accuracy to identify patients with advanced fibrosis. We aimed to validate this approach using data collected from the Gut and Obesity in Asia Workgroup.
Methods: We performed a retrospective analysis of data from 759 patients with biopsy-proven NAFLD (24% with advanced fibrosis), seen at 10 centers in 9 countries in Asia, from 2006 through 2018.
Clinical features and treatment of nonalcoholic fatty liver disease across the Asia Pacific region-the GO ASIA initiative.
Aliment Pharmacol Ther
March 2018
The Chinese University of Hong Kong, Hong Kong, China.
Background: The Gut and Obesity Asia (GO ASIA) workgroup was formed to study the relationships between obesity and gastrointestinal diseases in the Asia Pacific region.
Aim: To study factors associated with nonalcoholic steatohepatitis (NASH) and advanced fibrosis, and medical treatment of biopsy-proven nonalcoholic fatty liver disease (NAFLD) patients.
Methods: Retrospective study of biopsy-proven NAFLD patients from centres in the GO ASIA Workgroup.
A pilot study of the osseointegration potential of a surface-treated mini-implant: bone contact of implants retrieved from patients.
World J Orthod
April 2013
Division of Oral and Maxillofacial Surgery, Department of Dentistry, The Catholic University Korea, Uijonbu St Mary's Hospital, Seoul, South Korea.
Article Synopsis
- The study aimed to assess how well surface-treated mini-implants integrate with bone by measuring bone-to-implant contact (BIC).
- Five mini-implants from four patients were analyzed, showing an average age of 38.1 years and treatment lasting about 11.4 months.
- The results indicated a significant bone cell adherence to the implants, with a mean BIC of 52.6%, suggesting that these surface-treated implants have good potential for osseointegration.