Xanthinuria in a familial group of Munchkin cats and an unrelated domestic shorthair cat.

Case Series Summary: Four confirmed cases of xanthinuria in cats, and one suspected case based on pedigree analysis, were identified. Clinical presentations varied and included haematuria, pollakiuria, dysuria, and urethral and ureteral obstruction. All cats had upper urinary tract uroliths.

Frequency of diabetic remission, predictors of remission and survival in cats using a low-cost, moderate-intensity, home-monitoring protocol and twice-daily glargine.

Objectives: The aim of the present study was to retrospectively assess remission rates and survival in diabetic cats managed using a moderate-intensity, low-cost protocol of home blood glucose measurements and insulin adjustment by clients of a cat-only practice, and to determine if predictors of remission, relapse or survival could be identified.

Methods: The records of a cat-only practice were used to identify 174 cats with newly diagnosed diabetes managed using only pre-insulin home blood glucose measurements for insulin dose adjustments based on a protocol provided to clients aimed at maintaining pre-insulin blood glucose in the range of 6.5-11.

Cutaneous lesions and clinical outcomes in five cats after frunevetmab injections.

Case Series Summary: This case series describes five cats with cutaneous adverse events after subcutaneous administration of frunevetmab, a felinised anti-nerve growth factor monoclonal antibody, including histopathological findings in one case. All cats displayed moderate to severe pruritus resulting in self-trauma to the neck and/or head, causing lesions ranging from superficial dermatitis to alopecia and ulcerations. There were no reactions at the injection sites.

Measures of insulin sensitivity, leptin, and adiponectin concentrations in cats in diabetic remission compared to healthy control cats.

Objectives: Firstly, to compare differences in insulin, adiponectin, leptin, and measures of insulin sensitivity between diabetic cats in remission and healthy control cats, and determine whether these are predictors of diabetic relapse. Secondly, to determine if these hormones are associated with serum metabolites known to differ between groups. Thirdly, if any of the hormonal or identified metabolites are associated with measures of insulin sensitivity.

Feline immunodeficiency virus (FIV) infection in domestic pet cats in Australia and New Zealand: Guidelines for diagnosis, prevention and management.

Despite the passage of over 30 years since its discovery, the importance of feline immunodeficiency virus (FIV) on the health and longevity of infected domestic cats is hotly debated amongst feline experts. Notwithstanding the absence of good quality information, Australian and New Zealand (NZ) veterinarians should aim to minimise the exposure of cats to FIV. The most reliable way to achieve this goal is to recommend that all pet cats are kept exclusively indoors, or with secure outdoor access (e.

2021 AAFP Feline Senior Care Guidelines.

The '2021 AAFP Feline Senior Care Guidelines' are authored by a Task Force of experts in feline clinical medicine and serve as an update and extension of those published in 2009. They emphasize the individual patient evaluation and the process of aging, with references to other feline practice guidelines for a more complete discussion of specific diseases. Focusing on each cat encourages and empowers the owner to become a part of the cat's care every step of the way.

Metabolic Profiling of Diabetic Cats in Remission.

The majority of diabetic cats in remission have abnormal glucose tolerance, and approximately one third relapse within 1 year. Greater understanding of the metabolic characteristics of diabetic cats in remission, and predictors of relapse is required to effectively monitor and manage these cats. To identify and compare differences in plasma metabolites between diabetic cats in remission and healthy control cats using a metabolomics approach.

The environmental needs of many Australian pet cats are not being met.

Objectives: The aim of this study was to investigate whether Australian cat owners are effectively meeting their cats' environmental needs and to identify areas of deficiency that may have an impact on the cats' health and welfare.

Methods: An online survey investigating lifestyle factors and provision of environmental resources was distributed to Australian cat owners.

Results: In total, 12,010 respondents, representing cat-owning households, completed the survey.

2019 AAFP Feline Zoonoses Guidelines.

Aim: The overarching purpose of the 2019 AAFP Feline Zoonoses Guidelines (hereafter referred to as the 'Guidelines') is to provide accurate information about feline zoonotic diseases to owners, physicians and veterinarians to allow logical decisions to be made concerning cat ownership.

Scope And Accessibility: The Panelists are physicians and veterinarians who worked closely together in an attempt to make these Guidelines a document that can be used to support the International One Health movement. This version of the Guidelines builds upon the first feline zoonosis panel report, published in 2003 ( catvets.

Self-induced, noninflammatory alopecia associated with infestation with Lynxacarus radovskyi: a series of 11 cats.

Background: Infestation of Lynxacarus radovskyi (Lynxacarosis) on cats is usually asymptomatic - most cats are presented with a dull, dry, dishevelled coat, with easily epilated hairs. The physical presence of the mite gives the coat a "peppered" appearance, and previous reports have described some cats developing pruritus and alopecia.

Objectives: To describe the clinical signs of Lynxacarus radovskyi associated self-induced alopecia.

Associations between increased body condition score, bodyweight, age and breed with urethral obstruction in male castrated cats.

Identifying potential risk factors for urethral obstruction in male cats may help in disease prevention. The aims of this study were to assess whether breed, pedigree status, age, bodyweight and body condition score (BCS) are risk factors for urethral obstruction in castrated male cats using a primary care population. Within this, a specific question was whether any increase in rate of urethral obstruction in male cats due to excess body condition is because of higher bodyweight.

Managing feline diabetes: current perspectives.

Diabetes mellitus is a common endocrine disease in cats. While type 2 diabetes is the most common form seen in cats, other underlying causes may contribute to insulin resistance. Guidelines for diagnosis vary and often do not take into account prediabetic cats.

Severe muscle fasciculations and tremor in a cat with hypochloraemic metabolic alkalosis secondary to duodenal obstruction.

Case Summary: An 18-month-old, female spayed, Australian Mist cat presented with a 24 h history of muscle tremors and inappetence progressing to collapse with generalised muscle fasciculations. The cat was diagnosed with a hypochloraemic metabolic alkalosis due to a duodenal foreign body found to be a trichobezoar at coeliotomy. The cat made a complete recovery after enterotomy to remove the trichobezoar, with cessation of neuromuscular clinical signs and normalisation of its electrolyte and acid-base imbalances.

Cerebral pyogranulomatous encephalitis caused by in a 15-week-old domestic shorthair kitten.

Case Summary: A case of cerebral phaeohyphomycosis caused by is described in a 15-week-old domestic shorthair kitten.

Relevance And Novel Information: Cerebral phaeohyphomycosis is a rare condition in cats caused by dematiaceous fungi. This report describes the clinical and histopathological findings in the youngest case documented in a feline, provides a brief review of aetiology, diagnosis, treatment and prognosis of cerebral phaeohyphomycosis and demonstrates the importance of molecular diagnostics in accurate mycotic species identification.

Diagnosis of prediabetes in cats: glucose concentration cut points for impaired fasting glucose and impaired glucose tolerance.

Diabetes is typically diagnosed in cats once clinical signs are evident. Diagnostic criteria for prediabetes in cats have not been defined. The objective of the study was to establish methodology and cut points for fasting and 2-h blood glucose concentrations in healthy client-owned senior cats (≥8 yr) using ear/paw samples and a portable glucose meter calibrated for feline blood.

Periodic hypokalaemic polymyopathy in Burmese and closely related cats: a review including the latest genetic data.

Global Importance: Hypokalaemic polymyopathy is a genetic disease of Burmese cats that has been encountered in Australasia, Europe and South Africa.

Clinical Features: Affected cats usually present with signs of muscle weakness and muscle pain in the first year of life. Although certain clinical features, such as ventroflexion of the head and neck, are especially characteristic, some cats do not display these signs.

Glycemic status and predictors of relapse for diabetic cats in remission.

Background: It is unknown if diabetic cats in remission have persistent abnormalities of glucose metabolism and should be considered prediabetic, or have normal glucose tolerance.

Objective: To characterize glycemic status of diabetic cats in remission and to determine predictors of relapse.

Animals: A total of 21 cats in diabetic remission and 28 healthy control cats.

Remission in cats: including predictors and risk factors.

This article summarizes current literature on diabetic remission in cats. Treatment options for diabetes mellitus are reviewed to highlight which protocols are most effective in achieving remission, as well as the importance of understanding the underlying pathophysiology that contributes to remission. In addition, current research into the glucose tolerance status of cats in diabetic remission and rates of relapse are discussed.

Retrospective case-control study of the effects of long-term dosing with meloxicam on renal function in aged cats with degenerative joint disease.

Medical records (2005-2009) of a feline-only practice were searched for cats with degenerative joint disease (DJD) treated using meloxicam. DJD was diagnosed by the presence of at least two of the following: (i) altered mobility (observed by the owner), (ii) abnormal physical findings, (iii) characteristic radiographic changes. The primary study cohort consisted of cats older than 7 years that had received meloxicam for variable intervals in excess of 6 months, and for which complete records were available.

Naturally occurring Tritrichomonas foetus infections in Australian cats: 38 cases.

A total of 38 cases of naturally occurring intestinal tritrichomoniasis in Australian cats are described. Detailed information was available for 13 cases diagnosed in two veterinary hospitals, one in Victoria and one in New South Wales (NSW). In all instances, presumptive microscopic diagnoses were confirmed by polymerase chain reaction (PCR) testing.

Fatal venous air embolism in a cat undergoing dental extractions.

A five-year-old domestic shorthair cat underwent general anaesthesia and tooth extractions. Immediately after use of a high-speed, air-driven, water-cooled dental drill, the cat suffered cardiac arrest and attempted resuscitation was unsuccessful. Post-mortem radiographs showed air in the vena cava, right atrium, right auricle and right ventricle, hepatic and renal veins.

Glargine and protamine zinc insulin have a longer duration of action and result in lower mean daily glucose concentrations than lente insulin in healthy cats.

The pharmacological effects of glargine, protamine zinc (PZI), and lente insulins were evaluated in nine healthy cats. A 3-way crossover study was performed and plasma concentrations of insulin and glucose were determined for 24 h after a single subcutaneous injection of each insulin at 3-day intervals. Time to onset of action did not differ between insulins.

Long-term safety, efficacy and palatability of oral meloxicam at 0.01-0.03 mg/kg for treatment of osteoarthritic pain in cats.

Osteoarthritis is a chronic, painful condition that is now recognised as affecting a large proportion of cats. Non-steroidal anti-inflammatory drugs (NSAIDs) have proven efficacy in dogs and humans but there are limited published data on the use of NSAIDs in the long-term management of this condition in cats. This prospective study aimed to assess the long-term safety and palatability of oral meloxicam and its efficacy in treating osteoarthritic pain in cats when given at a dose of 0.